Intention to Treat Analysis

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  Subject Areas on Research

  • A Fully Magnetically Levitated Circulatory Pump for Advanced Heart Failure. 
  • A Fully Magnetically Levitated Left Ventricular Assist Device - Final Report. 
  • A National Analysis of Short-term Outcomes and Long-term Survival Following Thoracoscopic Versus Open Lobectomy for Clinical Stage II Non-Small-Cell Lung Cancer. 
  • A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. 
  • A cluster-randomized controlled trial to assess the effectiveness of using 15% DEET topical repellent with long-lasting insecticidal nets (LLINs) compared to a placebo lotion on malaria transmission. 
  • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. 
  • A randomized trial of glutamine and antioxidants in critically ill patients. 
  • A randomized trial of urodynamic testing before stress-incontinence surgery. 
  • Adalimumab in Patients with Active Noninfectious Uveitis. 
  • Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer. 
  • Advanced heart failure patients supported with ambulatory inotropic therapy: What defines success of therapy? 
  • Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study. 
  • Analyzing phase III studies in hospice/palliative care. a solution that sits between intention-to-treat and per protocol analyses: the palliative-modified ITT analysis. 
  • Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. 
  • Anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence. 
  • Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. 
  • Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial. 
  • Association of obesity with cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: Insights from TECOS. 
  • Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. 
  • Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF. 
  • Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL). 
  • Clarifying selection bias in cluster randomized trials. 
  • Cognitive-behavioral therapy for PTSD and depression symptoms reduces risk for future intimate partner violence among interpersonal trauma survivors. 
  • Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial. 
  • Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma. 
  • Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement: Insights from the National Cardiovascular Data Registry Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. 
  • Continence pessary compared with behavioral therapy or combined therapy for stress incontinence: a randomized controlled trial. 
  • Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. 
  • Coronary-artery bypass surgery in patients with left ventricular dysfunction. 
  • Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury. 
  • Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis. 
  • Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis. 
  • Different Strokes for Different Folks. 
  • Diuretic strategies in patients with acute decompensated heart failure. 
  • Dose response to vitamin D supplementation in African Americans: results of a 4-arm, randomized, placebo-controlled trial. 
  • Duration of Adjuvant Chemotherapy for Stage III Colon Cancer. 
  • Early CPAP versus surfactant in extremely preterm infants. 
  • Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. 
  • Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial. 
  • Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial. 
  • Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial. 
  • Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. 
  • Effect of nesiritide in patients with acute decompensated heart failure. 
  • Effectiveness of switching from long-acting injectable fluphenazine or haloperidol decanoate to long-acting injectable risperidone microspheres: an open-label, randomized controlled trial. 
  • Effects of Extended-Release Niacin Added to Simvastatin/Ezetimibe on Glucose and Insulin Values in AIM-HIGH. 
  • Effects of red-cell storage duration on patients undergoing cardiac surgery. 
  • Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. 
  • Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF. 
  • Efficacy of the ketogenic diet in Lennox-Gastaut syndrome: a retrospective review of one institution's experience and summary of the literature. 
  • Enhancing standard cardiac rehabilitation with stress management training: background, methods, and design for the enhanced study. 
  • First-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial. 
  • Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement. 
  • Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. 
  • Global photographic assessment of men aged 18 to 60 years with male pattern hair loss receiving finasteride 1 mg or placebo. 
  • Group interventions for co-morbid insomnia and osteoarthritis pain in primary care: the lifestyles cluster randomized trial design. 
  • Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease. 
  • Ibrutinib in combination with rituximab in relapsed or refractory mantle cell lymphoma: a single-centre, open-label, phase 2 trial. 
  • Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia. 
  • Inference on treatment effects from a randomized clinical trial in the presence of premature treatment discontinuation: the SYNERGY trial. 
  • Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses of Clinical Trials. 
  • Intrapericardial Left Ventricular Assist Device for Advanced Heart Failure. 
  • Irrigation versus suction alone during laparoscopic appendectomy for perforated appendicitis: a prospective randomized trial. 
  • Laparoscopic anti-reflux surgery for the treatment of idiopathic pulmonary fibrosis (WRAP-IPF): a multicentre, randomised, controlled phase 2 trial. 
  • Laparoscopic versus open Ladd's procedure for intestinal malrotation in adults. 
  • Maintenance Sunitinib following Initial Platinum-Based Combination Chemotherapy in Advanced-Stage IIIB/IV Non-Small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Phase III Study-CALGB 30607 (Alliance). 
  • Major bleeding in patients with peripheral artery disease: Insights from the EUCLID trial. 
  • Male Circumcision Reduces Penile HPV Incidence and Persistence: A Randomized Controlled Trial in Kenya. 
  • Mobile health messages help sustain recent weight loss. 
  • Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma. 
  • New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference? 
  • Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial. 
  • Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC. 
  • Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial. 
  • Parent-reported homework problems in the MTA study: evidence for sustained improvement with behavioral treatment. 
  • Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. 
  • Percutaneous repair or surgery for mitral regurgitation. 
  • Phase II study of dose-attenuated bortezomib, cyclophosphamide and dexamethasone ("VCD-Lite") in very old or otherwise toxicity-vulnerable adults with newly diagnosed multiple myeloma. 
  • Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. 
  • Providing Rapid Out of Hospital Acute Cardiovascular Treatment 3 (PROACT-3). 
  • Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)-A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, recruitment, and baseline characteristics. 
  • Ranibizumab and bevacizumab for neovascular age-related macular degeneration. 
  • Rationale and design for a cluster randomized quality-improvement trial to increase the uptake of evidence-based therapies for patients at high cardiovascular risk: The BRIDGE-Cardiovascular Prevention trial. 
  • Recurrence of Atrial Fibrillation After Catheter Ablation or Antiarrhythmic Drug Therapy in the CABANA Trial. 
  • Reductions in alcohol and cocaine use following a group coping intervention for HIV-positive adults with childhood sexual abuse histories. 
  • Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital. 
  • Risk factors for conversion to cardiopulmonary bypass during off-pump coronary artery bypass surgery. 
  • Rituximab versus cyclophosphamide for ANCA-associated vasculitis. 
  • Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. 
  • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. 
  • Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure. 
  • Single-dose oritavancin in the treatment of acute bacterial skin infections. 
  • Surgery versus physical therapy for a meniscal tear and osteoarthritis. 
  • Survival with cardiac-resynchronization therapy in mild heart failure. 
  • Symptomatic event reduction with extended-duration betrixaban in acute medically ill hospitalized patients. 
  • Termination Based on Event Accrual in Per Protocol Versus Intention to Treat in the ROCKET AF Trial. 
  • The CSL112-2001 trial: Safety and tolerability of multiple doses of CSL112 (apolipoprotein A-I [human]), an intravenous formulation of plasma-derived apolipoprotein A-I, among subjects with moderate renal impairment after acute myocardial infarction. 
  • The Role of Neoadjuvant Chemotherapy in Patients With Resectable Malignant Pleural Mesothelioma-An Institutional and National Analysis. 
  • The effectiveness of the peer delivered Thinking Healthy Plus (THPP+) Programme for maternal depression and child socio-emotional development in Pakistan: study protocol for a three-year cluster randomized controlled trial. 
  • The efficacy of a daily self-weighing weight loss intervention using smart scales and e-mail. 
  • The implications of non-compliance: Randomised controlled trials: the intention-to-treat principle. 
  • The role of thoracoscopic pneumonectomy in the management of non-small cell lung cancer: A multicenter study. 
  • Three months of rifapentine and isoniazid for latent tuberculosis infection. 
  • Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial. 
  • Trastuzumab emtansine for HER2-positive advanced breast cancer. 
  • Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure. 
  • Ultrafiltration in Acute Heart Failure: Implications of Ejection Fraction and Early Response to Treatment From CARRESS-HF. 
  • Use and outcomes of antiarrhythmic therapy in patients with atrial fibrillation receiving oral anticoagulation: results from the ROCKET AF trial. 
  • Weight loss, exercise, or both and physical function in obese older adults. 
  • Within-Trial Evaluation of Medical Resources, Costs, and Quality of Life Among Patients With Type 2 Diabetes Participating in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL). 
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  Keywords of People

  • Allen, Nancy Bates, Professor Emeritus of Medicine, Medicine, Rheumatology and Immunology
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology