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Subject Areas on Research
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4th International Forum on Rheumatoid Arthritis: Great times near the Great Wall.
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A Roadmap for the Human Oral and Craniofacial Cell Atlas.
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A chemical method for labeling lysine methyltransferase substrates.
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A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.
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A multimodal cell census and atlas of the mammalian primary motor cortex.
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A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology.
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A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.
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Accelerated epigenetic aging in newborns with Down syndrome.
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Acetylation takes aim at mRNA.
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Advances in neuroscience.
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Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
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An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma.
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An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents.
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Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology.
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Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort.
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Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
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Bayesian genome- and epigenome-wide association studies with gene level dependence.
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Blood Epigenetic Age may Predict Cancer Incidence and Mortality.
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Body mass index associated with genome-wide methylation in breast tissue.
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Boosting, Not Breaking: CRISPR Activators Treat Disease Models.
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Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance.
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CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.
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CRISPR-based methods for high-throughput annotation of regulatory DNA.
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Can laboratory model systems instruct human limb regeneration?
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Can we identify meaningful epigenetic effects on human brain function and related risk for mental illness?
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Can we observe epigenetic effects on human brain function?
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Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
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Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins.
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Chromatin architecture reorganization during stem cell differentiation.
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Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.
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Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.
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Clinicopathological Features of Triple-Negative Breast Cancer Epigenetic Subtypes.
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Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.
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Common non-epigenetic drugs as epigenetic modulators.
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CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.
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Comparative cellular analysis of motor cortex in human, marmoset and mouse.
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Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.
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Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas.
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Comprehensive functional genomic resource and integrative model for the human brain.
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Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.
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DNA methylation atlas of the mouse brain at single-cell resolution.
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Defining the replication program through the chromatin landscape.
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Diastolic filling vortex forces and cardiac adaptations: probing the epigenetic nexus.
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Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes.
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Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
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Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression.
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Editing the Epigenome: Reshaping the Genomic Landscape.
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Editing the epigenome: technologies for programmable transcription and epigenetic modulation.
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Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance.
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Epigenetic determinants of ovarian clear cell carcinoma biology.
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Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii.
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Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.
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Epigenetics and autism spectrum disorder: A report of an autism case with mutation in H1 linker histone HIST1H1E and literature review.
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Epigenetics and psychostimulant addiction.
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Epigenetics in brain function.
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Epigenome characterization at single base-pair resolution.
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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.
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Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults.
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Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.
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Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
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Epigenome-wide association study of metabolic syndrome in African-American adults.
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Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma.
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Epigenomic diversity of cortical projection neurons in the mouse brain.
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Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture.
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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
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Epigenomics of centromere assembly and function.
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Evolutionary dynamics and information hierarchies in biological systems.
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Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression.
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Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.
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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
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Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
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Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.
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Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.
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Genomic and Epigenetic Foundations of Neocentromere Formation.
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Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
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Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
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Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci.
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Harnessing epigenetic variability for crop improvement: current status and future prospects.
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Highlights of the 2012 Research Workshop: Using nutrigenomics and metabolomics in clinical nutrition research.
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Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
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Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants.
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Identical twins carry a persistent epigenetic signature of early genome programming.
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Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data.
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Integrated epigenomics identifies BMP4 as a modulator of cisplatin sensitivity in gastric cancer.
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Integrative functional genomic analysis of human brain development and neuropsychiatric risks.
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Introduction to the Special Section on Epigenetics.
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Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models.
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Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.
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Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions.
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Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines.
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Main principles and outcomes of DNA methylation analysis.
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Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.
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Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study.
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Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation.
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Metabolic regulation of epigenetic remodeling in immune cells.
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Methylation subtypes and large-scale epigenetic alterations in gastric cancer.
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Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms.
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One-carbon metabolism and epigenetics: understanding the specificity.
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Opportunities-and hard work-ahead.
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Outcomes by Clinical and Molecular Features in Children With Medulloblastoma Treated With Risk-Adapted Therapy: Results of an International Phase III Trial (SJMB03).
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Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis.
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Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.
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Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions.
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Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.
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Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques.
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Strengthening Population Health Perspectives in Physical Therapist Practice Using Epigenetics.
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The BLUEPRINT Data Analysis Portal.
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The DNA methylation landscape of advanced prostate cancer.
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The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association.
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The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.
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The NIEHS TaRGET II Consortium and environmental epigenomics.
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The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis.
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The birth of the Epitranscriptome: deciphering the function of RNA modifications.
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The genetic regulatory signature of type 2 diabetes in human skeletal muscle.
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The impact of cellular metabolism on chromatin dynamics and epigenetics.
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The myth of genetic enhancement.
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Understanding risk for psychopathology through imaging gene-environment interactions.
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Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma.
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Bilbo, Staci D.,
Haley Family Professor of Psycology and Neuroscience,
Psychology & Neuroscience
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Liu, Yongmei,
Professor of Medicine,
Medicine, Cardiology
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Sullivan, Beth Ann,
Professor of Molecular Genetics and Microbiology,
Duke Science & Society
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Swain Lenz, Devi,
Research Scientist,
Biology
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Tung, Jenny,
Associate Professor of Evolutionary Anthropology,
Duke Science & Society
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Yan, Hai,
Adjunct Professor of Pathology,
Pathology