Transcription Factor 7-Like 1 Protein
-
Subject Areas on Research
- Analysis of the role of E2A-encoded proteins in insulin gene transcription.
- E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression.
- Functional replacement of the mouse E2A gene with a human HEB cDNA.
- Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB.
- Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis.
- Increase in PDX-1 levels suppresses insulin gene expression in RIN 1046-38 cells.
- Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.
- Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).
- The helix-loop-helix gene E2A is required for B cell formation.
- Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer.