Subject Areas on Research
- Delayed activation of spinal microglia contributes to the maintenance of bone cancer pain in female Wistar rats via P2X7 receptor and IL-18.
- Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
- Lack of the P2X7 receptor protects against AMD-like defects and microparticle accumulation in a chronic oxidative stress-induced mouse model of AMD.
- Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow.
- Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection.
- Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.
- Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis.
- Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.