Drug Repositioning
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Subject Areas on Research
- A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization.
- A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection.
- Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.
- Characteristics of Clinical Studies Used for US Food and Drug Administration Supplemental Indication Approvals of Drugs and Biologics, 2017 to 2019.
- Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials.
- Copper is required for oncogenic BRAF signalling and tumorigenesis.
- Exposure Matching of Pediatric Anti-infective Drugs: Review of Drugs Submitted to the Food and Drug Administration for Pediatric Approval.
- Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity.
- Identifying the macromolecular targets of de novo-designed chemical entities through self-organizing map consensus.
- KPT-330 Prevents Aortic Valve Calcification via a Novel C/EBPβ Signaling Pathway.
- Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors.
- New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate.
- Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential.
- Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection.
- Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma.
- Repurposing Medications for Hospice/Palliative Care Symptom Control Is No Longer Sufficient: A Manifesto for Change.
- Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission.
- Use Patents Can Be Useful: The Case of Rescued Drugs
- β-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19.