Drug Repositioning

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  Subject Areas on Research

  • A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization. 
  • A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection. 
  • Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19. 
  • Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials. 
  • Copper is required for oncogenic BRAF signalling and tumorigenesis. 
  • Exposure Matching of Pediatric Anti-infective Drugs: Review of Drugs Submitted to the Food and Drug Administration for Pediatric Approval. 
  • Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity. 
  • Identifying the macromolecular targets of de novo-designed chemical entities through self-organizing map consensus. 
  • New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate. 
  • Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection. 
  • Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma. 
  • Use Patents Can Be Useful: The Case of Rescued Drugs 
  • β-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19.