Neural Stem Cells
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Subject Areas on Research
- A comparative transcriptomic analysis of astrocytes differentiation from human neural progenitor cells.
- A detrimental role of RelB in mature oligodendrocytes during experimental acute encephalomyelitis.
- Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells.
- Adult c-Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons.
- An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus.
- An animal model of MYC-driven medulloblastoma.
- Analysis of neuronal proliferation, migration and differentiation in the postnatal brain using equine infectious anemia virus-based lentiviral vectors.
- Ank3-dependent SVZ niche assembly is required for the continued production of new neurons.
- Arl2- and Msps-dependent microtubule growth governs asymmetric division.
- Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells.
- Building bridges, not walls: spinal cord regeneration in zebrafish.
- CRL4Mahj E3 ubiquitin ligase promotes neural stem cell reactivation.
- Calorie restriction alleviates the age-related decrease in neural progenitor cell division in the aging brain.
- Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia.
- Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation.
- Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
- Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
- Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells.
- Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.
- Development and optimization of a dual-photoinitiator, emulsion-based technique for rapid generation of cell-laden hydrogel microspheres.
- Differentiation potential of individual olfactory c-Kit+ progenitors determined via multicolor lineage tracing.
- Diverse neurotoxicants target the differentiation of embryonic neural stem cells into neuronal and glial phenotypes.
- Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.
- Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury.
- Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation.
- Enhanced oncolytic virotherapy through oxidative stress inhibition.
- Enriching neural stem cell and anti-inflammatory glial phenotypes with electrical stimulation after traumatic brain injury in male rats.
- Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression.
- Fezf2 regulates telencephalic precursor differentiation from mouse embryonic stem cells.
- Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.
- Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.
- Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population.
- Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.
- Glucocorticoid hedgehog agonists in neurogenesis.
- High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.
- Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.
- Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex.
- Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture
- INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.
- Id proteins synchronize stemness and anchorage to the niche of neural stem cells.
- Imaging Biomaterial-Tissue Interactions.
- Immature excitatory neurons develop during adolescence in the human amygdala.
- In vitro models reveal differences in the developmental neurotoxicity of an environmental polycylic aromatic hydrocarbon mixture compared to benzo[a]pyrene: Neuronotypic PC12 Cells and embryonic neural stem cells.
- Injection of Microporous Annealing Particle (MAP) Hydrogels in the Stroke Cavity Reduces Gliosis and Inflammation and Promotes NPC Migration to the Lesion
- Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors.
- Intrinsically determined cell death of developing cortical interneurons.
- KDM1 class flavin-dependent protein lysine demethylases.
- LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.
- Lineage-specific laminar organization of cortical GABAergic interneurons.
- Live imaging of mitosis in the developing mouse embryonic cortex.
- Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
- MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex.
- Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.
- Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients.
- Moving messages in the developing brain-emerging roles for mRNA transport and local translation in neural stem cells.
- Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.
- Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma.
- Neural stem cell encapsulation and differentiation in strain promoted crosslinked polyethylene glycol-based hydrogels.
- Neural stem cell spacing questions their self-renewal.
- Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
- Next-generation Tumor-homing Induced Neural Stem Cells as an Adjuvant to Radiation for the Treatment of Metastatic Lung Cancer.
- PEDF & stem cells: niche vs. nurture.
- Peak density of immature nerve cells occurs with high-grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas.
- Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord.
- Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
- Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models.
- Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex.
- Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain.
- Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.
- Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming.
- Removal of microglial-specific MyD88 signaling alters dentate gyrus doublecortin and enhances opioid addiction-like behaviors.
- Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells.
- SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data.
- Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.
- Single-cell analysis of olfactory neurogenesis and differentiation in adult humans.
- Stoichiometric Post-Modification of Hydrogel Microparticles Dictates Neural Stem Cell Fate in Microporous Annealed Particle Scaffolds.
- Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain
- Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells.
- The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans.
- The spatial and temporal origin of chandelier cells in mouse neocortex.
- Transcription factor short stature homeobox 2 is required for proper development of tropomyosin-related kinase B-expressing mechanosensory neurons.
- Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
- Buckley, Anne Frances, Assistant Professor of Pathology, Pathology
- McLendon, Roger Edwin, Professor of Pathology, Pathology
- Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
- Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society
- Velkey, John Matthew, Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology