Molecular Sequence Annotation
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Subject Areas on Research
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A Chromosome-level Genome Assembly of the Highly Heterozygous Sea Urchin Echinometra sp. EZ Reveals Adaptation in the Regulatory Regions of Stress Response Genes.
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A cis-regulatory map of the Drosophila genome.
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A course-based research experience: how benefits change with increased investment in instructional time.
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A draft genome sequence of the elusive giant squid, Architeuthis dux.
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A high-resolution map of human evolutionary constraint using 29 mammals.
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Adaptive Radiation Genomics of Two Ecologically Divergent Hawai'ian Honeycreepers: The 'akiapōlā'au and the Hawai'i 'amakihi.
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An encyclopedia of mouse DNA elements (Mouse ENCODE).
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An integrated encyclopedia of DNA elements in the human genome.
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Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss.
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Architecture of the human regulatory network derived from ENCODE data.
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Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs.
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Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses.
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Comparative analysis of metazoan chromatin organization.
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Comparative genomics reveals insights into avian genome evolution and adaptation.
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Comparative genomics reveals molecular features unique to the songbird lineage.
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Comprehensive analysis of the chromatin landscape in Drosophila melanogaster.
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Connecting genetic risk to disease end points through the human blood plasma proteome.
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Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.
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Differential DNA methylation patterns in human Schlemm's canal endothelial cells with glaucoma.
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Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways.
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Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
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Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program.
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Draft genome of the fungicidal biological control agent Burkholderia anthina strain XXVI.
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Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
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Environmental adaptation contributes to gene polymorphism across the Arabidopsis thaliana genome.
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Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS.
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Functional Annotation Signatures of Disease Susceptibility Loci Improve SNP Association Analysis
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Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination.
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
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Gene Ontology annotations and resources.
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Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii.
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Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease.
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Global analysis of protein folding thermodynamics for disease state characterization.
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Identification of functional elements and regulatory circuits by Drosophila modENCODE.
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Improving the measurement of semantic similarity between gene ontology terms and gene products: insights from an edge- and IC-based hybrid method.
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Integrative annotation of variants from 1092 humans: application to cancer genomics.
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Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.
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Know Me! Unraveling the Riddle of Calcific Aortic Valve Disease by Bioinformatics.
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Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells.
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Loss of Drosophila melanogaster p21-activated kinase 3 suppresses defects in synapse structure and function caused by spastin mutations.
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MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.
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Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators.
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Mapping and characterization of structural variation in 17,795 human genomes.
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Methylomics of gene expression in human monocytes.
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Molecular and genetic evidence for a tetrapolar mating system in the basidiomycetous yeast Kwoniella mangrovensis and two novel sibling species.
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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
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POWRS: position-sensitive motif discovery.
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Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events.
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Patterns of gut bacterial colonization in three primate species.
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Perspectives from the Avian Phylogenomics Project: Questions that Can Be Answered with Sequencing All Genomes of a Vertebrate Class.
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Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases.
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Predicting gene structure changes resulting from genetic variants via exon definition features.
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Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis.
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Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl.
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RNA-seq: impact of RNA degradation on transcript quantification.
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Re-annotation of the woodland strawberry (Fragaria vesca) genome.
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SNiPA: an interactive, genetic variant-centered annotation browser.
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Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
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Six reference-quality genomes reveal evolution of bat adaptations.
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Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.
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Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits.
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The Disease and Gene Annotations (DGA): an annotation resource for human disease.
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The Gene Ontology: enhancements for 2011.
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The accessible chromatin landscape of the human genome.
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The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.
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Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs.
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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
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Using context to improve protein domain identification.
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VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era.
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Visual presentation as a welcome alternative to textual presentation of gene annotation information.
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dictyBase update 2011: web 2.0 functionality and the initial steps towards a genome portal for the Amoebozoa.
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Keywords of People