Chronic Pain

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  Subject Areas on Research

  • A Pilot Study of a Mobile Health Pain Coping Skills Training Protocol for Patients With Persistent Cancer Pain. 
  • A biopsychosocial-spiritual model of chronic pain in adults with sickle cell disease. 
  • A constant conversation: tuning into and harmonizing the needs and priorities of the body and mind. 
  • A pain research agenda for the 21st century. 
  • A phase I study of D-methadone in patients with chronic pain. 
  • A preliminary study comparing methadone and buprenorphine in patients with chronic pain and coexistent opioid addiction. 
  • A standard for terminology in chronic pelvic pain syndromes: A report from the chronic pelvic pain working group of the international continence society. 
  • A telephonic mindfulness-based intervention for persons with sickle cell disease: study protocol for a randomized controlled trial. 
  • A twisted tale: chronic abdominal pain caused by gastric volvulus. 
  • ACR Appropriateness Criteria® Chronic Chest Pain-Noncardiac Etiology Unlikely-Low to Intermediate Probability of Coronary Artery Disease. 
  • Acupuncture for Chronic Low Back Pain: Recommendations to Medicare/Medicaid from the Society for Acupuncture Research. 
  • Acupuncture for chronic pain: an update and critical overview. 
  • Acupuncture for the treatment or management of chronic pain. 
  • Age Group Comparisons of TENS Response Among Individuals With Chronic Axial Low Back Pain. 
  • Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival. 
  • Altered prefrontal correlates of monetary anticipation and outcome in chronic pain. 
  • An over-the-counter central sensitization therapy: a chronic back pain registry study of pain relief, medication use and their adverse effects. 
  • An overview of the management of post-vasectomy pain syndrome. 
  • Anger arousal and behavioral anger regulation in everyday life among patients with chronic low back pain: Relationships to patient pain and function. 
  • Anger arousal and behavioral anger regulation in everyday life among people with chronic low back pain: Relationships with spouse responses and negative affect. 
  • Application of a Value Model for the Prevention and Management of Chronic Musculoskeletal Pain by Physical Therapists. 
  • Applying a Lifespan Developmental Perspective to Chronic Pain: Pediatrics to Geriatrics. 
  • Assessment of physical function and participation in chronic pain clinical trials: IMMPACT/OMERACT recommendations. 
  • Association between physical activity and pain processing in adults with chronic low back pain compared to pain-free controls. 
  • Association of pain after trauma with long-term functional and mental health outcomes. 
  • Associations between cigarette smoking and pain among veterans. 
  • Benefits of the Restorative Exercise and Strength Training for Operational Resilience and Excellence Yoga Program for Chronic Low Back Pain in Service Members: A Pilot Randomized Controlled Trial. 
  • Biopsychosocial influence on shoulder pain: Rationale and protocol for a pre-clinical trial. 
  • Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study. 
  • CRHBP polymorphisms predict chronic pain development following motor vehicle collision. 
  • Can adding a standardized observational tool to interdisciplinary evaluation enhance the detection of pain in older adults with cognitive impairments? 
  • Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway. 
  • Care recipient agreeableness is associated with caregiver subjective physical health status. 
  • Catastrophizing and anxiety sensitivity mediate the relationship between persistent pain and emotional eating. 
  • Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study. 
  • Changes in regional gray matter volume in women with chronic pelvic pain: a voxel-based morphometry study. 
  • Characterization of Whole Body Pain in Urological Chronic Pelvic Pain Syndrome at Baseline: A MAPP Research Network Study. 
  • Chronic Musculoskeletal Pain is a Nervous System Disorder… Now What? 
  • Chronic abdominal pain in a liver transplant recipient. 
  • Chronic pain acceptance incrementally predicts disability in polytrauma-exposed veterans at baseline and 1-year follow-up. 
  • Chronic pain and analgesic use in CKD: implications for patient safety. 
  • Chronic pain and mental health: integrated solutions for global problems. 
  • Chronic widespread pain after motor vehicle collision typically occurs through immediate development and nonrecovery: results of an emergency department-based cohort study. 
  • Clinical findings and pain symptoms as potential risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study. 
  • Cognitive Mediators of Change in Physical Functioning in Response to a Multifaceted Intervention for Managing Osteoarthritis. 
  • Cognitive behavioral therapy for chronic pain is effective, but for whom? 
  • Cognitive-Behavioral-Based Physical Therapy for Patients With Chronic Pain Undergoing Lumbar Spine Surgery: A Randomized Controlled Trial. 
  • Cognitive-behavioral therapy increases prefrontal cortex gray matter in patients with chronic pain. 
  • Cold Water Pressor Test Differentially Modulates Functional Network Connectivity in Fibromyalgia Patients Compared with Healthy Controls. 
  • Comorbidities in patients with all-positive symptoms on sinonasal outcomes test quality-of-life instrument. 
  • Comorbidities in the first 2 years after arthroscopic hip surgery: substantial increases in mental health disorders, chronic pain, substance abuse and cardiometabolic conditions. 
  • Comparative Associations of Working Memory and Pain Catastrophizing With Chronic Low Back Pain Intensity. 
  • Comparative effectiveness of second-generation antidepressants for accompanying anxiety, insomnia, and pain in depressed patients: a systematic review. 
  • Complex multilocus effects of catechol-O-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision. 
  • Correlates of Health Care Seeking Activities in Patients with Urological Chronic Pelvic Pain Syndromes: Findings from the MAPP Cohort. 
  • Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. 
  • Deconstructing Chronic Low Back Pain in the Older Adult-Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part II: Myofascial Pain. 
  • Deconstructing Chronic Low Back Pain in the Older Adult-Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part X: Sacroiliac Joint Syndrome. 
  • Deconstructing chronic low back pain in the older adult--Step by step evidence and expert-based recommendations for evaluation and treatment part III: Fibromyalgia syndrome. 
  • Delivery strategies to optimize resource utilization and performance status for patients with advanced life-limiting illness: results from the "palliative care trial" [ISRCTN 81117481]. 
  • Development and validation of the French-Canadian Chronic Pain Self-efficacy Scale. 
  • Diagnosis and Treatment of Common Pain Syndromes and Disorders. 
  • Diagnostic accuracy of clinical tests of the hip: a systematic review with meta-analysis. 
  • Differential expression of systemic inflammatory mediators in amputees with chronic residual limb pain. 
  • Differential prescribing of opioid analgesics according to physician specialty for Medicaid patients with chronic noncancer pain diagnoses. 
  • Dorsal root ganglia pulsed radiofrequency treatment alters the spinal immune environment. 
  • Drivers and Risk Factors of Unplanned 30-Day Readmission Following Spinal Cord Stimulator Implantation. 
  • Effectiveness of an Internet-Delivered Exercise and Pain-Coping Skills Training Intervention for Persons With Chronic Knee Pain: A Randomized Trial. 
  • Effectiveness of spinal fusion versus structured rehabilitation in chronic low back pain patients with and without isthmic spondylolisthesis: a systematic review. 
  • Effects of a Home-Based Telephone-Supported Physical Activity Program for Older Adult Veterans With Chronic Low Back Pain. 
  • Emerging role of Toll-like receptors in the control of pain and itch. 
  • Emerging targets in neuroinflammation-driven chronic pain. 
  • Emotional reactions to pain predict psychological distress in adult patients with Sickle Cell Disease (SCD). 
  • Epigenetics and the transition from acute to chronic pain. 
  • Epigenetics of chronic pain after thoracic surgery. 
  • Epiregulin and EGFR interactions are involved in pain processing. 
  • Evaluation of an innovative spinal cord stimulator platform for the treatment of chronic pain. 
  • Evidence for brain glial activation in chronic pain patients. 
  • Evidence that Dry Eye Represents a Chronic Overlapping Pain Condition. 
  • Executive function in chronic pain patients and healthy controls: different cortical activation during response inhibition in fibromyalgia. 
  • Explantation Rates and Healthcare Resource Utilization in Spinal Cord Stimulation. 
  • Extensile decompression of the proximal and distal tarsal tunnel combined with partial plantar fascia release in the treatment of chronic plantar heel pain. 
  • Fatigue in Children With Sickle Cell Disease: Association With Neurocognitive and Social-Emotional Functioning and Quality of Life. 
  • Fertility challenges for women with sickle cell disease. 
  • Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. 
  • Glia and pain: is chronic pain a gliopathy? 
  • History of abuse and its relationship to pain experience and depression in women with chronic pelvic pain. 
  • Hybrid Statistical and Mechanistic Mathematical Model Guides Mobile Health Intervention for Chronic Pain. 
  • Identification of clusters of individuals relevant to temporomandibular disorders and other chronic pain conditions: the OPPERA study. 
  • Imaging Pain. 
  • Impact of Cigarette Smoking Status on Pain Intensity Among Veterans With and Without Hepatitis C. 
  • Impact of pregabalin on acute and persistent postoperative pain: a systematic review and meta-analysis. 
  • Improving care of chronic conditions for women veterans: identifying opportunities for comparative effectiveness research. 
  • In the eye of the beholder. 
  • Integrative Medicine Patients Have High Stress, Pain, and Psychological Symptoms. 
  • Interdisciplinary team-based care for patients with chronic pain on long-term opioid treatment in primary care (PPACT) - Protocol for a pragmatic cluster randomized trial. 
  • Intrathecal opioids for chronic pain: a call for evidence. 
  • Longer Delay From Chronic Pain to Spinal Cord Stimulation Results in Higher Healthcare Resource Utilization. 
  • Low back pain. 
  • Management of Chronic Pain in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline. 
  • Managing Chronic Pain in Cancer Survivors Prescribed Long-Term Opioid Therapy: A National Survey of Ambulatory Palliative Care Providers. 
  • Marijuana and Cannabinoids in ESRD and Earlier Stages of CKD. 
  • Mechanisms and models of spinal cord stimulation for the treatment of neuropathic pain. 
  • MicroRNA expression profiles differentiate chronic pain condition subtypes. 
  • Microglia and spinal cord synaptic plasticity in persistent pain. 
  • Microglial Signaling in Chronic Pain with a Special Focus on Caspase 6, p38 MAP Kinase, and Sex Dependence. 
  • Musculoskeletal Health: Addressing the Leading Causes of Disability. 
  • National Institutes of Health Pathways to Prevention Workshop: the role of opioids in the treatment of chronic pain. 
  • Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? 
  • Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. 
  • New modalities of neurostimulation: high frequency and dorsal root ganglion. 
  • No man is an island: living in a disadvantaged neighborhood influences chronic pain development after motor vehicle collision. 
  • Non-pharmacological treatment of chronic widespread musculoskeletal pain. 
  • Nonpharmacological Management of Pain: Convergence in Priorities Fuels the Drive for More Evidence. 
  • Nurse practitioners can effectively deliver pain coping skills training to osteoarthritis patients with chronic pain: A randomized, controlled trial. 
  • Occurrence, characteristics, and impact of chronic pain in formerly abused women. 
  • Oral Multimodal Analgesia for Total Joint Arthroplasty. 
  • Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification. 
  • Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice. 
  • PROMIS measures of pain, fatigue, negative affect, physical function, and social function demonstrated clinical validity across a range of chronic conditions. 
  • Pain Intensity and Pain Interference in Patients With Lung Cancer: A Pilot Study of Biopsychosocial Predictors. 
  • Pain Management: Road Map to Revolution. 
  • Pain acceptance, hope, and optimism: relationships to pain and adjustment in patients with chronic musculoskeletal pain. 
  • Pain and Urinary Symptoms Should Not be Combined into a Single Score: Psychometric Findings from the MAPP Research Network. 
  • Pain and emotion: a biopsychosocial review of recent research. 
  • Pain management strategies for thoracotomy and thoracic pain syndromes. 
  • Pain regulation by non-neuronal cells and inflammation. 
  • Pain-related fear and catastrophizing predict pain intensity and disability independently using an induced muscle injury model. 
  • Parent perceptions of child vulnerability are associated with functioning and health care use in children with chronic pain. 
  • Patient, Provider, and Combined Interventions for Managing Osteoarthritis in Primary Care: A Cluster Randomized Trial. 
  • Patient-Reported Outcomes and Fibromyalgia. 
  • Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. 
  • Perceived discrimination in health care is associated with a greater burden of pain in sickle cell disease. 
  • Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer. 
  • Persistent pain in chronically ill children without detectable disease activity. 
  • Physician Satisfaction in Treating Medically Unexplained Symptoms. 
  • Postoperative oxycodone toxicity in a patient with chronic pain and end-stage renal disease. 
  • Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. 
  • Potential neurobiological benefits of exercise in chronic pain and posttraumatic stress disorder: Pilot study. 
  • Potential psychosocial risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study. 
  • Predicting Low Back Pain Outcomes: Suggestions for Future Directions. 
  • Prediction of Persistent Musculoskeletal Pain at 12 Months: A Secondary Analysis of the Optimal Screening for Prediction of Referral and Outcome (OSPRO) Validation Cohort Study. 
  • Predictive relationships between chronic pain and negative emotions: a 4-month daily process study using Therapeutic Interactive Voice Response (TIVR). 
  • Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. 
  • Preliminary validation of the Michigan Body Map. 
  • Prevalence of Specific Types of Pain Diagnoses in a Sample of United States Adults. 
  • Prevention of chronic pain after surgical nerve injury: amputation and thoracotomy. 
  • Psychosocial interventions for managing pain in older adults: outcomes and clinical implications. 
  • Racial disparities across provider specialties in opioid prescriptions dispensed to medicaid beneficiaries with chronic noncancer pain. 
  • Recent progress in understanding the mechanisms of pain and itch. 
  • Relationship Between Chronic Conditions and Disability in African American Men and Women. 
  • Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects. 
  • Relieving pain in America: insights from an Institute of Medicine committee. 
  • Reporting of Sex Effects by Systematic Reviews on Interventions for Depression, Diabetes, and Chronic Pain. 
  • Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations. 
  • Resistance exercise, disability, and pain catastrophizing in obese adults with back pain. 
  • Resting-state functional connectivity predicts longitudinal pain symptom change in urologic chronic pelvic pain syndrome: a MAPP network study. 
  • Risk stratification of patients with low back pain seen in physical therapy practice. 
  • Self-system therapy for distress associated with persistent low back pain: A randomized clinical trial. 
  • Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: a MAPP Research Network study. 
  • Sickle Cell Disease: A Review of Nonpharmacological Approaches for Pain. 
  • Society of Behavioral Medicine (SBM) position statement: improving access to psychosocial care for individuals with persistent pain: supporting the National Pain Strategy's call for interdisciplinary pain care. 
  • Specialty-Based Variations in Spinal Cord Stimulation Success Rates for Treatment of Chronic Pain. 
  • Sphygmomanometry-evoked allodynia in chronic pain patients with and without fibromyalgia. 
  • Spouse criticism and hostility during marital interaction: effects on pain intensity and behaviors among individuals with chronic low back pain. 
  • Spouse-assisted training in pain coping skills and the outcome of multidisciplinary pain management for chronic low back pain treatment: a 1-year randomized controlled trial. 
  • Structural brain anomalies and chronic pain: a quantitative meta-analysis of gray matter volume. 
  • Summary of findings from the OPPERA baseline case-control study: implications and future directions. 
  • TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation. 
  • Taking ACTION to reduce pain: ACTION study rationale, design and protocol of a randomized trial of a proactive telephone-based coaching intervention for chronic musculoskeletal pain among African Americans. 
  • Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain. 
  • Temporal associations between spouse criticism/hostility and pain among patients with chronic pain: a within-couple daily diary study. 
  • The BraveNet prospective observational study on integrative medicine treatment approaches for pain. 
  • The Central Sensitization Inventory and Pain Sensitivity Questionnaire: An exploration of construct validity and associations with widespread pain sensitivity among individuals with shoulder pain. 
  • The Effects of Qigong for Adults with Chronic Pain: Systematic Review and Meta-Analysis. 
  • The Relationship between Pain, Disability, and Sex in African Americans. 
  • The Role of Cognitive Content and Cognitive Processes in Chronic Pain: An Important Distinction? 
  • The Volume-Outcome Effect: Impact on Trial-to-Permanent Conversion Rates in Spinal Cord Stimulation. 
  • The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee. 
  • The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis. 
  • The failed total ankle. 
  • The importance of psychological assessment in chronic pain. 
  • The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. 
  • The posterior medial cortex in urologic chronic pelvic pain syndrome: detachment from default mode network-a resting-state study from the MAPP Research Network. 
  • The promise and challenge of virtual gaming technologies for chronic pain: the case of graded exposure for low back pain. 
  • Transition to chronic pain: opportunities for novel therapeutics. 
  • Two colliding epidemics - obesity is independently associated with chronic pain interfering with activities of daily living in adults 18 years and over; a cross-sectional, population-based study. 
  • Unanticipated Insights into Biomedicine from the Study of Acupuncture. 
  • Understanding patterns and correlates of daily pain using the Sickle cell disease Mobile Application to Record Symptoms via Technology (SMART). 
  • Unlearning chronic pain: A randomized controlled trial to investigate changes in intrinsic brain connectivity following Cognitive Behavioral Therapy. 
  • Use of targeted transversus abdominus plane blocks in pediatric patients with anterior cutaneous nerve entrapment syndrome. 
  • Use of the SF-36v2 Health Survey as a Screen for Risk of Major Depressive Disorder in a US Population-based Sample and Subgroup With Chronic Pain. 
  • Variability in negative emotions among individuals with chronic low back pain: relationships with pain and function. 
  • Virtual reality for persistent pain: a new direction for behavioral pain management. 
  • What We Do (and Don't) Know About the Health Effects of Cannabis and Whether Marijuana Is Medicine. 
  • Widespread Psychosocial Difficulties in Men and Women With Urologic Chronic Pelvic Pain Syndromes: Case-control Findings From the Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network. 
  • Yoga may be noninferior to physical therapy for disability and pain at 12 weeks and both might improve function more than education in low resource adults with chronic nonspecific low back pain. 
  • β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain. 
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  Keywords of People

  • Martucci, Katherine, Assistant Professor in Anesthesiology, Anesthesiology