G1 Phase Cell Cycle Checkpoints

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  Subject Areas on Research

  • BET bromodomain inhibition of MYC-amplified medulloblastoma. 
  • Cell-cycle control of cell polarity in yeast. 
  • Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library. 
  • Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression. 
  • Mitogen-induced B-cell proliferation activates Chk2-dependent G1/S cell cycle arrest. 
  • NCKAP1 improves patient outcome and inhibits cell growth by enhancing Rb1/p53 activation in hepatocellular carcinoma. 
  • Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair. 
  • Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. 
  • Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.