Endoplasmic Reticulum Stress
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Subject Areas on Research
- A H(a)rd Way to Adapt in Cardiac Hypertrophy.
- Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA2β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes.
- Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability.
- Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
- Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae.
- Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells.
- Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration.
- DYT-TOR1A subcellular proteomics reveals selective vulnerability of the nuclear proteome to cell stress.
- Dangerous liaisons: flirtations between oncogenic BRAF and GRP78 in drug-resistant melanomas.
- Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival.
- Dietary ω-3 polyunsaturated fatty acids decrease retinal neovascularization by adipose-endoplasmic reticulum stress reduction to increase adiponectin.
- Distinct roles of specific fatty acids in cellular processes: implications for interpreting and reporting experiments.
- ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.
- ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
- Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress.
- Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.
- FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity.
- Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
- Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders.
- Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.
- Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity.
- High fat diet induces microbiota-dependent silencing of enteroendocrine cells.
- Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation.
- IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.
- IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity.
- Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells.
- Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity.
- KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance.
- MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa.
- Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis.
- PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis.
- Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes.
- Phosphorylation at tyrosine 262 promotes GADD34 protein turnover.
- Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes.
- Renal endoplasmic reticulum stress is coupled to impaired autophagy in a mouse model of GSD Ia.
- Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells.
- Salicylic acid-independent role of NPR1 is required for protection from proteotoxic stress in the plant endoplasmic reticulum.
- Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
- Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells.
- Targeting phosphorylation of eukaryotic initiation factor-2α to treat human disease.
- The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.
- The immunity-related GTPase Irgm3 relieves endoplasmic reticulum stress response during coxsackievirus B3 infection via a PI3K/Akt dependent pathway.
- The regulation of ferroptosis by MESH1 through the activation of the integrative stress response.
- The serine/threonine-protein kinase/endoribonuclease IRE1α protects the heart against pressure overload-induced heart failure.
- The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA.
- Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome.
- Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry.
- Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
- Unfolded protein response in brain ischemia: A timely update.