Genotyping Techniques

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  Subject Areas on Research

  • 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. 
  • A Common Polymorphism in SCN2A Predicts General Cognitive Ability through Effects on PFC Physiology. 
  • A Pragmatic, Randomized Controlled Trial of Oral Antivirals for the Treatment of Chronic Hepatitis C: The PRIORITIZE Study. 
  • A Review and Update on Papillary Immature Metaplasia of the Uterine Cervix: A Distinct Subset of Low-Grade Squamous Intraepithelial Lesion, Proposing a Possible Cell of Origin. 
  • A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. 
  • Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract. 
  • Association of CYP2C19 polymorphisms and lansoprazole-associated respiratory adverse effects in children. 
  • Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults. 
  • Cell-free DNA diagnostics in transplantation utilizing next generation sequencing. 
  • Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update. 
  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. 
  • Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. 
  • Combined genotype and haplotype tests for region-based association studies. 
  • Common Genetic Variation and Susceptibility to Ovarian Cancer: Current Insights and Future Directions. 
  • Comprehensive analysis of LAMC1 genetic variants in advanced pelvic organ prolapse. 
  • Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research. 
  • Cost-effectiveness analysis of genotyping for HLA-B*5801 and an enhanced safety program in gout patients starting allopurinol in Singapore. 
  • Detailed genetic characteristics of an international large cohort of patients with Stargardt disease: ProgStar study report 8. 
  • Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples. 
  • Endogenous Tagging at the cdh1 Locus for Live Visualization of E-Cadherin Dynamics. 
  • Ethnic variation in early age-related macular degeneration lesions between white Australians and Singaporean Asians. 
  • Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease. 
  • Factors influencing uptake of pharmacogenetic testing in a diverse patient population. 
  • Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. 
  • Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression. 
  • Genetic Dissection of Heritable Traits in Yeast Using Bulk Segregant Analysis. 
  • Genetic architecture of gene expression traits across diverse populations. 
  • Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. 
  • Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction. 
  • Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes. 
  • Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. 
  • Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia. 
  • Global and regional molecular epidemiology of HIV-1, 1990-2015: a systematic review, global survey, and trend analysis. 
  • Human disturbance causes the formation of a hybrid swarm between two naturally sympatric fish species. 
  • Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines. 
  • Leveraging Phylogenetics to Understand HIV Transmission and Partner Notification Networks. 
  • Matrix metalloproteinase-9 genetic polymorphisms and the risk for advanced pelvic organ prolapse. 
  • Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone. 
  • Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. 
  • Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy. 
  • Molecular Detection and Typing of Pathogenic Leptospira in Febrile Patients and Phylogenetic Comparison with Leptospira Detected among Animals in Tanzania. 
  • Multiplexed shotgun genotyping resolves species relationships within the North American genus Penstemon. 
  • Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. 
  • Overlap Extension Barcoding for the Next Generation Sequencing and Genotyping of Plasmodium falciparum in Individual Patients in Western Kenya. 
  • Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal. 
  • Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent. 
  • RNA-Seq optimization with eQTL gold standards. 
  • Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II. 
  • SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma. 
  • Significance of MDM2 and P14 ARF polymorphisms in susceptibility to differentiated thyroid carcinoma. 
  • Simultaneous Detection of Major Drug Resistance Mutations of HIV-1 Subtype B Viruses from Dried Blood Spot Specimens by Multiplex Allele-Specific Assay. 
  • Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. 
  • Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates. 
  • TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype. 
  • The genetic architecture of type 2 diabetes. 
  • The significance of single nucleotide polymorphism rs2070770 in CD20 gene in Chinese patients with diffuse large B-cell lymphoma. 
  • Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans. 
  • Using ERDS to infer copy-number variants in high-coverage genomes. 
  • Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility. 
  • Variants in PPP3R1 and MAPT are associated with more rapid functional decline in Alzheimer's disease: the Cache County Dementia Progression Study. 
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  Keywords of People

  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics