Asymmetric Cell Division

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  Subject Areas on Research

  • A bistable circuit involving SCARECROW-RETINOBLASTOMA integrates cues to inform asymmetric stem cell division. 
  • Asymmetric cell divisions in the epidermis. 
  • Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. 
  • Polar-opposite fates. 
  • Regulated spindle orientation buffers tissue growth in the epidermis. 
  • The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. 
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  Keywords of People

  • Lechler, Terry H., Professor in Dermatology, Cell Biology