Subject Areas on Research
- A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus.
- An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments.
- Beyond Hypothesis: Direct Evidence That V(D)J Recombination Is Regulated by the Accessibility of Chromatin Substrates.
- Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires.
- Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci.
- Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement.
- Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element.
- Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.
- Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow.
- Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development.
- Pillars Article: A Role for Histone Acetylation in the Developmental Regulation of V(D)J Recombination. Science. 2000. 287: 495-498.
- Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub.
- Tcrd Rearrangement Redirects a Processive Tcra Recombination Program to Expand the Tcra Repertoire.
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