Voltage-Gated Sodium Channels
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Subject Areas on Research
- A dual-target molecular mechanism of pyrethrum repellency against mosquitoes.
- Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids.
- Bioallethrin activates specific olfactory sensory neurons and elicits spatial repellency in Aedes aegypti.
- Calmodulin limits pathogenic Na+ channel persistent current.
- Characterization of two kdr mutations at predicted pyrethroid receptor site 2 in the sodium channels of Aedes aegypti and Nilaparvata lugens.
- Current view on regulation of voltage-gated sodium channels by calcium and auxiliary proteins.
- DSC1 channel-dependent developmental regulation of pyrethroid susceptibility in Drosophila melanogaster.
- Distinct functional properties of sodium channel variants are associated with usage of alternative exons in Nilaparvata lugens.
- Distinct modulating effects of TipE-homologs 2-4 on Drosophila sodium channel splice variants.
- Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel.
- Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy.
- Engineering prokaryotic channels for control of mammalian tissue excitability.
- Fibroblast Growth Factor Homologous Factors: New Roles in Neuronal Health and Disease.
- Fibroblast growth factor homologous factors in the heart: a potential locus for cardiac arrhythmias.
- Insight into the Mode of Action of Haedoxan A from Phryma leptostachya.
- Intron retention in mRNA encoding ancillary subunit of insect voltage-gated sodium channel modulates channel expression, gating regulation and drug sensitivity.
- Kilohertz waveforms optimized to produce closed-state Na+ channel inactivation eliminate onset response in nerve conduction block.
- Molecular Mechanism of Action and Selectivity of Sodium Ch annel Blocker Insecticides.
- Molecular basis of selective resistance of the bumblebee BiNav 1 sodium channel to tau-fluvalinate.
- Negative cross-resistance of a pyrethroid-resistant Drosophila mutant to Phryma leptostachya-derived haedoxan A.
- Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action.
- Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress.
- Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release.
- Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids.
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Keywords of People
- Jabba, Sairam V., Research Scientist, Anesthesiology
- Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology