RNA, Long Noncoding

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  Subject Areas on Research

  • A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking. 
  • A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers. 
  • A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. 
  • A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes. 
  • A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer. 
  • A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. 
  • A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus. 
  • A polymorphism in the HCP5 gene associated with HLA-B*5701 does not restrict HIV-1 in vitro. 
  • A whole-genome association study of major determinants for host control of HIV-1. 
  • Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs. 
  • An FGF-WNT gene regulatory network controls lung mesenchyme development. 
  • Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies. 
  • Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. 
  • Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin. 
  • CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States. 
  • Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. 
  • Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. 
  • Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries. 
  • Dawn of the Epi-LncRNAs: new path from Myheart. 
  • Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. 
  • Deep-RACE: Comprehensive Search for Novel ncRNAs Associated to a Specific Locus. 
  • Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. 
  • Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas. 
  • Discovery of Small Molecule Ligands for MALAT1 by Tuning an RNA-Binding Scaffold. 
  • EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs. 
  • Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients. 
  • Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture. 
  • Essential Role of Non-Coding RNAs in Enterovirus Infection: From Basic Mechanisms to Clinical Prospects. 
  • Exclusion of maternal uniparental disomy of chromosome 14 in patients referred for Prader-Willi syndrome using a multiplex methylation polymerase chain reaction assay. 
  • Expression and prognostic impact of lncRNAs in acute myeloid leukemia. 
  • Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer. 
  • Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. 
  • Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch. 
  • Extracellular vesicles from endometriosis patients are characterized by a unique miRNA-lncRNA signature. 
  • Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer. 
  • From the RNA world to the clinic. 
  • Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. 
  • Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. 
  • High-Resolution Expression Map of the Arabidopsis Root Reveals Alternative Splicing and lincRNA Regulation. 
  • Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1. 
  • Identification of Long Noncoding RNAs Associated to Human Disease Susceptibility. 
  • Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. 
  • JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. 
  • LINC00675 activates androgen receptor axis signaling pathway to promote castration-resistant prostate cancer progression. 
  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions. 
  • LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling. 
  • LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin. 
  • LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling. 
  • LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. 
  • LncRNA-MAP3K4 regulates vascular inflammation through the p38 MAPK signaling pathway and cis-modulation of MAP3K4. 
  • LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition. 
  • Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. 
  • Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function. 
  • Long Noncoding RNAs in Atherosclerosis and Vascular Injury: Pathobiology, Biomarkers, and Targets for Therapy. 
  • Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancer. 
  • Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer. 
  • Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers. 
  • Longevity-related molecular pathways are subject to midlife "switch" in humans. 
  • Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains. 
  • Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro . 
  • N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding. 
  • N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein. 
  • Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example. 
  • Noncoding RNAs Regulating Cancer Signaling Network. 
  • Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association. 
  • Noncoding RNAs: biology and applications-a Keystone Symposia report. 
  • Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation. 
  • Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study. 
  • Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. 
  • PCGEM1, a prostate-specific gene, is overexpressed in prostate cancer. 
  • Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. 
  • Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. 
  • Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort. 
  • Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans. 
  • SFPQ promotes an oncogenic transcriptomic state in melanoma. 
  • SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells. 
  • Sensitive and quantitative probing of pseudouridine modification in mRNA and long noncoding RNA. 
  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes. 
  • Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. 
  • The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. 
  • The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors. 
  • The Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways. 
  • The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans. 
  • The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. 
  • The molecular mechanism of LncRNA34a-mediated regulation of bone metastasis in hepatocellular carcinoma. 
  • Transcriptomics Profiling of Alzheimer's Disease Reveal Neurovascular Defects, Altered Amyloid-β Homeostasis, and Deregulated Expression of Long Noncoding RNAs. 
  • Unwinding the Role of FACT in Cas9-based Genome Editing. 
  • Viruses hijack a long non-coding RNA. 
  • Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut. 
  • Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation. 
  • Xist RNA is a potent suppressor of hematologic cancer in mice. 
  • Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis. 
  • lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. 
  • lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma. 
  • mir-17-92: a polycistronic oncomir with pleiotropic functions.