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Claudin-1
Subject Areas on Research
Correlation of the tight junction-like distribution of Claudin-1 to the cellular tropism of hepatitis C virus.
Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection.
Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.
