Mitochondrial Dynamics
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Subject Areas on Research
- Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation.
- BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.
- Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability.
- Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.
- Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors.
- Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.
- Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage.
- MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria.
- Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans
- Mitochondrial fusion, fission, and mitochondrial toxicity.
- Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission.
- S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy.
- Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle.