Rho Guanine Nucleotide Exchange Factors
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Subject Areas on Research
- A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion.
- A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.
- Calcium-sensing receptor activation of rho involves filamin and rho-guanine nucleotide exchange factor.
- Early de novo DNA methylation and prolonged demethylation in the muscle lineage.
- Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.
- Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis.
- Muscle giants: molecular scaffolds in sarcomerogenesis.
- Regulator of G-protein signaling (RGS) proteins in cancer biology.
- Selective activation of human atrial Galpha12 and Galpha13 by Galphaq-coupled angiotensin and endothelin receptors.
- Selective uncoupling of G alpha 12 from Rho-mediated signaling.
- TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.
- The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.
- Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.