Matrilin Proteins
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Subject Areas on Research
- A complete algorithm to resolve ambiguity for intersubunit NOE assignment in structure determination of symmetric homo-oligomers.
- A mutation in cartilage oligomeric matrix protein (COMP) causes early-onset osteoarthritis in a large kindred study.
- Altered synthesis of cartilage-specific proteoglycans by mutant human cartilage oligomeric matrix protein.
- Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model.
- Assessment of the utility of biomarkers of osteoarthritis in the guinea pig.
- Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study.
- Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study.
- Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?
- Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al.
- Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis.
- Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein: the Johnston County Osteoarthritis Project.
- Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family.
- Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
- Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels.
- Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA.
- Nanostring-based multigene assay to predict recurrence for gastric cancer patients after surgery.
- Protein modification by deamidation indicates variations in joint extracellular matrix turnover.
- Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis.
- Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology.
- Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: the Johnston County Osteoarthritis Project.
- Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis.
- Serum levels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteoarthritis.
- The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants.
- Urea as a passive transport marker for arthritis biomarker studies.
- Variation in osteoarthritis biomarkers from activity not food consumption.
- Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation.