Cartilage Oligomeric Matrix Protein
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Subject Areas on Research
- A mutation in cartilage oligomeric matrix protein (COMP) causes early-onset osteoarthritis in a large kindred study.
- Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs.
- Assessment of the utility of biomarkers of osteoarthritis in the guinea pig.
- Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study.
- Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study.
- Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?
- Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing.
- Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons.
- Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al.
- Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis.
- Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein: the Johnston County Osteoarthritis Project.
- Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family.
- In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity.
- Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels.
- Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA.
- Protein modification by deamidation indicates variations in joint extracellular matrix turnover.
- Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis.
- Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology.
- Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: the Johnston County Osteoarthritis Project.
- Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis.
- Serum levels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteoarthritis.
- Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.
- Urea as a passive transport marker for arthritis biomarker studies.
- Variation in osteoarthritis biomarkers from activity not food consumption.
- Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation.