Mad2 Proteins

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  Subject Areas on Research

  • A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. 
  • Distinct responses to reduplicated chromosomes require distinct Mad2 responses. 
  • Multifaceted recognition of vertebrate Rev1 by translesion polymerases ζ and κ. 
  • Nomenclature: vertebrate mediators of TGFbeta family signals. 
  • Ploidy variation in multinucleate cells changes under stress. 
  • REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. 
  • Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer.