MEF2 Transcription Factors
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Subject Areas on Research
- A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
- Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway.
- Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.
- Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation.
- Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro.
- Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene.
- Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
- Genetic loci for retinal arteriolar microcirculation.
- Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans.
- Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient.
- Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
- Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.
- Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca.
- MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type.
- Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization.
- Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers.
- Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.
- Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications.
- Stoichiometry of Gata4, Mef2c, and Tbx5 influences the efficiency and quality of induced cardiac myocyte reprogramming.
- Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter.
- The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4.
- The NMDA receptor subunit GluN3A regulates synaptic activity-induced and myocyte enhancer factor 2C (MEF2C)-dependent transcription.
- The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.
- The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity.
- The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2.
- Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming.