Death-Associated Protein Kinases

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  Subject Areas on Research

  • Aberrant promoter methylation of multiple genes in non-small cell lung cancers. 
  • De Novo Fragment Design for Drug Discovery and Chemical Biology. 
  • Death-associated protein kinase 1 promotes growth of p53-mutant cancers. 
  • Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase. 
  • Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor. 
  • Identification of the endogenous smooth muscle myosin phosphatase-associated kinase. 
  • Par-4 downregulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy. 
  • Phosphorylation-dependent control of ZIPK nuclear import is species specific. 
  • ROCK1 phosphorylates and activates zipper-interacting protein kinase. 
  • Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes. 
  • Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition. 
  • Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides. 
  • Targeting Pim Kinases and DAPK3 to Control Hypertension. 
  • ZIP kinase, a key regulator of myosin protein phosphatase 1.