Allografts

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  Subject Areas on Research

  • 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection. 
  • A 2020 Banff Antibody-mediatedInjury Working Group examination of international practices for diagnosing antibody-mediated rejection in kidney transplantation - a cohort study. 
  • A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy. 
  • APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors. 
  • Acute cellular and antibody-mediated allograft rejection. 
  • Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality. 
  • Amiodarone use in patients listed for heart transplant is associated with increased 1-year post-transplant mortality. 
  • Amphiregulin contributes to airway remodeling in chronic allograft dysfunction after lung transplantation. 
  • An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD. 
  • Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation. 
  • Anti-Angiotensin II Type 1 Receptor and Anti-Endothelial Cell Antibodies: A Cross-Sectional Analysis of Pathological Findings in Allograft Biopsies. 
  • Anti-TCR mAb induces peripheral tolerance to alloantigens and delays islet allograft rejection in autoimmune diabetic NOD mice. 
  • Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation. 
  • Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure. 
  • Assessment of cardiac allograft systolic function by global longitudinal strain: From donor to recipient. 
  • Autologous/Allogeneic Hematopoietic Cell Transplantation versus Tandem Autologous Transplantation for Multiple Myeloma: Comparison of Long-Term Postrelapse Survival. 
  • B-cell activating factor (BAFF) plasma level at the time of chronic GvHD diagnosis is a potential predictor of non-relapse mortality. 
  • Banff Lung Report: Current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody-mediated rejection (AMR). 
  • Banff study of pathologic changes in lung allograft biopsy specimens with donor-specific antibodies. 
  • Bone Graft Options in Upper-Extremity Surgery. 
  • Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression. 
  • CCL-21 conditioned regulatory T cells induce allotolerance through enhanced homing to lymphoid tissue. 
  • CD57(+) CD4 T Cells Underlie Belatacept-Resistant Allograft Rejection. 
  • Cardiac Allograft Vasculopathy: A Formidable Foe. 
  • Cardiac allograft vasculopathy after heart transplantation: current prevention and treatment strategies. 
  • Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury. 
  • Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome-A consensus report from the Pulmonary Council of the ISHLT. 
  • Circulating mitochondria in organ donors promote allograft rejection. 
  • Clinical predictors and outcome implications of early readmission in lung transplant recipients. 
  • Clofarabine Plus Busulfan is an Effective Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Lymphoblastic Leukemia: Long-Term Study Results. 
  • Cognitive problems following hematopoietic stem cell transplant: relationships with sleep, depression and fatigue. 
  • Commentary: The burning questions of reflux management in lung transplantation. 
  • Comparison of 3D Printed Spherical Implants versus Femoral Head Allografts for Tibiotalocalcaneal Arthrodesis. 
  • Consensus diagnostic histopathological criteria for acute gastrointestinal graft versus host disease improve interobserver reproducibility. 
  • Cromolyn ameliorates acute and chronic injury in a rat lung transplant model. 
  • Cultured thymus tissue implantation promotes donor-specific tolerance to allogeneic heart transplants. 
  • DAMP-Induced Allograft and Tumor Rejection: The Circle Is Closing. 
  • Damage-Associated Molecular Patterns Induce Inflammatory Injury During Machine Preservation of the Liver: Potential Targets to Enhance a Promising Technology. 
  • Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation. 
  • Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes. 
  • Depressive Symptoms, Exercise Capacity, and Clinical Outcomes After Lung Transplantation. 
  • Dissecting the human kidney allograft transcriptome: single-cell RNA sequencing. 
  • Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation? Clinical article. 
  • Donor apoptotic cell-based therapy for effective inhibition of donor-specific memory T and B cells to promote long-term allograft survival in allosensitized recipients. 
  • Donor derived HSV hepatitis in a kidney transplant recipient leading to liver fibrosis and portal hypertension. 
  • Donor liver apoptosis is associated with early allograft dysfunction and decreased short-term graft survival after liver transplantation. 
  • Dual Procurement of Lung and Heart Allografts Does Not Negatively Affect Lung Transplant Outcomes. 
  • Effect of HMG CoA reductase inhibitors on the development of chronic lung allograft dysfunction. 
  • Effect of cord blood processing on transplantation outcomes after single myeloablative umbilical cord blood transplantation. 
  • Effect of cyclic strain on tensile properties of a naturally derived, decellularized tendon scaffold seeded with allogeneic tenocytes and associated messenger RNA expression. 
  • Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the Multicenter ACL Revision Study (MARS) Cohort. 
  • Effectiveness of Allograft Reconstruction vs Tenodesis for Irreparable Peroneus Brevis Tears: A Cadaveric Model. 
  • Effects of Ideal Versus Total Body Weight Dosage of Rabbit Antithymocyte Globulin on Outcomes of Kidney Transplant Patients With High Immunologic Risk. 
  • Efficacy of Particulated Juvenile Cartilage Allograft Transplantation for Osteochondral Lesions of the Talus. 
  • Efficacy of a Cellular Allogeneic Bone Graft in Foot and Ankle Arthrodesis Procedures. 
  • Efficacy of a Cellular Bone Allograft for Foot and Ankle Arthrodesis and Revision Nonunion Procedures. 
  • Equalizing MELD Scores Over Broad Geographies Is Not the Most Efficacious Way to Allocate a Scarce Resource in a Value-based Environment. 
  • Evidence of Chronic Allograft Injury in Liver Biopsies From Long-term Pediatric Recipients of Liver Transplants. 
  • Ex Situ Limb Perfusion System to Extend Vascularized Composite Tissue Allograft Survival in Swine. 
  • Factors Associated with Long-Term Risk of Relapse after Unrelated Cord Blood Transplantation in Children with Acute Lymphoblastic Leukemia in Remission. 
  • Factors Influencing Graft Choice in Revision Anterior Cruciate Ligament Reconstruction in the MARS Group. 
  • Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy. 
  • Fivefold higher rate of pseudarthrosis with polyetheretherketone interbody device than with structural allograft used for 1-level anterior cervical discectomy and fusion. 
  • Fresh Osteochondral Allograft Transplantation for Osteochondral Lesions of the Talus: A Systematic Review. 
  • Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft. 
  • Gut Colonization Preceding Mucosal Barrier Injury Bloodstream Infection in Pediatric Hematopoietic Stem Cell Transplantation Recipients. 
  • HLA-Mismatched Microtransplant in Older Patients Newly Diagnosed With Acute Myeloid Leukemia: Results From the Microtransplantation Interest Group. 
  • Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Children and Adolescents with Fanconi Anemia. 
  • Hematopoietic Stem Cell Transplantation for CD40 Ligand Deficiency: Single Institution Experience. 
  • Hematopoietic Stem Cell Transplantation to Treat Leukodystrophies: Clinical Practice Guidelines from the Hunter's Hope Leukodystrophy Care Network. 
  • Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction. 
  • Host-Pathogen Interactions and Chronic Lung Allograft Dysfunction. 
  • How I treat sinusoidal obstruction syndrome. 
  • Hyaluronan contributes to bronchiolitis obliterans syndrome and stimulates lung allograft rejection through activation of innate immunity. 
  • Impact of EGF, IL28B, and PNPLA3 polymorphisms on the outcome of allograft hepatitis C: a multicenter study. 
  • Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft. 
  • Impact of donor and recipient age difference on long-term allograft survival after living donor renal transplantation: analysis of 478 cases. 
  • Impact of post-ASCT maintenance therapy on outcomes in patients with newly diagnosed multiple myeloma in Connect MM. 
  • Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection. 
  • Important impact of gingival and periodontal conditions on outcomes in SCT recipients. 
  • Improved Detection of Cardiac Allograft Vasculopathy: A Multi-Institutional Analysis of Functional Parameters in Pediatric Heart Transplant Recipients. 
  • In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA/PTX3 complex purified from amniotic membrane. 
  • Incidence, significance, and persistence of human coronavirus infection in hematopoietic stem cell transplant recipients. 
  • Induction of cardiac allograft tolerance across a full MHC barrier in miniature swine by donor kidney cotransplantation. 
  • Infections after upper extremity allotransplantation: a worldwide population cohort study, 1998-2017. 
  • Inhibition of αvβ6 promotes acute renal allograft rejection in nonhuman primates. 
  • Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion. 
  • Kidney allograft survival of African American and Caucasian American recipients with lupus. 
  • Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. 
  • Large fresh osteochondral allografts of the knee: a systematic clinical and basic science review of the literature. 
  • Late Gastrointestinal Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Adults. 
  • Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation. 
  • Lithiasis of the renal allograft, a rare urological complication following renal transplantation: a single-center experience of 2,045 renal transplantations. 
  • Long-Term Follow-up of CALGB (Alliance) 100001: Autologous Followed by Nonmyeloablative Allogeneic Transplant for Multiple Myeloma. 
  • Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes. 
  • Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. 
  • Management of Complications of Achilles Tendon Surgery. 
  • Memory T cells: A helpful guard for allogeneic hematopoietic stem cell transplantation without causing graft-versus-host disease. 
  • Meniscal allograft transplantation. Part 1: systematic review of graft biology, graft shrinkage, graft extrusion, graft sizing, and graft fixation. 
  • Meniscal allograft transplantation. Part 2: systematic review of transplant timing, outcomes, return to competition, associated procedures, and prevention of osteoarthritis. 
  • Meniscal allograft transplantation: a systematic review. 
  • MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. 
  • Microtransplantation in older patients with AML: A pilot study of safety, efficacy and immunologic effects. 
  • Minimally Invasive Corneal Neurotization With Acellular Nerve Allograft: Surgical Technique and Clinical Outcomes. 
  • Monitoring the kinetics of B-cell recovery following rituximab may guide the management of steroid-refractory chronic GvHD. 
  • Osteocel Plus cellular allograft in anterior cervical discectomy and fusion: evaluation of clinical and radiographic outcomes from a prospective multicenter study. 
  • Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome. 
  • Outcomes after percutaneous coronary artery revascularization procedures for cardiac allograft vasculopathy in pediatric heart transplant recipients: A multi-institutional study. 
  • Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors. 
  • Outcomes of Bone Grafting of Bone Cysts After Total Ankle Arthroplasty. 
  • Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression. 
  • PD-1-dependent restoration of self-tolerance in the NOD mouse model of diabetes after transient anti-TCRβ mAb therapy. 
  • Particulated juvenile articular cartilage allograft transplantation for osteochondral lesions of the knee and ankle. 
  • Patient demographics and surgical characteristics in ACL revision: a comparison of French, Norwegian, and North American cohorts. 
  • Patient perspectives on physical function after allogeneic hematopoietic stem cell transplantation: a qualitative study. 
  • Phase II Trial of Graft-versus-Host Disease Prophylaxis with Post-Transplantation Cyclophosphamide after Reduced-Intensity Busulfan/Fludarabine Conditioning for Hematological Malignancies. 
  • Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. 
  • Podocyte density is reduced in kidney allografts with high-risk APOL1 genotypes at transplantation. 
  • Predictors of De Novo Nonalcoholic Fatty Liver Disease After Liver Transplantation and Associated Fibrosis. 
  • Preemptive donor apoptotic cell infusions induce IFN-γ-producing myeloid-derived suppressor cells for cardiac allograft protection. 
  • Prognostic significance of early pulmonary function changes after onset of chronic lung allograft dysfunction. 
  • Prospective Evaluation of Structural Allograft Transplantation for Osteochondral Lesions of the Talar Shoulder. 
  • Pure Red Cell Aplasia in Major ABO-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Is Associated with Severe Pancytopenia. 
  • Putting the 2019 CLAD consensus definitions to the test: Two steps forward, one step back? 
  • Quantifying renal allograft loss following early antibody-mediated rejection. 
  • Recipient Myd88 Deficiency Promotes Spontaneous Resolution of Kidney Allograft Rejection. 
  • Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. 
  • Rejection in the setting of non-HLA antibody: New tools for navigating bench to bedside. 
  • Role of Fresh Osteochondral Allografts for Large Talar Osteochondral Lesions. 
  • Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood. 
  • Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation. 
  • Studies Introducing Costimulation Blockade for Vascularized Composite Allografts in Nonhuman Primates. 
  • Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission. 
  • The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease. 
  • The Effect of Ex Situ Perfusion in a Swine Limb Vascularized Composite Tissue Allograft on Survival up to 24 Hours. 
  • The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice. 
  • The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). 
  • The high failure rate of biologic resurfacing of the glenoid in young patients with glenohumeral arthritis. 
  • The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD. 
  • The role of MR imaging in the assessment of renal allograft vasculature. 
  • Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity. 
  • Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice. 
  • Treatment Journeys of Patients With Newly Diagnosed Multiple Myeloma (NDMM): Results From The Connect MM Registry. 
  • Urine Metabolite Profiles Predictive of Human Kidney Allograft Status. 
  • Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection. 
  • Validation and Refinement of Chronic Lung Allograft Dysfunction Phenotypes in Bilateral and Single Lung Recipients. 
  • Vascularized composite allotransplants as a mechanistic model for allograft rejection - an experimental study. 
  • Why Do Osteochondral Allografts Survive? Comparative Analysis of Cartilage Biochemical Properties Unveils a Molecular Basis for Durability.