Cell- and Tissue-Based Therapy
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Subject Areas on Research
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A cord blood monocyte-derived cell therapy product accelerates brain remyelination.
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A tutorial on the use of exploratory efficacy outcomes in uncontrolled phase I cell therapy trials.
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An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs.
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Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells.
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Apoptotic Donor Cells in Transplantation.
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Apoptotic cell-based therapies for promoting transplantation tolerance.
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Applications of Gene Editing Technologies to Cellular Therapies.
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Autologous CD34+ Cell Therapy for Refractory Angina: 2-Year Outcomes From the ACT34-CMI Study.
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Autologous Cord Blood Infusions Are Safe and Feasible in Young Children with Autism Spectrum Disorder: Results of a Single-Center Phase I Open-Label Trial.
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Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial.
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Avascular necrosis in pediatric systemic lupus erythematosus: a brief report and review of the literature.
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Basic and Translational Research in Cardiac Repair and Regeneration: JACC State-of-the-Art Review.
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Biobehavioral Research and Hematopoietic Stem Cell Transplantation: Expert Review from the Biobehavioral Research Special Interest Group of the American Society for Transplantation and Cellular Therapy.
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Cardiac regeneration.
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Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors.
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Cell therapy for heart failure: the need for a new therapeutic strategy.
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Cell therapy for lung diseases. Report from an NIH-NHLBI workshop, November 13-14, 2012.
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Cell-based gene therapy for repair of critical size defects in the rat fibula.
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Cell-based interventions for neurologic conditions: ethical challenges for early human trials.
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Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome.
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Cellular Therapies in Solid Organ Allotransplantation: Promise and Pitfalls.
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Chemically induced proximity in biology and medicine.
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Chimeric antigen receptor (CAR) T-cell therapy for multiple myeloma.
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Comparison of Cilta-cel, an Anti-BCMA CAR-T Cell Therapy, Versus Conventional Treatment in Patients With Relapsed/Refractory Multiple Myeloma.
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Current perspectives on the use of ancillary materials for the manufacture of cellular therapies.
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DTI Tract-Based Quantitative Susceptibility Mapping: An Initial Feasibility Study to Investigate the Potential Role of Myelination in Brain Connectivity Change in Cerebral Palsy Patients During Autologous Cord Blood Cell Therapy Using a Rotationally-Invariant Quantitative Measure.
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Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy.
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Distinct Responses of Stem Cells to Telomere Uncapping-A Potential Strategy to Improve the Safety of Cell Therapy.
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Do We Need Full Donor Chimerism? How Alloreactive Cell Therapies without Substantial Engraftment Might Treat Hematologic Cancers.
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Does transendocardial injection of mesenchymal stem cells improve myocardial function locally or globally?: An analysis from the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) randomized trial.
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Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.
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Efficacy and Safety of MSC Cell Therapies for Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis.
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Efficient intratracheal delivery of airway epithelial cells in mice and pigs.
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Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies.
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Epidermal growth factor receptor and variant III targeted immunotherapy.
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Genome engineering: a new approach to gene therapy for neuromuscular disorders.
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Genome-editing Technologies for Gene and Cell Therapy.
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Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models.
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Immunotherapy for Glioblastoma: Adoptive T-cell Strategies.
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Injectable biomaterial shuttles for cell therapy in stroke.
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Interneurons from embryonic development to cell-based therapy.
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IxCELL-DCM: rejuvenation for cardiac regenerative therapy?
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Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices.
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Migration of human dendritic cells after injection in patients with metastatic malignancies.
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Motor function and safety after allogeneic cord blood and cord tissue-derived mesenchymal stromal cells in cerebral palsy: An open-label, randomized trial.
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Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.
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Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial.
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Preclinical characterization of DUOC-01, a cell therapy product derived from banked umbilical cord blood for use as an adjuvant to umbilical cord blood transplantation for treatment of inherited metabolic diseases.
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RNA-Modified T Cells Mediate Effective Delivery of Immunomodulatory Cytokines to Brain Tumors.
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Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma.
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Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
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Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies.
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Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy.
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Standardization, workforce development and advocacy in cell and gene therapies: a summary of the 2020 Regenerative Medicine InterCHANGE.
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Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain.
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The (Pluri)Potential of Cell Therapy for Heart Failure.
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The (Translational) Road Less Traveled.
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The Landscape of Cell and Gene Therapies for Solid Tumors.
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The Role of Granulocyte Transfusions in Optimizing Candidacy for Chimeric Antigen Receptor T-cell Therapy in Patients With Treatment-refractory Infections.
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Therapy with Cardiomyocytes Derived from Pluripotent Cells in Chronic Chagasic Cardiomyopathy.