Cytochrome P-450 CYP1A2 Inhibitors

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  Subject Areas on Research

  • Fluvoxamine-theophylline interaction: gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2. 
  • Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. 
  • Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors.