Cytochrome P-450 CYP2A6

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  Subject Areas on Research

  • A preliminary analysis of interactions between genotype, retrospective ADHD symptoms, and initial reactions to smoking in a sample of young adults. 
  • Genome-wide association study of smoking behaviours in patients with COPD. 
  • Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4. 
  • Human halothane reduction in vitro by cytochrome P450 2A6 and 3A4: identification of low and high KM isoforms. 
  • Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. 
  • Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults. 
  • Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression. 
  • Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. 
  • Single-dose disulfiram does not inhibit CYP2A6 activity. 
  • Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity. 
  • The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans.