In Vitro Techniques

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  Subject Areas on Research

  • (+/-)-cis-2-acetoxycyclobutyltrimethylammonium iodide: a semirigid analogue of acetylcholine. 
  • (-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterization. 
  • (3H)-Propranolol binding sites in myocardial membranes: nonidentity with beta adrenergic receptors. 
  • 22Na+ and 86Rb+ transport in vascular smooth muscle of SHR, Wistar Kyoto, and Wistar rats. 
  • 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. 
  • 3H-Dopamine uptake by synaptic storage vesicles of rat whole brain and brain regions. 
  • 4-Fluorobenzylamine and phenylalanine methyl ester conjugates of 2-nitroimidazole: evaluation as hypoxic cell radiosensitizers. 
  • 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. 
  • 5-substituted derivatives of 6-halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-halogeno-3-((2-(S)-pyrrolidinyl)methoxy)pyridine with low picomolar affinity for alpha4beta2 nicotinic acetylcholine receptor and wide range of lipophilicity: potential probes for imaging with positron emission tomography. 
  • A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. 
  • A Phase I safety and immunogenicity trial of UBI microparticulate monovalent HIV-1 MN oral peptide immunogen with parenteral boost in HIV-1 seronegative human subjects. 
  • A bioluminescence method for the demonstration of regional glucose distribution in brain slices. 
  • A biomechanical comparative analysis of two techniques for tibiotalar arthrodesis. 
  • A circuit model for saccadic suppression in the superior colliculus. 
  • A comparative evaluation of the effects of multiple vasodilators on human internal mammary artery. 
  • A comparison using tissue electrical properties and temperature rise to determine relative absorption of microwave power in malignant tissue. 
  • A desensitized state of the beta adrenergic receptor not associated with high-affinity agonist occupancy. 
  • A dynamic intravascular artificial lung. 
  • A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia. 
  • A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization. 
  • A knotless flexor tendon repair technique using a bidirectional barbed suture: an ex vivo comparison of three methods. 
  • A leukocyte lipid up-regulates the avidity of lymphocyte function-associated antigen-1. 
  • A linear material model for fiber-induced anisotropy of the anulus fibrosus. 
  • A low-cost high-efficiency fiber-optic coupler for recording action potentials within the myocardial wall. 
  • A mathematical model for analysis of pharmacologically induced changes in the kinetics of cardiac muscle. 
  • A mechanism of paraquat toxicity involving nitric oxide synthase. 
  • A method of MRI-based thermal modelling for a RF phased array. 
  • A model for human medulloblastoma. Growth, morphology, and chromosomal analysis in vitro and in athymic mice. 
  • A model of ribonuclease based on chemical evidence. 
  • A modified host-cell reactivation assay to measure repair of alkylating DNA damage for assessing risk of lung adenocarcinoma. 
  • A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5. 
  • A mutation of the beta 2-adrenergic receptor impairs agonist activation of adenylyl cyclase without affecting high affinity agonist binding. Distinct molecular determinants of the receptor are involved in physical coupling to and functional activation of Gs. 
  • A new face on apoptosis: death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins. 
  • A new irreversibly inhibited form of xanthine oxidase from ethylisonitrile. 
  • A new nerve guide conduit material composed of a biodegradable poly(phosphoester). 
  • A new quantitative test for sperm penetration into cervical mucus. 
  • A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function. 
  • A nonparametric Bayesian modeling approach for cytogenetic dosimetry. 
  • A novel method for detection and ex vivo expansion of HIV type 1-specific cytolytic T lymphocytes. 
  • A novel method to assess platelet inhibition by eptifibatide with thrombelastograph. 
  • A novel process for optimizing musculoskeletal allograft tissue to improve safety, ultrastructural properties, and cell infiltration. 
  • A paclitaxel-loaded recombinant polypeptide nanoparticle outperforms Abraxane in multiple murine cancer models. 
  • A pentapeptide monocyte locomotion inhibitory factor protects brain ischemia injury by targeting the eEF1A1/endothelial nitric oxide synthase pathway. 
  • A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection. AIDS Vaccine Evaluation Group. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A proarrhythmic response to sodium channel blockade: modulation of the vulnerable period in guinea pig ventricular myocardium. 
  • A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA. 
  • A pumping artificial lung. 
  • A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data. 
  • A rapid capsaicin-activated current in rat trigeminal ganglion neurons. 
  • A receptor for the third component of complement in the human renal glomerulus. 
  • A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits. 
  • A role for the magnetic field in the radiation-induced efflux of calcium ions from brain tissue in vitro. 
  • A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA. 
  • A single integral finite strain viscoelastic model of ligaments and tendons. 
  • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. 
  • A small region of the beta-adrenergic receptor is selectively involved in its rapid regulation. 
  • A soluble inhibitor of T lymphocyte function induced by HIV-1 infection of CD4+ T cells: characterization of a cellular protein and its relationship to p15E. 
  • A stepless needle-dilator for expedient percutaneous catheterization: technical note. 
  • A surgical guide for identifying the lateral femoral circumflex vessels during free vascularized fibular transfer for avascular necrosis of the femoral head. 
  • A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo. 
  • A-band mass exceeds mass of its filament components by 30-45%. 
  • ATM binds to beta-adaptin in cytoplasmic vesicles. 
  • ATP receptor activation potentiates a voltage-dependent Ca channel in hippocampal neurons. 
  • Ability of epinephrine, but not increased extracellular calcium, to reverse the effects of verapamil on ventricular automaticity in vitro. 
  • Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway. 
  • Abnormal hyperexcitability of hippocampal slices from kindled rats is transient. 
  • Abnormal monocyte chemotaxis in patients with breast cancer: evidence for a tumor-mediated effect. 
  • Abnormal neuronal excitability in hippocampal slices from kindled rats. 
  • Abnormalities of carbohydrate and lipid metabolism in Dahl rats. 
  • Abnormalities of leukotaxis in atopic dermatitis. 
  • Abortive and productive infections of human mononuclear phagocytes by type I herpes simplex virus. 
  • Absence of a role of gamma-glutamyl transpeptidase in the transport of amino acids by rat renal brushborder membrane vesicles. 
  • Absence of metabolite formation during nitroglycerin-induced relaxation of isolated blood vessels. 
  • Absorption of paraquat and diquat from the airways of the perfused rat lung. 
  • Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinase. 
  • Acetylcholine promotes the proliferation and collagen gene expression of myofibroblastic hepatic stellate cells. 
  • Acetylenics. 2. Synthesis and pharmacology of certain N,N-diakyl-3-phenylpropyn-2-amines. Some analogues with tryptamine-like behavioral effects in mice. 
  • Acoustic radiation force impulse imaging on ex vivo abdominal aortic aneurysm model. 
  • Acrylamide and carbon disulfide treatments increase the rate of rat brain tubulin polymerization. 
  • Actin-associated neurabin-protein phosphatase-1 complex regulates hippocampal plasticity. 
  • Action potential broadening and frequency-dependent facilitation of calcium signals in pituitary nerve terminals. 
  • Actions of cholecystokinin-related peptides on the gallbladder of bony fishes in vitro. 
  • Activation by saccharides of a cation-selective pathway on canine lingual epithelium. 
  • Activation of EGF receptors mediates pulmonary vasoconstriction induced by residual oil fly ash. 
  • Activation of complement by endotoxin. 
  • Activation of human granulocytes by arachidonic acid: its use and limitations for investigating granulocyte functions. 
  • Activation of kappa opioid receptors by U50488H and morphine enhances the release of substance P from rat trigeminal nucleus slices. 
  • Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. 
  • Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor. 
  • Activation primes human B lymphocytes to respond to heat shock. 
  • Acute in vivo genetic rescue demonstrates that phosphorylation of RIM1alpha serine 413 is not required for mossy fiber long-term potentiation. 
  • Acute spinal ligament disruption: MR imaging with anatomic correlation. 
  • Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. 
  • Adaptive mechanisms that preserve cardiac function in mice without myoglobin. 
  • Adenosine A(3)-receptor stimulation attenuates postischemic dysfunction through K(ATP) channels. 
  • Adenylate cyclase-coupled beta adrenergic receptors effect of membrane lipid-perturbing agents on receptor binding and enzyme stimulation by catecholamines. 
  • Adhesion of fungi. 
  • Adrenal medullary storage vesicles of the spontaneously hypertensive rat. 
  • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. 
  • Age-associated differences in beta adrenergic-stimulated lipolysis in adipocytes from Sprague-Dawley and Fischer 344 rats. 
  • Age-related metabolic fatigue during low glucose conditions in rat hippocampus. 
  • Aging and dietary modulation of elastase and interleukin-1 beta secretion. 
  • Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood. 
  • Agonist-induced sensitization of beta-adrenoceptor signaling in neonatal rat heart: expression and catalytic activity of adenylyl cyclase. 
  • Agonist-specific alterations in receptor binding affinity associated with solubilization of turkey erythrocyte membrane beta adrenergic receptors. 
  • Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets. 
  • Agonist-specific effects of monovalent and divalent cations on adenylate cyclase-coupled alpha adrenergic receptors in rabbit platelets. 
  • Alpha 2-macroglobulin 'fast' forms inhibit superoxide production by activated macrophages. 
  • Alpha-adrenergic receptor subtypes. 
  • Alpha-crystallin, a molecular chaperone, forms a stable complex with carbonic anhydrase upon heat denaturation. 
  • Alpha2-adrenergic receptors in human dorsal root ganglia: predominance of alpha2b and alpha2c subtype mRNAs. 
  • Alteration of pulmonary neuroendocrine cells during epithelial repair of naphthalene-induced airway injury. 
  • Alterations in receptors for sensory neuropeptides in human inflammatory bowel disease. 
  • Alterations in serotonergic receptor expression in experimental vein grafts. 
  • Alterations in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage. 
  • Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis. 
  • Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites. 
  • Alveolar barrier function assessed by hydrophobic and hydrophilic fluorescent solutes in rabbit lung. 
  • Aminopyridines and sparteine as inhibitors of membrane potassium conductance: effects on Myxicola giant axons and the lobster neuromuscular junction. 
  • Amyloid-beta1-42 reduces neuronal excitability in mouse dentate gyrus. 
  • An N-terminal truncation of the ncd motor protein supports diffusional movement of microtubules in motility assays. 
  • An NMDA-mediated component of excitatory synaptic input to dentate granule cells in 'epileptic' human hippocampus studied in vitro. 
  • An approach to the study of G-protein-coupled receptor kinases: an in vitro-purified membrane assay reveals differential receptor specificity and regulation by G beta gamma subunits. 
  • An assay for alpha-adrenergic receptor subtypes using [3H]dihydroergocryptine. 
  • An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response. 
  • An in vitro study of horizontal connections in the intermediate layer of the superior colliculus. 
  • An in vitro system to evaluate the effects of ischemia on survival of cells used for cell therapy. 
  • An integrated indenter-ARFI imaging system for tissue stiffness quantification. 
  • An isolated perfused rat lung preparation. 
  • Analysis of calcium homeostasis in activated human polymorphonuclear leukocytes. Evidence for two distinct mechanisms for lowering cytosolic calcium. 
  • Analysis of protein binding to receptor-doped lipid monolayers by Monte Carlo simulation. 
  • Analysis of responses to serotonin in the pulmonary vascular bed of the cat. 
  • Analysis of short-term plasticity at the perforant path-granule cell synapse. 
  • Analysis of sites phosphorylated on acetyl-CoA carboxylase in response to insulin in isolated adipocytes. Comparison with sites phosphorylated by casein kinase-2 and the calmodulin-dependent multiprotein kinase. 
  • Analysis of tensile strength of tendon anastomosis. 
  • Analysis of the expression of CD5 by human B cells and correlation with functional activity. 
  • Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB. 
  • Anatomic validation of a novel method for left ventricular volume and mass measurements with use of real-time 3-dimensional echocardiography. 
  • Androgens and isolation from adult tutors differentially affect the development of songbird neurons critical to vocal plasticity. 
  • Androgens modulate NMDA receptor-mediated EPSCs in the zebra finch song system. 
  • Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis. 
  • Anisotropic analysis of multi-component T2 and T1ρ relaxations in achilles tendon by NMR spectroscopy and microscopic MRI. 
  • Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics. 
  • Anomalous equilibrium binding properties of high-affinity racemic radioligands. 
  • Anoxia induces phospholipase A2 activation in rabbit renal proximal tubules. 
  • Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells. 
  • Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells. 
  • Anti-inflammatory and anti-osteoporotic activities of base-boronated nucleosides and phosphate-boronated nucleotides in rodents. 
  • Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation. 
  • Antibody-conjugated gold-gold sulfide nanoparticles as multifunctional agents for imaging and therapy of breast cancer. 
  • Antibody-dependent enhancement of human immunodeficiency virus type 1 infection. 
  • Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2/neu) gene product p185. 
  • Anticonvulsant-like actions of baclofen in the rat hippocampal slice. 
  • Antiepileptic effects of GABAb receptor activation in area CA3 of rat hippocampus. 
  • Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. 
  • Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. 
  • Antithrombin affects hemostatic response to recombinant activated factor VII in factor VIII deficient plasma. 
  • Antitumor agents--CLI. Bis(helenalinyl)glutarate and bis(isoalantodiol-B)glutarate, potent inhibitors of human DNA topoisomerase II. 
  • Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Inhibition of glyoxalase I and induction of apoptosis. 
  • ApoE isoform affects LTP in human targeted replacement mice. 
  • Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis. 
  • Apolipoprotein E-derived peptides block alpha7 neuronal nicotinic acetylcholine receptors expressed in xenopus oocytes. 
  • Apportionment of the terminals from single preganglionic axons to target neurones in the rabbit ciliary ganglion. 
  • Arthroscopic debridement of the talonavicular joint using dorsomedial and dorsolateral portals: a cadaveric study of safety and access. 
  • Arthroscopic visualization of the posterior subtalar joint in the prone position: a cadaver study. 
  • Ascorbic acid effects on lens 86 rubidium transport. 
  • Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents. 
  • Aspirin-induced hemolysis: the role of concomitant oxidant (H2O2) challenge. 
  • Aspirin-triggered resolvin D1 prevents surgery-induced cognitive decline. 
  • Assessments of thrombogenicity by three in vitro techniques. Student Research Award in the Undergraduate, Master Candidate, or Health Science Degree Candidate Category, 21st annual meeting of the Society for Biomaterials, San Francisco, CA, March 18-22, 1995. 
  • Association of calmodulin and smooth muscle myosin light chain kinase: application of a label selection technique with trace acetylated calmodulin. 
  • Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. 
  • Attenuation of epileptiform bursting by baclofen: reduced potency in elevated potassium. 
  • Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E. 
  • Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway. 
  • Autoinhibition of casein kinase I epsilon (CKI epsilon) is relieved by protein phosphatases and limited proteolysis. 
  • Automated segmentation of the canine corpus callosum for the measurement of diffusion tensor imaging. 
  • Automating neurosurgical tumor resection surgery: Volumetric laser ablation of cadaveric porcine brain with integrated surface mapping. 
  • Autoradiographic localization of benzomorphan binding sites in rat brain. 
  • Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. 
  • Avidin-biotin interactions at vesicle surfaces: adsorption and binding, cross-bridge formation, and lateral interactions. 
  • Axon terminal hyperexcitability seen in epileptogenesis in vitro. 
  • BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair. 
  • BMP4 is essential for lens induction in the mouse embryo. 
  • BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways. 
  • Baclofen facilitates the development of long-term potentiation in the rat dentate gyrus. 
  • Baclofen has a proepileptic effect in the rat dentate gyrus. 
  • Baclofen selectively inhibits transmission at synapses made by axons of CA3 pyramidal cells in the hippocampal slice. 
  • Baclofen suppresses bursting activity induced in hippocampal slices by differing convulsant treatments. 
  • Baclofen suppresses hippocampal epileptiform activity at low concentrations without suppressing synaptic transmission. 
  • Bacteriophage T4 proteins replicate plasmids with a preformed R loop at the T4 ori(uvsY) replication origin in vitro. 
  • Balloon dilatation of excised aortic coarctations. 
  • Barbiturate effects on acetylcholine-activated channels in Aplysia neurons. 
  • Barbiturate-induced alterations in the kinetic parameters of slow outward current in Aplysia giant neurons. 
  • Barbiturate-induced slow outward currents in Aplysia neurones. 
  • Barbiturates: inhibition of sustained firing in Aplysia neurons. 
  • Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland. 
  • Beta cell monoamines: further evidence for their role in modulating insulin secretion. 
  • Beta-adrenergic receptors: recognition and regulation. 
  • Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. 
  • Biliary lithotripsy: in vitro analysis of gallstone fragmentation for equivalent stone volumes. 
  • Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1q. 
  • Binding of 3H-phenamil, an irreversible amiloride analog, to toad urinary bladder: effects of aldosterone and vasopressin. 
  • Binding of [125I]-N-(p-aminophenethyl)spiroperidol to the D-2 dopamine receptor in the neurointermediate lobe of the rat pituitary gland: a thermodynamic study. 
  • Binding of myosin subfragment 1 to glycerinated insect flight muscle in the rigor state. 
  • Binding sites for L-[3H]glutamate on hippocampal synaptic membranes: three populations differentially affected by chloride and calcium ions. 
  • Biochemical changes in rat testis during postnatal maturation. 
  • Biochemical characterization of the Ca2+ release channel of skeletal and cardiac sarcoplasmic reticulum. 
  • Biochemical evidence for enhanced sensitivity to N-methyl-D-aspartate in the hippocampal formation of kindled rats. 
  • Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel. 
  • Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring. 
  • Biological basis of in vitro tests of sperm function. 
  • Biological disposition of antibilharzial antimony drugs. II. Antimony fate and uptake by Schistosoma haematobium eggs in man. 
  • Biological evaluation of some biphenyl analogs of acetyl-seco-hemicholinium No. 3. 
  • Biological evaluation of some terphenyl analogs of hemicholinium No. 3. 
  • Biological magnetic resonance imaging using laser-polarized 129Xe. 
  • Biomechanical and functional testing of plate fixation devices for proximal phalangeal fractures. 
  • Biotinylated tags for recovery and characterization of ribonucleoprotein complexes. 
  • Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin. Evidence for two use-dependent binding sites. 
  • Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs. 
  • Blockade of nicotinic acetylcholine receptors suppresses hippocampal long-term potentiation in wild-type but not ApoE4 targeted replacement mice. 
  • Bombesin-like peptides and mast cell responses: relevance to bronchopulmonary dysplasia? 
  • Bombesin/GRP-preferring and neuromedin B-preferring receptors in the rat urogenital system. 
  • Both insulin and epidermal growth factor stimulate lipogenesis and acetyl-CoA carboxylase activity in isolated adipocytes. Importance of homogenization procedure in avoiding artefacts in acetyl-CoA carboxylase assay. 
  • Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. 
  • Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission. 
  • Brain cholecystokinin receptors. Binding characteristics, covalent cross-linking, and evolutionary aspects. 
  • Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. 
  • Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells. 
  • Bromodeoxyuridine-mediated radiosensitization in human glioma: the effect of concentration, duration, and fluoropyrimidine modulation. 
  • Bronchopulmonary inflammation and airway smooth muscle hyperresponsiveness induced by nitrogen dioxide in guinea pigs. 
  • C-fos mRNA induction in the central and peripheral nervous systems of diisopropyl phosphorofluoridate (DFP)-treated hens. 
  • C1q acts synergistically with phorbol dibutyrate to activate CR1-mediated phagocytosis by human mononuclear phagocytes. 
  • C3b generation is affected by the structure of the O-antigen polysaccharide in lipopolysaccharide from salmonellae. 
  • C3orf58, a novel paracrine protein, stimulates cardiomyocyte cell-cycle progression through the PI3K-AKT-CDK7 pathway. 
  • C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha. 
  • CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells. 
  • CD8(+)NKR-P1A (+)T cells preferentially accumulate in human liver. 
  • CR1-receptor recycling in phorbol ester-activated polymorphonuclear leucocytes. 
  • CT-based ballistic wound path identification and trajectory analysis in anatomic ballistic phantoms. 
  • CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells. 
  • CaMKII is essential for the proasthmatic effects of oxidation. 
  • CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation. 
  • CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. 
  • Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. 
  • Calcitonin stimulates maturation of mammalian growth plate cartilage. 
  • Calcium dependence of presynaptic calcium current and post-synaptic response at the squid giant synapse. 
  • Calcium, magnesium, and long-term recovery from hypoxia in hippocampal tissue slices. 
  • Calcium-activated inward spike after-currents in bursting neurone R15 of Aplysia. 
  • Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. 
  • Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. 
  • Capillary blood flow. 3. Deformable model cells compared to erythrocytes in vitro. 
  • Cardiac ejection fraction: phantom study comparing cine MR imaging, radionuclide blood pool imaging, and ventriculography. 
  • Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform. 
  • Cardiac rigor mortis in dogs. 
  • Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture. 
  • Catalytic autoantibodies against myelin basic protein (MBP) isolated from serum of autistic children impair in vitro models of synaptic plasticity in rat hippocampus. 
  • Cationic selectivity and competition at the sodium entry site in frog skin. 
  • Cell- and heparin-binding domains of the hexabrachion arm identified by tenascin expression proteins. 
  • Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to alpha-adrenergic agents. 
  • Cell-free heterologous desensitization of adenylyl cyclase in S49 lymphoma cell membranes mediated by cAMP-dependent protein kinase. 
  • Cellular electrophysiology of clofilium, a new antifibrillatory agent, in normal and ischemic canine Purkinje fibers. 
  • Cellular interactions in hemostasis. 
  • Cellular mechanisms which distinguish between hormone- and antihormone-activated estrogen receptor. 
  • Cellular processing of temporal information in medial vestibular nucleus neurons. 
  • Cellular regulation of the benzodiazepine/GABA receptor: arachidonic acid, calcium, and cerebral ischemia. 
  • Central hemodynamic effects of an oxytocin receptor antagonist (atosiban) in the isolated, perfused rat heart. 
  • Central regulation of photosensitive membrane turnover in the lateral eye of Limulus. I. Octopamine primes the retina for daily transient rhabdom shedding. 
  • Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice. 
  • Changes in extracellular calcium and magnesium and synaptic transmission in isolated mouse spinal cord. 
  • Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: effect of diazepam. 
  • Changes in the structure of calmodulin induced by a peptide based on the calmodulin-binding domain of myosin light chain kinase. 
  • Channel shutdown: a response of hippocampal neurons to adverse environments. 
  • Characterisation of adrenergic receptors in human ureter. 
  • Characteristics of Candida albicans adherence to mouse tissues. 
  • Characteristics of lysine uptake by isolated renal cortical tubule fragments from mature and immature dogs. 
  • Characterization and analysis of an apparent autophosphorylation of chicken gizzard myosin light chain kinase. 
  • Characterization of CD8(-) HLA class I/epitope tetrameric complexes binding T cells. 
  • Characterization of T cells expressing the gamma/delta antigen receptor in human renal allografts. 
  • Characterization of a composite injury model of severe lower limb bone and nerve trauma. 
  • Characterization of alpha 2-macroglobulin binding to human trabecular meshwork cells: presence of the alpha 2-macroglobulin signaling receptor. 
  • Characterization of an acquired inhibitor to coagulation factor V. Antibody binding to the second C-type domain of factor V inhibits the binding of factor V to phosphatidylserine and neutralizes procoagulant activity. 
  • Characterization of canine intestinal cholecystokinin-58 lacking its carboxyl-terminal nonapeptide. Evidence for similar post-translational processing in brain and gut. 
  • Characterization of cardiac A1 adenosine receptors by ligand binding and photoaffinity labeling. 
  • Characterization of excitatory amino acid receptors expressed by embryonic chick motoneurons in vitro. 
  • Characterization of functional human alpha 2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol. 
  • Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. 
  • Characterization of mediators of insulin action. 
  • Characterization of peptide YY receptors in rabbit colonic mucosa. 
  • Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants. 
  • Characterization of the binding epitope of the monoclonal antibody DMAb-1 to ganglioside GM2. 
  • Characterization of the effect of cocaine on catecholamine uptake by pregnant myometrium. 
  • Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. 
  • Characterization of the insulinotropic potency of polyunsaturated fatty acids. 
  • Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts. 
  • Characterization of the radioiodinated analogue of SCH 23390: in vitro and in vivo D-1 dopamine receptor binding studies. 
  • Characterizing stiffness of human prostates using acoustic radiation force. 
  • Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. 
  • Chemoattractant receptor affinity reflects its ability to transduce different biological responses. 
  • Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein. 
  • Chemoattractant-mediated stimulation of the respiratory burst in human polymorphonuclear leukocytes may require appearance of protein kinase activity in the cells' particulate fraction. 
  • Chiral inversion of the second generation IMiD CC-4047 (ACTIMID ) in human plasma and phosphate-buffered saline. 
  • Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus. 
  • Chloride-cotransport blockade desynchronizes neuronal discharge in the "epileptic" hippocampal slice. 
  • Chloroperoxidase-catalyzed halogenation of antipyrine, a drug substrate of liver microsomal cytochrome P-450. 
  • Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx. 
  • Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum. 
  • Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction. 
  • Cholecystokinin blocks some effects of kainic acid in CA3 region of hippocampal slices. 
  • Cholecystokinin excites interneurons in rat basolateral amygdala. 
  • Choline availability to the developing rat fetus alters adult hippocampal long-term potentiation. 
  • Cholinergic mechanisms involved with histamine hyperreactivity in immune rabbit airways challenged with ragweed antigen. 
  • Cholinergic stimulation of phosphatidic acid formation by rat cornea in vitro. 
  • Chronic morphine administration alters epinephrine uptake in rat adrenal storage vesicles. 
  • Circuit oxygenator contributes to extracorporeal membrane oxygenation-induced hemolysis. 
  • Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. 
  • Citrate and vitamin E blunt the shock wave-induced free radical surge in an in vitro cell culture model. 
  • Clara cells attenuate the inflammatory response through regulation of macrophage behavior. 
  • Clathrin-coated vesicle assembly polypeptides: physical properties and reconstitution studies with brain membranes. 
  • Clinical and in vitro studies of imatinib in advanced carcinoid tumors. 
  • Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey. 
  • Clot-blood contrast in fast gradient-echo magnetic resonance imaging. 
  • Cobalamin inhibition of HIV-1 integrase and integration of HIV-1 DNA into cellular DNA. 
  • Cocaine and beta-adrenergic receptor function in pregnant myometrium. 
  • Cocaine augments contractility of the pregnant human uterus by both adrenergic and nonadrenergic mechanisms. 
  • Cocaine blocks extraneuronal uptake of norepinephrine by the pregnant human uterus. 
  • Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium. 
  • Collagenolytic activity of synovium in rheumatoid arthritis. 
  • Collagenolytic activity of the skin associated with neuromuscular diseases including amyotrophic lateral sclerosis. 
  • Combining patch-clamp and optical methods in brain slices. 
  • Commitment to cell death is signaled by the appearance of a terminin protein of 30 kDa. 
  • Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum. 
  • Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish. 
  • Comparative strengths and structural properties of the upper and lower cervical spine in flexion and extension. 
  • Comparison of human and rat hepatocyte metabolism and mutagenic activation of 2-acetylaminofluorene. 
  • Comparison of human eosinophil and neutrophil adhesion to endothelial cells under nonstatic conditions. Role of L-selectin. 
  • Comparison of in vitro ischemia-induced disturbances in energy metabolism and protein synthesis in the hippocampus of rats and gerbils. 
  • Comparison of relaxation responses to multiple vasodilators in TxA(2)-analog and endothelin-1-precontracted pulmonary arteries. 
  • Comparison of streptokinase, urokinase, and recombinant tissue plasminogen activator in an in vitro model of venous thrombolysis. 
  • Comparison of the ACL and ACL graft forces before and after ACL reconstruction: an in-vitro robotic investigation. 
  • Comparison of the effect of polymethylmethacrylate and silicone intraocular lenses on rabbit corneal endothelium in vitro. 
  • Comparison of ultrasonography and oral cholecystography in lithotripsy. II. Determining retreatment. 
  • Comparisons of mixed leukocyte reactions with skin graft survival in families genotyped for HL-A. 
  • Complement-mediated vasoconstriction and graft rejection. 
  • Compressibility of perfused passive myocardium. 
  • Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration. 
  • Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model. 
  • Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat. 
  • Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA. 
  • Concomitant development of [3H]-dopamine and [3H]-5-hydroxytryptamine uptake systems in rat brain regions. 
  • Conditional dicentric chromosomes in yeast. 
  • Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused. 
  • Consequences of chemical modifications on the free radical reactions of human hemoglobin. 
  • Consequences of growth hormone deficiency on cardiac structure, function, and beta-adrenergic pathway: studies in mutant dwarf rats. 
  • Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms. 
  • Contribution of superficial layer neurons to premotor bursts in the superior colliculus. 
  • Control of cholecystokinin receptor dephosphorylation in pancreatic acinar cells. 
  • Control of microtubule assembly-disassembly by calcium-dependent regulator protein. 
  • Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. 
  • Correlation between function and structure in "epileptic" human hippocampal tissue maintained in vitro. 
  • Correlation of endoscopic optical coherence tomography with histology in the lower-GI tract. 
  • Correspondence of low mean shear and high harmonic content in the porcine iliac arteries. 
  • Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. 
  • Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go. 
  • Covalent labeling of the beta-adrenergic ligand-binding site with para-(bromoacetamidyl)benzylcarazolol. A highly potent beta-adrenergic affinity label. 
  • Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction. 
  • Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation. 
  • Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. 
  • Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells. 
  • Cyclic loading alters biomechanical properties and secretion of PGE2 and NO from tendon explants. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • Cyclosporine augments receptor-mediated cellular Ca2+ fluxes in isolated hepatocytes. 
  • Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation. 
  • Cytokine profiles in seronegative volunteers immunized with a recombinant canarypox and gp120 prime-boost HIV-1 vaccine. NIAID AIDS Vaccine Evaluation Group. 
  • DNA methylation alterations in response to pesticide exposure in vitro. 
  • DNA nanotubes self-assembled from triple-crossover tiles as templates for conductive nanowires. 
  • DNA polymerase arrest by adducted trivalent chromium. 
  • DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. 
  • Decay-accelerating factor is present on paroxysmal nocturnal hemoglobinuria erythroid progenitors and lost during erythropoiesis in vitro. 
  • Decreased expression of tissue inhibitor of metalloproteinase 1 in stunned myocardium. 
  • Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease. 
  • Defective cellular immunity associated with chronic mucocutaneous moniliasis and recurrent staphylococcal botryomycosis: immunological reconstitution by allogeneic bone marrow. 
  • Defective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient mice. 
  • Deformation and flow of membrane into tethers extracted from neuronal growth cones. 
  • Degradation of 14C-labeled streptococcal cell walls by egg white lysozyme and lysosomal enzymes. 
  • Delayed apoptosis of circulating neutrophils in Kawasaki disease. 
  • Delta 9-tetrahydrocannabinol suppression of prolactin secretion in the rat: lack of direct pituitary effect. 
  • Delta-opioid-receptor activation by [D-Pen2,D-Pen5]enkephalin and morphine inhibits substance P release from trigeminal nucleus slices. 
  • Dendritic properties of hippocampal CA1 pyramidal neurons in the rat: intracellular staining in vivo and in vitro. 
  • Deoxycholate induces the preferential hydrolysis of polyphosphoinositides by human platelet and rat corneal phospholipase C. 
  • Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury. 
  • Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation. 
  • Depression of glutamate-mediated synaptic transmission by benzyl alcohol. 
  • Design and evaluation of a new, low pressure loss, implantable artificial lung. 
  • Design of tenofovir-UC781 combination microbicide vaginal gels. 
  • Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates. 
  • Determination of subtype selectivity of alpha-adrenergic antagonists: comparison of selective and nonselective radioligands. 
  • Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration. 
  • Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. 
  • Development of a new technique for reducing pressure pulse generation during 308-nm excimer laser coronary angioplasty. 
  • Development of an animal model of acetabular fractures. 
  • Development of an experimental system for the study of urethral biomechanical function. 
  • Development of dopamine neurotransmission and uptake inhibition in the caudate nucleus as measured by fast-cyclic voltammetry. 
  • Development of peptide antagonists for the androgen receptor using combinatorial peptide phage display. 
  • Developmental differences in the sensitivity of hippocampal GABAA receptor-mediated IPSCS to ethanol. 
  • Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung. 
  • Developmental increase in the sensitivity to magnesium of NMDA receptors on CA1 hippocampal pyramidal cells. 
  • Diazepam promotes ATP recovery and prevents cytochrome c release in hippocampal slices after in vitro ischemia. 
  • Dicoumarol-sensitive NADPH: phenanthrenequinone oxidoreductase in channel catfish (Ictalurus punctatus). 
  • Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. 
  • Differences in the absorption, metabolism and biliary excretion of a diastereomeric pair of alphavbeta3-antagonists in rat: limited role of P-glycoprotein. 
  • Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis. 
  • Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei. 
  • Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation. 
  • Differential collagen I gene expression in fetal fibroblasts. 
  • Differential effect of HERG blocking agents on cardiac electrical alternans in the guinea pig. 
  • Differential effect of cyclic adenosine monophosphate on the secretion of human placental lactogen and human chorionic gonadotropin. 
  • Differential effects of phenobarbital and pentobarbital on stimulus train-induced bursting in the hippocampal slice. 
  • Differential isoform-specific regulation of calcium-independent protein kinase C in rat cerebral cortex. 
  • Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain. 
  • Differential metabolism of O-ethyl O-4-nitrophenyl phenylphosphonothioate by rat and chicken hepatic microsomes. 
  • Differential roles of Aβ processing in hypoxia-induced axonal damage. 
  • Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. 
  • Differential secretion of proLHRH fragments in response to [K+], prostaglandin E2 and C kinase activation. 
  • Differential sensitivity of GABA A receptor-mediated IPSCs to cannabinoids in hippocampal slices from adolescent and adult rats. 
  • Differential sensitivity of hippocampal interneurons to ethanol in adolescent and adult rats. 
  • Differential wiring of local excitatory and inhibitory synaptic inputs to islet cells in rat spinal lamina II demonstrated by laser scanning photostimulation. 
  • Diffusion tensor imaging findings suggestive of white matter alterations in a canine model of mucopolysaccharidosis type I. 
  • Diffusional anisotropy in collagenous tissues: fluorescence imaging of continuous point photobleaching. 
  • Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. 
  • Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras. 
  • Direct evidence that coronary perfusion affects diastolic myocardial mechanical properties in canine heart. 
  • Direct measurement of the Poisson's ratio of human patella cartilage in tension. 
  • Direct observation of substance P-induced internalization of neurokinin 1 (NK1) receptors at sites of inflammation. 
  • Discrimination of post- and presynaptic GABAB receptor-mediated responses by tetrahydroaminoacridine in area CA3 of the rat hippocampus. 
  • Disinhibition in rat superior colliculus mediated by GABAc receptors. 
  • Disorders of cell volume regulation. I. Effects of inhibition of plasma membrane adenosine triphosphatase with ouabain. 
  • Dispersion of latencies in photoreceptors of Limulus and the adapting-bump model. 
  • Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins. 
  • Dissociation between aggregation and superoxide production in human granulocytes. 
  • Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity. 
  • Distinct DNA targets for trans-activation by HTLV-1 tax and adenovirus E1A. 
  • Distinct contributions of small and large conductance Ca2+-activated K+ channels to rat Purkinje neuron function. 
  • Distinct electric potentials in soma and neurite membranes. 
  • Distinction between alkaline phosphatase and Mg2+-ATPase of the human polymorphonuclear leukocyte. 
  • Distribution of bronchoconstrictor responses in isolated-perfused rat lung. 
  • Diversity in membrane binding sites of ankyrins. Brain ankyrin, erythrocyte ankyrin, and processed erythrocyte ankyrin associate with distinct sites in kidney microsomes. 
  • Do antagonists of pancreatic cholecystokinin receptors interact with central nervous system cholecystokinin receptors? 
  • Domain unfolding plays a role in superfibronectin formation. 
  • Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. 
  • Dopamine efflux during withdrawal from continuous or intermittent cocaine. 
  • Dopamine receptor of the porcine anterior pituitary gland. Effects of N-ethylmaleimide and heat on ligand binding mimic the effects of guanine nucleotides. 
  • Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists. 
  • Dopamine release and uptake are greater in female than male rat striatum as measured by fast cyclic voltammetry. 
  • Dopamine-sensitive adenylate cyclase: antagonism by impiramine and its analogues. 
  • Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms. 
  • Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. 
  • Drosophila RNA polymerase II mutants that affect transcription elongation. 
  • Drug-resistant effect of adenine nucleotides and magnesium on catecholamine efflux from isolated adrenal medullary storage vesicles. 
  • Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase. 
  • Dual actions of S-nitrosylated derivative of vasoactive intestinal peptide as a vasoactive intestinal peptide-like mediator and a nitric oxide carrier. 
  • Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors. 
  • Dual-energy micro-CT of the rodent lung. 
  • Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies. 
  • Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heart. 
  • Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure. 
  • Dynorphin A increases substance P release from trigeminal primary afferent C-fibers. 
  • E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. 
  • EFFECTS OF LOW-INTENSITY MICROWAVES ON ISOLATED NEURONS. 
  • ELISA for quantitation of L-selectin shed from leukocytes in vivo. 
  • ELISA-quantitation of phosphorylated tau protein in the Alzheimer's disease brain. 
  • Edge targeting reduces the number of shock waves required for biliary ESWL in vitro. 
  • Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats. 
  • Effect of FSH on protein biosynthesis in testes of the immature rat. 
  • Effect of acid predissolution on fibril size and fibril flexibility of synthetic beta-amyloid peptide. 
  • Effect of antibiotics on the in vitro incorporation of acetate-14C into intestinal lipids. 
  • Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat. 
  • Effect of brief myocardial ischemia on sympathetic coronary vasoconstriction. 
  • Effect of cellular senescence on the P2Y-receptor mediated calcium response in trabecular meshwork cells. 
  • Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. 
  • Effect of chemotherapy on uptake of alkali metals by experimental tumors. 
  • Effect of cooling on the responsiveness of canine tracheal muscle. 
  • Effect of cyclic adenosine 3',5'-monophosphate on the incorporation of 3H-leucine into polypeptides by beef thyroid polysomes in vitro. 
  • Effect of cyclooxygenase inhibitors and protease inhibitors on phorbol-induced stimulation of oxygen consumption and superoxide production by rat pulmonary macrophages. 
  • Effect of cyclosporine on bile secretion in rats. 
  • Effect of cystine loading on substrate oxidation by rat renal tubules. 
  • Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. 
  • Effect of dihydrostreptomycin on tissue lipid of guinea-pigs. 
  • Effect of excess magnesium on vagal inhibition and acetylcholine sensitivity of the mammalian heart in situ and in vitro. 
  • Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. 
  • Effect of helium and heliox on glutamate decarboxylase activity. 
  • Effect of high-energy X-ray irradiation on creep mechanisms in bone and dentin. 
  • Effect of kindling on potassium-induced electrographic seizures in vitro. 
  • Effect of magnesium sulfate on contractile force and intracellular calcium concentration in pregnant human myometrium. 
  • Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction. 
  • Effect of membrane fluidizers on the number and affinity of chemotactic factor receptors on human polymorphonuclear leukocytes. 
  • Effect of methyl phenyldiazenecarboxylate (azoester) on lens membrane function. 
  • Effect of oxygen at high pressure on spontaneous transmitter release. 
  • Effect of pH on the microhardness of renal calculi. 
  • Effect of pentoxifylline on the flow of polymorphonuclear leukocytes through a model capillary. 
  • Effect of platelet-activating factor on hepatic capillary pressure in isolated dog liver. 
  • Effect of prostaglandin E 1 on leukocyte migration. 
  • Effect of proteolytic enzyme inhibitors on contractile responses of the aortic strip. 
  • Effect of sera from myasthenia gravis patients on acetylcholine receptors in myotube cultures. 
  • Effect of sevoflurane on P50 and on measurement of oxygen tension. 
  • Effect of substance P on neurally mediated contraction of rabbit airway smooth muscle. 
  • Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy. 
  • Effect of the posterior cruciate ligament on posterior stability of the knee in high flexion. 
  • Effect of vasopressin and serosal hypertonicity on toad urinary bladder. 
  • Effects of 5-fluorouracil on erythrocytes in relation to its cardiotoxicity: membrane structure and functioning. 
  • Effects of 9, 12, 15-octadecatrien-6-ynoic acid on the metabolism of arachidonic acid in platelets and on platelet aggregation. 
  • Effects of 9,12,15-octadecatrien-6-ynoic acid on the metabolism of arachidonic acid in platelets and on the platelet aggregation. 
  • Effects of ELF (1-120 Hz) and modulated (50 Hz) RF fields on the efflux of calcium ions from brain tissue in vitro. 
  • Effects of ELF fields on calcium-ion efflux from brain tissue in vitro. 
  • Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. 
  • Effects of amiloride on pH regulation in canine cardiac Purkinje fibers. 
  • Effects of baclofen on synaptically-induced cell firing in the rat hippocampal slice. 
  • Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia. 
  • Effects of chemical group specific reagents on sodium entry and the amiloride binding site in frog skin: evidence for separate sites. 
  • Effects of colchicine and cytochalasin B on hypertonicity-induced changes in toad urinary bladder. 
  • Effects of delay in administration of potassium cardioplegia to the isolated rat heart. 
  • Effects of distention and short-term grafting on vasoreactivity in rabbit external jugular veins. 
  • Effects of droperidol on depolarization-induced automaticity, maximum upstroke velocity (Vmax) and the kinetics of recovery of Vmax in guinea-pig ventricular myocardium. 
  • Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: beta-adrenergic receptor coupling to Gs regulatory protein. 
  • Effects of gamma hydroxybutyric acid on inhibition and excitation in rat neocortex. 
  • Effects of glucose deficiency on glutamate/aspartate release and excitatory synaptic responses in the hippocampal CA1 area in vitro. 
  • Effects of human growth hormone on immune functions: in vitro studies on cells of normal and growth hormone-deficient children. 
  • Effects of human immunodeficiency virus type 1 on CD4 lymphocyte subset activation. 
  • Effects of hypertonia on voltage-gated ion currents in freshly isolated hippocampal neurons, and on synaptic currents in neurons in hippocampal slices. 
  • Effects of in vivo and in vitro production of lactic acid on ionized, protein-bound, and complex-bound calcium in blood. 
  • Effects of local anesthetics on guanyl nucleotide modulation of the catecholamine-sensitive adenylate cyclase system and on beta-adrenergic receptors. 
  • Effects of maternal nicotine exposure on branching morphogenesis of mouse fetal lung: in vivo and in vitro studies. 
  • Effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice. 
  • Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells. 
  • Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle. 
  • Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure. 
  • Effects of pulse strength and pulse duration on in vitro DNA electromobility. 
  • Effects of red and blue light on the growth and morphogenesis of Acetabularia crenulata. 
  • Effects of relative hypoglycemia on LTP and NADH imaging in rat hippocampal slices. 
  • Effects of repetitive motion on human fibroblasts. 
  • Effects of reserpine on the adrenal medulla of the spontaneously hypertensive rat. 
  • Effects of reserpine on the content and properties of rat adrenal medullary storage vesicles. 
  • Effects of specific activity on meta-[(131)I]iodobenzylguanidine kinetics in isolated rat heart. 
  • Effects of temperature on cholinergic contractility of rabbit airway muscle. 
  • Effects of titanium particle size on osteoblast functions in vitro and in vivo. 
  • Effects of transient forebrain ischemia in area CA1 of the gerbil hippocampus: an in vitro study. 
  • Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. 
  • Effects of water exchange on the measurement of myocardial perfusion using paramagnetic contrast agents. 
  • Efficacy of recombinant human manganese superoxide dismutase compared to allopurinol in protection of ischemic skeletal muscle against "no-reflow". 
  • Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism. 
  • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. 
  • Elastic deformation and failure of lipid bilayer membranes containing cholesterol. 
  • Electric fields in tumors exposed to external voltage sources: implication for electric field-mediated drug and gene delivery. 
  • Electrical characteristics of dendrites and dendritic spines in intracellularly stained CA3 and dentate hippocampal neurons. 
  • Electron microscopic alterations in experimental pulmonary hypertension. 
  • Electron paramagnetic resonance and potentiometric studies of arsenite interaction with the molybdenum centers of xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: a specific stabilization of the molybdenum(V) oxidation state. 
  • Electrophysiological and biochemical characteristics of Gymnodinium breve toxins. 
  • Electrophysiological correlates of secretion in normal human parathyroid cells. 
  • Electrophysiological effects of sulfinpyrazone on canine cardiac Purkinje fibers. 
  • Electrophysiology of methyl mercury poisoning. 
  • Electroporation and shock-induced transmembrane potential in a cardiac fiber during defibrillation strength shocks. 
  • Elemental microanalysis of organelles in proximal tubules. I. Alterations in transport and metabolism. 
  • Elemental microanalysis of organelles in proximal tubules. II. Effects of oxygen deprivation. 
  • Elementary response of olfactory receptor neurons to odorants. 
  • Elementary steps in the reaction mechanism of chicken liver fatty acid synthase: reduced nicotinamide adenine dinucleotide phosphate binding and formation and reduction of acetoacetyl-enzyme. 
  • Elevated Plasma B-Type Natriuretic Peptide Concentrations Directly Inhibit Circulating Neprilysin Activity in Heart Failure. 
  • Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia. 
  • Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic risk. 
  • Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. 
  • Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. 
  • Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). 
  • Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect. 
  • Endogenous opioids regulate long-term potentiation of synaptic inhibition in the dentate gyrus of rat hippocampus. 
  • Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia. 
  • Endothelin activates voltage-dependent Ca2+ current by a G protein-dependent mechanism in rabbit cardiac myocytes. 
  • Endothelin-1 selectively contracts portal vein through both ETA and ETB receptors in isolated rabbit liver. 
  • Endothelium modulation of the effects of nitroglycerin on blood vessels from dogs with pacing-induced heart failure. 
  • Endothelium-dependent relaxations in canine coronary arteries are enhanced in early heart failure and persist in recovery. 
  • Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells. 
  • Enhanced T2 contrast for MR histology of the mouse brain. 
  • Enhanced adenylate cyclase activity of turkey erythrocytes following treatment with beta-adrenergic receptor antagonists. 
  • Enhanced neutrophil chemiluminescence in familial Mediterranean fever. 
  • Enhanced oxygen delivery induced by perfluorocarbon emulsions in capillary tube oxygenators. 
  • Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. 
  • Enhanced receptor-cyclase coupling and augmented catecholamine-stimulated lipolysis in exercising rats. 
  • Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus. 
  • Enhancement of cardiac function by cyclocreatine in models of cardiopulmonary bypass. 
  • Enhancement of persistent sodium current by internal fluorescence in isolated hippocampal neurons. 
  • Enhancing melanoma treatment with resveratrol. 
  • Enkephalin analogues depress synaptic potentials in rat dentate granule cells recorded intracellularly in vitro. 
  • Enzymatic modification of proteins with a geranylgeranyl isoprenoid. 
  • Epidermal growth factor alters metabolism of inositol lipids and activity of protein kinase C in mouse embryo palate mesenchyme cells. 
  • Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice. 
  • Epinephrine induces rapid deterioration in pulmonary oxygen exchange in intact, anesthetized rats: a flow and pulmonary capillary pressure-dependent phenomenon. 
  • Epitope-specific signaling through CD45 on T lymphocytes leads to cAMP synthesis in monocytes after ICAM-1-dependent cellular interaction. 
  • Equalizing the electric field intensity within chick brain immersed in buffer solution at different carrier frequencies. 
  • Erosion of microbicide formulation coating layers: effects of contact and shearing with vaginal fluid or semen. 
  • Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury. 
  • Erythropoietin improves synaptic transmission during and following ischemia in rat hippocampal slice cultures. 
  • Estimation of cardiac conduction velocities using small data sets. 
  • Estradiol enhances long term potentiation in hippocampal slices from aged apoE4-TR mice. 
  • Estrogen blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries(1,2). 
  • Ethacrynic acid: acute hemodynamic effects and influence on the in vivo and in vitro response to nitroglycerin in the dog. 
  • Ethanol diminishes a voltage-dependent K+ current, the M-current, in CA1 hippocampal pyramidal neurons in vitro. 
  • Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons. 
  • Ethanol inhibition of NMDA mediated depolarizations is increased in the presence of Mg2+. 
  • Ethanol inhibits release of excitatory amino acids from slices of hippocampal area CA1. 
  • Ethanol promotes hydrolysis of 3H-labeled sialoconjugates from brain of mice in vitro. 
  • Ethanol reverses the direction of long-term synaptic plasticity in the dorsomedial striatum. 
  • Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes. 
  • Evaluation of 133Xe techniques for measurement of regional ventilation. 
  • Evaluation of a cytocentrifuge method for measuring neutrophil granulocyte chemotaxis. 
  • Evaluation of a dual-arm Archimedean spiral array for microwave hyperthermia. 
  • Evaluation of a novel kallikrein inhibitor on hemostatic activation in vitro. 
  • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. 
  • Evaluation of collagen modification and surface properties of a bovine artery via polyepoxy compound fixation. 
  • Evaluation of in vitro susceptibility of dermatophytes to oral antifungal agents. 
  • Evaluation of synchronous twin pulse technique for shock wave lithotripsy: determination of optimal parameters for in vitro stone fragmentation. 
  • Evaluation of the force-frequency relationship as a descriptor of the inotropic state of canine left ventricular myocardium. 
  • Evidence for depression of nuclear protein synthesis and concomitant stimulation of nuclear RNA synthesis during early estrogen action. 
  • Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. 
  • Evidence for susceptibility of intrathymic T cell precursors to human immunodeficiency virus infection: a mechanism for T4 (CD4) lymphocyte depletion. 
  • Evidence for the function of hyperactivated motility in sperm. 
  • Evidence that CCK-58 has structure that influences its biological activity. 
  • Evidence that activation of acetyl-CoA carboxylase by insulin in adipocytes is mediated by a low-Mr effector and not by increased phosphorylation. 
  • Evidence that forskolin binds to the glucose transporter of human erythrocytes. 
  • Evidence that toluene diisocyanate activates the efferent function of capsaicin-sensitive primary afferents. 
  • Ex vivo characterization of human anti-porcine hyperacute cardiac rejection. 
  • Ex-vivo ureteroscopy at the time of live donor nephrectomy. 
  • Excitation sequences of the atrial septum and the AV node in isolated hearts of the dog and rabbit. 
  • Excitatory and inhibitory circuitry in the superficial gray layer of the superior colliculus. 
  • Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami. 
  • Exogenously administered growth hormone and insulin-like growth factor-I alter intracellular Ca2+ handling and enhance cardiac performance. In vitro evaluation in the isolated isovolumic buffer-perfused rat heart. 
  • Expansion/deletion of mature T cells exposed to endogenous superantigens in vivo. 
  • Experimental determination of wall shear rate in canine carotid arteries perfused in vitro. 
  • Exploring the superior colliculus in vitro. 
  • Export by red blood cells of nitric oxide bioactivity. 
  • Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel. 
  • Expression of RNAs for calmodulin, actins, and tubulins in rat testis cells. 
  • Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers. 
  • Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance. 
  • Expression of extracellular glutathione peroxidase in human and mouse gastrointestinal tract. 
  • Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture. 
  • Extracellular chloride and the maintenance of spontaneous epileptiform activity in rat hippocampal slices. 
  • Extracellular lipid deposition in atherosclerosis. 
  • Extracellular mass transport considerations for space flight research concerning suspended and adherent in vitro cell cultures. 
  • Extracellular pH modulates block of both sodium and calcium channels by nicardipine. 
  • Extracellular potentials and currents of a single active fiber in a restricted volume conductor. 
  • Extracorporeal shock wave lithotripsy: the use of chemical treatments for improved stone comminution. 
  • Extreme hyperimmunoglobulinemia E and undue susceptibility to infection. 
  • Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits. 
  • Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity. 
  • Facile synthesis of site-specifically acetylated and methylated histone proteins: reagents for evaluation of the histone code hypothesis. 
  • Facilitation of granule cell epileptiform activity by mossy fiber-released zinc in the pilocarpine model of temporal lobe epilepsy. 
  • Facilitation of the induction of long-term potentiation by GABAB receptors. 
  • Facilitatory effects of 4-aminopyridine on neuromuscular transmission in disease states. 
  • Facilitatory effects of 4-aminopyridine on normal neuromuscular transmission. 
  • Factor analytic models of clustered multivariate data with informative censoring. 
  • Factors from saliva and oral bacteria, chemotactic for polymorphonuclear leukocytes: their possible role in gingival inflammation. 
  • Failure to detect a DNA repair-related defect in the transfection of ataxia-telangiectasia cells by enzymatically restricted plasmid. 
  • Familial polycythemia due to truncations of the erythropoietin receptor. 
  • Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. 
  • Feed-forward inhibitory potentials and excitatory interactions in guinea-pig hippocampal pyramidal cells. 
  • Fertilization and in vitro development of cryopreserved human prophase I oocytes. 
  • Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling. 
  • Fetal fibroblast contraction of collagen matrices in vitro: the effects of epidermal growth factor and transforming growth factor-beta. 
  • Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. 
  • Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model. 
  • Finite-element analysis of temperature rise and lesion formation from catheter ultrasound ablation transducers. 
  • Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins. 
  • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. 
  • Fluctuation-driven directional flow in biochemical cycle: further study of electric activation of Na,K pumps. 
  • Fluorescence changes on contractile activation in TnC(DANZ) labeled skinned rabbit psoas fibers. 
  • Fluorescence imaging of changes in intracellular chloride in living brain slices. 
  • Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons. 
  • Focused ultrasound (HIFU) induces localized enhancement of reporter gene expression in rabbit carotid artery. 
  • Forearm compartment pressures: an in vitro analysis of open and endoscopic assisted fasciotomy. 
  • Frame rate considerations for real-time abdominal acoustic radiation force impulse imaging. 
  • Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta. 
  • Frequency-dependent response of the vascular endothelium to pulsatile shear stress. 
  • Functional analysis of myocardial performance in murine hearts overexpressing the human beta 2-adrenergic receptor. 
  • Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves. 
  • Functional association of the parkin gene promoter with idiopathic Parkinson's disease. 
  • Functional characterization of two S-nitroso-L-cysteine transporters, which mediate movement of NO equivalents into vascular cells. 
  • Functional coupling of oxygen binding and vasoactivity in S-nitrosohemoglobin. 
  • Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). 
  • Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro. 
  • Functional implications of On-Off response variation in frog retinal ganglion cells. 
  • Functional inactivation and structural disruption of human alpha 2-macroglobulin by neutrophils and eosinophils. 
  • Functional mapping and Ca2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons. 
  • Functional organization of the Bel-1 trans activator of human foamy virus. 
  • Functional reconstitution of purified human Hv1 H+ channels. 
  • Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. 
  • Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression. 
  • Fungicidal versus fungistatic activity of terbinafine and itraconazole: an in vitro comparison. 
  • Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site. 
  • Future alternatives to heparin: low-molecular-weight heparin and hirudin. 
  • GABA transporters regulate a standing GABAC receptor-mediated current at a retinal presynaptic terminal. 
  • GABAA alpha 2 mRNA levels are decreased following induction of spontaneous epileptiform discharges in hippocampal-entorhinal cortical slices. 
  • GABAB-Receptor-mediated currents in interneurons of the dentate-hilus border. 
  • GABAB-receptor-mediated inhibition of the N-methyl-D-aspartate component of synaptic transmission in the rat hippocampus. 
  • GSK3 involvement in amylin signaling in isolated rat soleus muscle. 
  • Galactose and glucose metabolism in the isolated perfused suckling and adult rat liver. 
  • Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. 
  • Gender difference in smoking effect on chromosome sensitivity to gamma radiation in a healthy population. 
  • Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. 
  • Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat. 
  • Gene therapy for human bypass grafts. 
  • Generation of a fibroblast chemotactic factor in serum by activation of complement. 
  • Generation of dendritic cells in vitro from peripheral blood mononuclear cells with granulocyte-macrophage-colony-stimulating factor, interleukin-4, and tumor necrosis factor-alpha for use in cancer immunotherapy. 
  • Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas. 
  • Generation of nuclease resistant circular RNA decoys for HIV-Tat and HIV-Rev by autocatalytic splicing. 
  • Genesis of the monophasic action potential: role of interstitial resistance and boundary gradients. 
  • Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function. 
  • Genetic recombination of poliovirus in a cell-free system. 
  • Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons. 
  • Glial cell line-derived neurotrophic factor administration in postnatal life results in motor unit enlargement and continuous synaptic remodeling at the neuromuscular junction. 
  • Glial fibrillary acidic protein synthesized in vitro using messenger RNA from a human glioma cell line. 
  • Glucagon-like peptide 2 enhances intestinal epithelial restitution. 
  • Glutamate as transmitter of hippocampal perforant path. 
  • Glutamine can enhance synaptic transmission in hippocampal slices. 
  • Glutathione reductases from a variety of sources are inhibited by physiological levels of glutathione. 
  • Glutathione-mediated preservation and enhancement of isolated perifused islet function. 
  • Glycine metabolism. I. Properties of the system catalyzing the exchange of bicarbonate with the carboxyl group of glycine in Peptococcus glycinophilus. 
  • Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes. 
  • Graft hyporeactivity induced by immature donor-derived dendritic cells. 
  • Granulocyte-macrophage colony-stimulating factor and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes, and their precursors. 
  • Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. 
  • Group index of the human cornea at 1.3-microm wavelength obtained in vitro by optical coherence domain reflectometry. 
  • Growth arrest of human B lymphocytes is accompanied by induction of the low molecular weight mammalian heat shock protein (Hsp28). 
  • Growth factor-mediated phosphorylation of proapoptotic BAD reduces tubule cell death in vitro and in vivo. 
  • Growth hormone attenuates early left ventricular remodeling and improves cardiac function in rats with large myocardial infarction. 
  • Guanine nucleotides and alpha 1 adrenergic receptors in the heart. 
  • H(2)O(2)-induced O(2) production by a non-phagocytic NAD(P)H oxidase causes oxidant injury. 
  • HDAC6 modulates cell motility by altering the acetylation level of cortactin. 
  • HIV-1 sensitivity to zidovudine and clinical outcome in children. 
  • HIV-inducing factor in cervicovaginal secretions is associated with bacterial vaginosis in HIV-1-infected women. 
  • HLA class II molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway. 
  • Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage. 
  • Halogenated phenolic contaminants inhibit the in vitro activity of the thyroid-regulating deiodinases in human liver. 
  • Halogenated pyrimidine sensitization of low dose rate irradiation in human malignant glioma. 
  • Helix-loop-helix transcription factors E12 and E47 are not essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis. 
  • Hemoglobins of Boa constrictor amarali. 
  • Hemolytic characteristics of three commercially available centrifugal blood pumps. 
  • Heparin cofactor II-proteinase reaction products exhibit neutrophil chemoattractant activity. 
  • Heparin-associated thrombocytopenia and thrombosis: a serious clinical problem and potential solution. 
  • Hepatic capillary pressure is estimated using triple vascular occlusion method in isolated canine liver. 
  • Hepatocyte uptake of alpha 1-proteinase inhibitor-trypsin complexes in vitro: evidence for a shared uptake mechanism for proteinase complexes of alpha 1-proteinase inhibitor and antithrombin III. 
  • Heptanol but not fluoroacetate prevents the propagation of spreading depression in rat hippocampal slices. 
  • Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons. 
  • Heterogeneity of adenylate cyclase-coupled beta-adrenergic receptors. 
  • Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. 
  • High affinity binding of [3H]epibatidine to rat brain membranes. 
  • High doses of intravenous Ig inhibit in vitro uptake of C4 fragments onto sensitized erythrocytes. 
  • High expression of somatostatin receptors and messenger ribonucleic acid for its receptor subtypes in organ-confined and locally advanced human prostate cancers. 
  • High intensity focused ultrasound-induced gene activation in sublethally injured tumor cells in vitro. 
  • High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4. 
  • High-frequency S-layer protein variation in Campylobacter fetus revealed by sapA mutagenesis. 
  • High-performance liquid chromatographic method for measurement of cytochrome P450-mediated metabolism of 7-ethoxy-4-trifluoromethylcoumarin. 
  • High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina. 
  • High-threshold Ca2+ currents in rat hippocampal interneurones and their selective inhibition by activation of GABA(B) receptors. 
  • Histamine release by vancomycin: a mechanism for hypotension in man. 
  • Histamine-stimulated adenylate cyclase: blockade by imipramine and its analogues. 
  • Homologous and heterologous growth hormones fail to stimulate avian cartilage growth in vitro. 
  • Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus. 
  • Hormonal control of angiotensinogen production. 
  • How calcium causes microtubule depolymerization. 
  • Hub GABA neurons mediate gamma-frequency oscillations at ictal-like event onset in the immature hippocampus. 
  • Human IL-1 beta processing and secretion in recombinant baculovirus-infected Sf9 cells is blocked by the cowpox virus serpin crmA. 
  • Human IgE biosynthesis in vitro: studies with atopic and normal blood mononuclear cells and subpopulations. 
  • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. 
  • Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. 
  • Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control. 
  • Human complement regulatory proteins protect swine lungs from xenogeneic injury. 
  • Human lung innate immune response to Bacillus anthracis spore infection. 
  • Human melanoma cell migration along capillary-like structures in vitro: a new dynamic model for studying extravascular migratory metastasis. 
  • Human monocytes as intermediaries between allogeneic endothelial cells and allospecific T cells: a role for direct scavenger receptor-mediated endothelial membrane uptake in the initiation of alloimmunity. 
  • Human peripheral mononuclear cells do not show proinflammatory patterns of cytokine transcription in early trauma: a preliminary report. 
  • Human recombinant interleukin-1 alpha increases elastase-like enzyme in human uterine cervical fibroblasts. 
  • Human retrovirus-related synthetic peptides inhibit T lymphocyte proliferation. 
  • Human saphenous vein grafts explanted from the arterial circulation demonstrate altered smooth-muscle and endothelial responses. 
  • Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells. 
  • Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. 
  • Huntington's disease: membrane abnormalities and protein glycosylation. 
  • Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery. 
  • Hyperexcitability following moderate hypoxia in hippocampal tissue slices. 
  • Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise. 
  • Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. 
  • Hypertonic environment prevents depolarization and improves functional recovery from hypoxia in hippocampal slices. 
  • Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. 
  • Hypochlorous acid modifies calcium release channel function from skeletal muscle sarcoplasmic reticulum. 
  • Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats. 
  • Hypotonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices. 
  • Hypoxia compared with normoxia alters the effects of nitric oxide in ischemia-reperfusion lung injury. 
  • Hypoxia in the thymus: role of oxygen tension in thymocyte survival. 
  • Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung. 
  • Hypoxia-induced catecholamine secretion in isolated newborn rat adrenal chromaffin cells is mimicked by inhibition of mitochondrial respiration. 
  • Hypoxic failure of synaptic transmission in the isolated spinal cord, and the effects of divalent cations. 
  • Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. 
  • ICAM-1 (CD54) expression on B lymphocytes is associated with their costimulatory function and can be increased by coactivation with IL-1 and IL-7. 
  • IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression. 
  • Identification and antibiotic susceptibility of bacterial isolates from burned patients. 
  • Identification of Aedes aegypti and its respective life stages by real-time polymerase chain reaction. 
  • Identification of Duchenne muscular dystrophy genomic probe P20 constant Taql fragment corresponding to the EcoRV and Mspl polymorphisms. 
  • Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. 
  • Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. 
  • Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. 
  • Identification of a novel inositol bisphosphate isomer formed in chemoattractant stimulated human polymorphonuclear leukocytes. 
  • Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists. 
  • Identification of alpha-adrenergic receptors in human platelets by [3H]dihydroergocryptine binding. 
  • Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity. 
  • Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties. 
  • Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor. 
  • Identification of the cardiac beta-adrenergic receptor protein: solubilization and purification by affinity chromatography. 
  • Identification of the enzymatic mechanism of nitroglycerin bioactivation. 
  • Identification of the functionally relevant calmodulin binding site in smooth muscle caldesmon. 
  • Identification of two calcium channel receptor sites for [3H]nitrendipine in mammalian cardiac and smooth muscle membrane. 
  • Identification of two regions of beta G spectrin that bind to distinct sites in brain membranes. 
  • IgG is a prominent component of cynomolgus antiporcine natural xenoantibody. 
  • Imaging auditory representations of song and syllables in populations of sensorimotor neurons essential to vocal communication. 
  • Imaging neural activity using Thy1-GCaMP transgenic mice. 
  • Imaging of synaptically evoked intrinsic optical signals in hippocampal slices. 
  • Immune response to DNA in systemic lupus erythematosus. 
  • Immunization of normal human splenocytes in vitro to produce human monoclonal antibodies to cellular antigens. 
  • Immunoglobulin and complement receptors on human eosinophils and their role in cellular adherence to schistosomules. 
  • Immunologic control of the ascites form of murine adenocarcinoma 755. II. Tumor immunity associated with a Friend--Moloney--Ra,scher-type virus. 
  • Immunologic control of the ascites of murine adenocarcinoma 755. I. Protection with syngeneic immune serum or lymphoid cells. 
  • Immunology of infection caused by Cryptococcus neoformans. 
  • Impact of enalapril therapy on in vitro coronary artery responsiveness in pacing-induced heart failure. 
  • Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis. 
  • Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes. 
  • Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets. 
  • Impaired vasodilation by red blood cells in sickle cell disease. 
  • Improved tolerance of the pediatric myocardium to brain death. 
  • Improvement of stone fragmentation during shock-wave lithotripsy using a combined EH/PEAA shock-wave generator-in vitro experiments. 
  • In situ forces of the anterior and posterior cruciate ligaments in high knee flexion: an in vitro investigation. 
  • In the rat, chronic intermittent ethanol exposure during adolescence alters the ethanol sensitivity of tonic inhibition in adulthood. 
  • In vitro Magnetic Stimulation: A Simple Stimulation Device to Deliver Defined Low Intensity Electromagnetic Fields. 
  • In vitro analysis of stone fragmentation ability of the FREDDY laser. 
  • In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. 
  • In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models. 
  • In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts. 
  • In vitro benzo[a]pyrene diol epoxide-induced DNA adducts and risk of squamous cell carcinoma of head and neck. 
  • In vitro binding of [14C]acrylamide to neurofilament and microtubule proteins of rats. 
  • In vitro calcium and calmodulin-dependent kinase-mediated phosphorylation of rat brain and spinal cord neurofilament proteins is increased by glycidamide administration. 
  • In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors. 
  • In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings. 
  • In vitro chemotherapy testing of transitional cell carcinoma. 
  • In vitro comparative study of hemostatic components in warfarin-treated and fibrinogen-deficient plasma. 
  • In vitro comparison of standard ultrasound and pneumatic lithotrites with a new combination intracorporeal lithotripsy device. 
  • In vitro cytotoxicity of 211At-labeled trastuzumab in human breast cancer cell lines: effect of specific activity and HER2 receptor heterogeneity on survival fraction. 
  • In vitro cytotoxicity of silver nanoparticles in primary rat hepatic stellate cells. 
  • In vitro effects of lidocaine on anaerobic respiratory pathogens and strains of Hemophilus influenzae. 
  • In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome. 
  • In vitro evaluation of volumetric flow from Doppler power-weighted and amplitude-weighted mean velocities. 
  • In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use. 
  • In vitro fluid dynamics of the Ahmed glaucoma valve modified with expanded polytetrafluoroethylene. 
  • In vitro foetal wound contraction: the effect of amniotic fluid. 
  • In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides. 
  • In vitro inhibition of microsomal calcium atpase from eggshell gland of mallard duck. 
  • In vitro interleukin-6 treatment prevents mortality associated with fatty liver transplants in rats. 
  • In vitro metabolism of 10-(3-chlorophenyl)-6,8,9,10-tetrahydrobenzo[b][1,8]naphthyridin-5(7H)- one, a topical antipsoriatic agent. Use of precision-cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites. 
  • In vitro phagocytosis and intracellular fate of variously encapsulated strains of Cryptococcus neoformans. 
  • In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. 
  • In vitro properties of neurons in the rat pretectal nucleus of the optic tract. 
  • In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s). 
  • In vitro sealing of punctured fetal membranes: potential treatment for midtrimester premature rupture of membranes. 
  • In vitro secretion and uptake of radioactive vitamin A in rats fed different dietary proteins. 
  • In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax. 
  • In vitro sensitivity to ultraviolet B light and skin cancer risk: a case-control analysis. 
  • In vitro system for molybdopterin biosynthesis. 
  • In vitro temperature map of cardiac ablation demonstrates the effect of flow on lesion development. 
  • In vitro testing of a novel blood pump designed for temporary extracorporeal support. 
  • In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription. 
  • In vitro translation of RNA from the German cockroach Blattella germanica. 
  • In vitro ultrasonic imaging of flow through prosthetic heart valves. 
  • In vivo and in vitro binding of iodinated monoclonal antibody A2B5 to RIN insulinoma cells. 
  • In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by juvenile rainbow trout and common carp. 
  • In vivo and in vitro susceptibility to chloroquine of Plasmodium falciparum in Kinshasa and Mbuji-Mayi, Zaire. 
  • In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery. 
  • In vivo regulation of hTERT expression and telomerase activity by androgen. 
  • In-vitro exposure of guinea pig main bronchi to 2.5 ppm of nitrogen dioxide does not alter airway smooth muscle response. 
  • Inability of gestational hormones to account for the inhibitory effects of pregnancy plasmas on lymphocyte responses in vitro. 
  • Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse. 
  • Increased ectopic action potential generation accompanies epileptogenesis in vitro. 
  • Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures. 
  • Increased response to antigen and histamine release in smaller sensitized canine bronchi. 
  • Increased sensitivity to H2O2 in glutathione peroxidase-deficient rat granulocytes. 
  • Increased vasoconstrictor response of the mouse lacking angiotensin II type 2 receptor. 
  • Increases in ribosomal RNA within the denervated neuropil of the dentate gyrus during reinnervation: evaluation by in situ hybridization using DNA probes complementary to ribosomal RNA. 
  • Indirect and direct inhibition of dopamine beta-hydroxylase by amphetamine in storage vesicles and synaptosomes. 
  • Induced changes in orientation of the cross-bridges of glycerinated insect flight muscle. 
  • Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. 
  • Induction of ERK1/2 and histone H3 phosphorylation within the outer stripe of the outer medulla of the Eker rat by 2,3,5-tris-(glutathion-S-yl)hydroquinone. 
  • Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. 
  • Induction of TGF-beta1 in the trabecular meshwork under cyclic mechanical stress. 
  • Induction of epileptiform activity in hippocampal slices by trains of electrical stimuli. 
  • Induction of primary, antiviral cytotoxic, and proliferative responses with antigens administered via dendritic cells. 
  • Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia. 
  • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. 
  • Infection-induced thrombin production: a potential novel mechanism for preterm premature rupture of membranes (PPROM). 
  • Influence of backbone chemistry on immune activation by synthetic oligonucleotides. 
  • Influence of buffers on dV/dtmax recovery kinetics with lidocaine in myocardium. 
  • Influence of group B streptococci on piglet pulmonary artery response to bradykinin. 
  • Influence of pili, fibrils, and capsule on in vitro adherence by Haemophilus influenzae type b. 
  • Inhaled asbestos activates a complement-dependent chemoattractant for macrophages. 
  • Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules. 
  • Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis. 
  • Inhibition of EGFR signaling abrogates smooth muscle proliferation resulting from sustained distension of the urinary bladder. 
  • Inhibition of Rev activity and human immunodeficiency virus type 1 replication by antisense oligodeoxynucleotide phosphorothioate analogs directed against the Rev-responsive element. 
  • Inhibition of cell proliferation by mitomycin C incorporated into P(HEMA) hydrogels. 
  • Inhibition of human immunodeficiency virus type 1 replication and cytopathicity by synthetic soluble catecholamine melanins in vitro. 
  • Inhibition of in vitro anti-DNA B-cell responses by cyclosporine. 
  • Inhibition of major cationic inward currents prevents spreading depression-like hypoxic depolarization in rat hippocampal tissue slices. 
  • Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus. 
  • Inhibition of murine cytotoxic T lymphocyte activity by a synthetic retroviral peptide and abrogation of this activity by IL. 
  • Inhibition of muscarinic-coupled phosphoinositide hydrolysis by N-methyl-D-aspartate is dependent on depolarization via channel activation. 
  • Inhibition of poly(ADP-ribose) polymerase enhances the effect of chemotherapy in an animal model of regional therapy for the treatment of advanced extremity malignant melanoma. 
  • Inhibition of productive human immunodeficiency virus-1 infection by cobalamins. 
  • Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. 
  • Inhibition of the GABA receptor-gated chloride ion channel in brain by noncompetitive inhibitors of the nicotinic receptor-gated cation channel. 
  • Inhibition of the beta-adrenergic receptor kinase by polyanions. 
  • Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases. 
  • Inhibitor of marrow thymidine incorporation from sera of patients with uremia. 
  • Inhibitors of ATP-sensitive potassium channels stimulate intestinal cholecystokinin secretion. 
  • Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. 
  • Inhibitory proteins in the Newcastle disease virus-induced suppression of cell protein synthesis. 
  • Inhibitory role of the coronary arterial endothelium to alpha-adrenergic stimulation in experimental heart failure. 
  • Initial testing (stage 1) of the IGF-1 receptor inhibitor BMS-754807 by the pediatric preclinical testing program. 
  • Initial testing (stage 1) of the proteasome inhibitor bortezomib by the pediatric preclinical testing program. 
  • Innervation of sympathetic neurones in the guinea-pig thoracic chain. 
  • Insensible water loss from the medtronic minimax oxygenator: an In Vitro study. 
  • Instability of simple sequence DNA in Saccharomyces cerevisiae. 
  • Insulin and phorbol ester stimulate phosphorylation of acetyl-CoA carboxylase at similar sites in isolated adipocytes. Lack of correspondence with sites phosphorylated on the purified enzyme by protein kinase C. 
  • Insulin-like growth factor-1 but not growth hormone augments mammalian myocardial contractility by sensitizing the myofilament to Ca2+ through a wortmannin-sensitive pathway: studies in rat and ferret isolated muscles. 
  • Integrated catheter for 3-D intracardiac echocardiography and ultrasound ablation. 
  • Integrated endoscope for real-time 3D ultrasound imaging and hyperthermia: feasibility study. 
  • Interaction between tissue oxygen tension and NADH imaging during synaptic stimulation and hypoxia in rat hippocampal slices. 
  • Interaction of bacteria with mast cells. 
  • Interaction of bovine mitochondrial ribosomes with messenger RNA. 
  • Interaction of cefotaxime and desacetylcefotaxime against pathogenic bacteria. Assessment with the serum bactericidal test. 
  • Interaction of low density lipoproteins with human aortic elastin. 
  • Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant. 
  • Interactions between hormones and growth factors in the regulation of granulosa cell differentiation in vitro. 
  • Interactions of magnesium and verapamil on tone and contractility of vascular smooth muscle. 
  • Intercostal muscle biopsy studies in myasthenia gravis: clinical correlations and the direct effects of drugs and myasthenic serum. 
  • Interleukin 2 produced by activated B lymphocytes acts as an autocrine proliferation-inducing lymphokine. 
  • Interleukin-1 and tumor necrosis factor alpha inhibit repair of the porcine meniscus in vitro. 
  • Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma. 
  • Intermediate filament associated proteins. 
  • Interrelationship of Na, HCO3, and volatile fatty acid transport by equine large intestine. 
  • Interstitial potassium concentration, slow depolarization and focal potential responses in the dorsal horn of the rat spinal slice. 
  • Interstitial space, electrical resistance and ion concentrations during hypotonia of rat hippocampal slices. 
  • Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. 
  • Intracardiac echocardiography and acoustic radiation force impulse imaging of a dynamic ex vivo ovine heart model. 
  • Intracellular recording from dopamine neurons in the substantia nigra: double labelling for identification of projection site and morphological features. 
  • Intravenous immunoglobulin therapy induces neutrophil apoptosis in Kawasaki disease. 
  • Intrinsic optical signals in rat hippocampal slices during hypoxia-induced spreading depression-like depolarization. 
  • Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. 
  • Investigation of reduced nicotinamide adenine dinucleotide phosphate and acyl-binding sites on avian fatty acid synthase. 
  • Investigation of the complexes of EcoRI endonuclease with decanucleotides containing canonical and modified recognition sequences using fluorescence and optical detection of magnetic resonance spectroscopy. 
  • Investigation of the role of prostaglandins in nitroglycerin-induced relaxation of isolated rabbit blood vessels. 
  • Investigations into the role of sulfhydryl groups in the mechanism of action of the nitrates. 
  • Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. 
  • Involvement of cAMP-dependent protein kinase in mu-opioid modulation of NMDA-mediated synaptic currents. 
  • Involvement of radical species in the oxidation of aminopyrine and 4-aminoantipyrine by cumene hydroperoxide in rat liver microsomes. 
  • Involvement of the beta clamp in methyl-directed mismatch repair in vitro. 
  • In vitro and in vivo evaluation of resveratrol and 3,5-dihydroxy-4'-acetoxy-trans-stilbene in the treatment of human prostate carcinoma and melanoma. 
  • Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine. 
  • Ion channel involvement in hypoxia-induced spreading depression in hippocampal slices. 
  • Ionic and nucleotide cofactor requirements for uptake of [3H]norepinephrine by rat brain synaptic vesicle preparations. 
  • Ionic basis of phenytoin sodium inhibition of insulin secretion in pancreatic islets. 
  • Is myosin a "back door" enzyme? 
  • Isoflurane, but not halothane, induces protection of human myocardium via adenosine A1 receptors and adenosine triphosphate-sensitive potassium channels. 
  • Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. 
  • Isolated perfused lung--substrate utilization. 
  • Isolation and analysis of cDNA clones expressing human lupus La antigen. 
  • Isolation of embryonic chick motoneurons and their survival in vitro. 
  • Isolation of lysophosphatidylethanolamine from human serum. 
  • Isotonic smooth muscle response in human bronchi exposed in vitro to nitrogen dioxide. 
  • K channel subconductance levels result from heteromeric pore conformations. 
  • Kainic acid inhibits cholecystokinin release from rat hippocampal slices. 
  • Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA. 
  • Kinematics of hamster sperm during penetration of the cumulus cell matrix. 
  • Kinematics of the knee at high flexion angles: an in vitro investigation. 
  • Kinetic isolation of a slowly recovering component of short-term depression during exhaustive use at excitatory hippocampal synapses. 
  • Kinetic measurements of the release of prostaglandins from perfused rat lungs. 
  • Kinetics of interaction of the lidocaine metabolite glycylxylidide with the cardiac sodium channel. Additive blockade with lidocaine. 
  • Knee-loading modality drives molecular transport in mouse femur. 
  • L-glucosylceramide: synthesis, properties, and resistance to catabolism by glucocerebrosidase in vitro. 
  • La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. 
  • Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography. 
  • Lack of effect of ammonium glycyrrhizinate on the morphology of ovine nasal mucosa in vitro. 
  • Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice. 
  • Lambert-Eaton myasthenic syndrome: the lack of short-term in vitro effects of serum factors on neuromuscular transmission. 
  • Laminin oligopeptide derivatized agarose gels allow three-dimensional neurite extension in vitro. 
  • Lasting neuron depression induced by high potassium and its prevention by low calcium and NMDA receptor blockade. 
  • Lateral diffusion in planar lipid bilayers. 
  • Leishmaniasis in the Sudan Republic. 25. Experimental visceral leishmaniasis in the Nile grass rat, Arvicanthis niloticus niloticus Dollman. 
  • Lesions of an avian forebrain nucleus that disrupt song development alter synaptic connectivity and transmission in the vocal premotor pathway. 
  • Leucine periodicity of U2 small nuclear ribonucleoprotein particle (snRNP) A' protein is implicated in snRNP assembly via protein-protein interactions. 
  • Leukotrienes in renal transplant rejection in rats. Distinct roles for leukotriene B4 and peptidoleukotrienes in the pathogenesis of allograft injury. 
  • Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells. 
  • Limit on the role of activity in controlling the release-ready supply of synaptic vesicles. 
  • Linking ligand-induced alterations in androgen receptor structure to differential gene expression: a first step in the rational design of selective androgen receptor modulators. 
  • Lipopolysaccharide upregulates bradykinin 1 receptors in the isolated mouse bladder. 
  • Liposomal delivery of soluble protein antigens for class I MHC-mediated antigen presentation. 
  • Local calcium release in dendritic spines required for long-term synaptic depression. 
  • Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. 
  • Local excitatory circuits in the intermediate gray layer of the superior colliculus. 
  • Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex. 
  • Localization of sites through which C-reactive protein binds and activates complement to residues 14-26 and 76-92 of the human C1q A chain. 
  • Localization of specific binding sites for bombesin in the canine gastrointestinal tract. 
  • Long- and short-range interactions between phospholipid/ganglioside GM1 bilayers. 
  • Long-range inhibition within the zebra finch song nucleus RA can coordinate the firing of multiple projection neurons. 
  • Long-term potentiation induced by theta frequency stimulation is regulated by a protein phosphatase-1-operated gate. 
  • Loss of atm radiosensitizes multiple p53 null tissues. 
  • Loss of autoreceptor functions in mice lacking the dopamine transporter. 
  • Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. 
  • Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum. 
  • Low dose heparin therapy: in vitro verification of antithrombotic effect. 
  • Low interleukin-12 activity in severe Plasmodium falciparum malaria. 
  • Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. 
  • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. 
  • Lymphokine-activated killer cell activity after cryopreservation. 
  • Lysosomal enzyme release from luteinized rat ovaries by prostaglandin f2alpha. 
  • Lysosomal fragility induced by prostaglandin F 2 . 
  • MR imaging of experimental and clinical thrombi at 1.5 T. 
  • Magnesium-dependent inhibition of N-methyl-D-aspartate receptor-mediated synaptic transmission by ethanol. 
  • Magnesium-free medium activates seizure-like events in the rat hippocampal slice. 
  • Magnetic resonance imaging of blood flow with a phase subtraction technique. In vitro and in vivo validation. 
  • Magnitude and ethanol sensitivity of tonic GABAA receptor-mediated inhibition in dentate gyrus changes from adolescence to adulthood. 
  • Mammary implants, diving, and altitude exposure. 
  • Manganese porphyrins and related compounds as mimics of superoxide dismutase. 
  • Material characterization of in vivo and in vitro porcine brain using shear wave elasticity. 
  • Maturation of acetylcholinesterase expression in tracheal smooth muscle contraction. 
  • Maturation of neuromodulatory effect of substance P in rabbit airways. 
  • Maturation of sympathetic neurotransmission in the rat heart--III. Developmental changes in reserpine inhibition of norepinephrine uptake into isolated synaptic vesicles. 
  • Maturation of sympathetic neurotransmission in the rat heart. VII. Suppression of sympathetic responses by dexamethasone. 
  • Maturation of the adrenal medulla--IV. Effects of morphine. 
  • Maturation of the adrenal medulla. I. Uptake and storage of amines in isolated storage vesicles of the rat. 
  • Maturation of the adrenal medulla. II. Content and properties of catecholamine storage vesicles of the rat. 
  • Maximization of contrast-to-noise ratio to distinguish diffusion and microcirculatory flow. 
  • Maximizing the retention of antigen specific lymphocyte function after cryopreservation. 
  • MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. 
  • Measurement of 25-hydroxyvitamin D-1 alpha-hydroxylase activity in mammalian kidney. 
  • Measurement of endothelial permeability to 125I-low density lipoproteins in rabbit arteries by use of en face preparations. 
  • Measurement of in vivo corrosion rates in baboons, and correlation with in vitro tests. 
  • Measurement of left ventricular volume in normal and volume-overloaded canine hearts. 
  • Mechanical determinants of myocardial oxygen consumption in conscious dogs. 
  • Mechanical properties of a dental ceramic coated by RF magnetron sputtering. 
  • Mechanical property studies of human gallstones. 
  • Mechanically stimulated cytoskeleton rearrangement and cortical contraction in human neutrophils. 
  • Mechanics of sperm-egg interaction at the zona pellucida. 
  • Mechanism and specificity of lanthanide series cation transport by ionophores A23187, 4-BrA23187, and ionomycin. 
  • Mechanism of adenosine accumulation in the hippocampal slice during energy deprivation. 
  • Mechanism of electrographic seizure generation in the hippocampal slice in Mg2+-free medium: the role of GABAa inhibition. 
  • Mechanism of estrogen action: early transcriptional and translational events. 
  • Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. 
  • Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter. 
  • Mechanisms of corticosteroid action on lymphocyte subpopulations. IV. Effects of in vitro hydrocortisone on naturally occuring and mitogen-induced suppressor cells in man. 
  • Mechanisms of epileptogenesis. 
  • Mechanisms of increased hippocampal excitability in the Mashl+/- mouse model of Na+ /K+ -ATPase dysfunction. 
  • Mechanisms of membrane-receptor regulation. Biochemical, physiological, and clinical insights derived from studies of the adrenergic receptors. 
  • Mechanisms of nonimmunological histamine and tryptase release from human cutaneous mast cells. 
  • Membrane currents in CA1 pyramidal cells during spreading depression (SD) and SD-like hypoxic depolarization. 
  • Membrane fusion promoters and inhibitors have contrasting effects on lipid bilayer structure and undulations. 
  • Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14. 
  • Membrane tethers formed from blood cells with available area and determination of their adhesion energy. 
  • Merosin promotes neurite growth and Schwann cell migration in vitro and nerve regeneration in vivo: evidence using an antibody to merosin, ARM-1. 
  • Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha. 
  • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. 
  • Meta-[211At]astatobenzylguanidine: further evaluation of a potential therapeutic agent. 
  • Meta-iodobenzylguanidine derivatives containing a second guanidine moiety. 
  • Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study. 
  • Metabolism of N-alkyl compounds during the biosynthesis of prostaglandins. N-Dealkylation during prostaglandin biosynthesis. 
  • Metabolism of amphetamine by rat brain tissue. 
  • Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo. 
  • Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. 
  • Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE. 
  • Microelectrode study of the genesis of the monophasic action potential by contact electrode technique. 
  • Microglia and memory: modulation by early-life infection. 
  • Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission. 
  • Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study. 
  • Mitochondrial NADH as the bellwether of tissue O2 delivery. 
  • Mitochondrial and intrinsic optical signals imaged during hypoxia and spreading depression in rat hippocampal slices. 
  • Model of tumor dormancy/recurrence after short-term chemotherapy. 
  • Modeling geriatric depression in animals: biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats. 
  • Modeling the effects of electric fields on nerve fibers: determination of excitation thresholds. 
  • Modification of integrin-mediated cell attachment to substrata by serine proteinases in the presence and absence of divalent cations. 
  • Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes. 
  • Modulation of glutamate and aspartate release from slices of hippocampal area CA1 by inhibitors of arachidonic acid metabolism. 
  • Modulation of mouse peritoneal macrophage Ia and human peritoneal macrophage HLA-DR expression by alpha 2-macroglobulin "fast" forms. 
  • Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain. 
  • Modulation of natural IgM binding and complement activation by natural IgG antibodies: a role for IgG anti-Gal alpha1-3Gal antibodies. 
  • Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins. 
  • Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. 
  • Modulation of vasoactive intestinal peptide pulmonary relaxation by NO in tracheally superfused guinea pig lungs. 
  • Molecular interactions of B-CAM (basal-cell adhesion molecule) and laminin in epithelial skin cancer. 
  • Molecular mechanisms of activation and desensitization of adenylate cyclase coupled beta-adrenergic receptors. 
  • Molecular mechanisms of beta-adrenergic receptor desensitization. 
  • Molecular pharmacology of alpha adrenergic receptors: utilization of [3H]dihydroergocryptine binding in the study of pharmacological receptor alterations. 
  • Molecular signals in B cell activation. I. Differential refractory effects of incomplete signaling by ionomycin or PMA relate to autocrine IL-2 production and IL-2R expression. 
  • Molecular signals in B cell activation. II. IL-2-mediated signals are required in late G1 for transition to S phase after ionomycin and PMA treatment. 
  • Monitoring cellular immune responses to cancer immunotherapy. 
  • Monoamine oxidase of rat skeletal muscle: substrate specificity and half-life. 
  • Monoclonal antibody OKT3-induced T cell proliferation: differential role of HLA class II determinants expressed by T cells and monocytes. 
  • Monocyte chemotactic mechanisms in patients with hypernephroma. 
  • Monokines released during short-term Fc gamma receptor phagocytosis up-regulate polymorphonuclear leukocytes and monocyte-phagocytic function. 
  • Morphine produces a multiphasic effect on the release of substance P from rat trigeminal nucleus slices by activating different opioid receptor subtypes. 
  • Mossy fiber lesion reduces the probability that kainic acid will provoke CA3 hippocampal pyramidal cell bursting. 
  • Mossy fiber-granule cell synapses in the normal and epileptic rat dentate gyrus studied with minimal laser photostimulation. 
  • Movement characteristics of hamster and guinea pig spermatozoa upon attachment to the zona pellucida. 
  • Movement of bull spermatozoa in cervical mucus. 
  • Mu opioid receptor-mediated modulation of synaptic currents in dentate granule cells of rat hippocampus. 
  • Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices. 
  • Multiple mass isotopomer tracing of acetyl-CoA metabolism in Langendorff-perfused rat hearts: channeling of acetyl-CoA from pyruvate dehydrogenase to carnitine acetyltransferase. 
  • Multiple power-density windows and their possible origin. 
  • Multiple reactive sulfhydryl groups modulate the function of adenylate cyclase coupled beta-adrenergic receptors. 
  • Multivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors. 
  • Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. 
  • Myocardial beta-adrenergic receptors from adrenalectomized rats: impaired formation of high-affinity agonist-receptor complexes. 
  • Myogenic constriction of human coronary arterioles. 
  • N-acetylcysteine does not modify nitroglycerin-induced tolerance in canine vascular rings. 
  • N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor. 
  • N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis. 
  • N-o-Methoxyphenylpiperazine: a simple blocker of dopaminergic receptors in the brain. 
  • N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase. 
  • NAD+ modulates p53 DNA binding specificity and function. 
  • NIDA522131, a new radioligand for imaging extrathalamic nicotinic acetylcholine receptors: in vitro and in vivo evaluation. 
  • NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model. 
  • NMDA receptor antagonists disinhibit rat posterior cingulate and retrosplenial cortices: a potential mechanism of neurotoxicity. 
  • NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells. 
  • Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus. 
  • Ncm-D-aspartate: a novel caged D-aspartate suitable for activation of glutamate transporters and N-methyl-D-aspartate (NMDA) receptors in brain tissue. 
  • Near infrared spectroscopy: in situ studies of skeletal and cardiac muscle. 
  • Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. 
  • Neocortical disynaptic inhibition requires somatodendritic integration in interneurons. 
  • Neonatal rat pinealocytes: typical and atypical characteristics of [125I]iodohydroxybenzylpindolol binding and adenosine 3',5'-monophosphate accumulation. 
  • Nerve growth factor and its low-affinity receptor promote Schwann cell migration. 
  • Neuregulin-1 enhances depolarization-induced GABA release. 
  • Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: cellular mechanisms and the reversal of deficits by neural grafts. 
  • Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate. 
  • Neurokinin receptors mediating substance P-induced contraction in adult rabbit airways. 
  • Neuromodulation mediated by neurokinin-1 subtype receptors in adult rabbit airways. 
  • Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys. 
  • Neuronal localization of the enhanced adenylate cyclase responsiveness to catecholamines in the rat cerebral cortex following reserpine injections. 
  • Neuronal transfection in brain slices using particle-mediated gene transfer. 
  • Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors. 
  • Neurotensin reduces glutamatergic transmission in the dorsolateral striatum via retrograde endocannabinoid signaling. 
  • Neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate. 
  • Neurotrophin regulation of cortical dendritic growth requires activity. 
  • Newly identified brain potassium channels gated by the guanine nucleotide binding protein Go. 
  • Next-Generation Single-Use Ureteroscopes: An In Vitro Comparison. 
  • Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia. 
  • Nicotinic cholinergic receptors labeled by [3H]acetylcholine in rat brain. 
  • Nitric oxide and differential effects of ATP on mitochondrial permeability transition. 
  • Nitric oxide as a mediator of relaxation of the corpus cavernosum. 
  • Nitric oxide is a potent relaxant of human and rabbit corpus cavernosum. 
  • Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. 
  • Nitric oxide synthase is an active enzyme in the spiral ganglion cells of the rat cochlea. 
  • Nitrofurantoin-stimulated superoxide production by channel catfish (Ictalurus punctatus) hepatic microsomal and soluble fractions. 
  • No-carrier-added synthesis of meta-[131I]iodobenzylguanidine. 
  • Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. 
  • Non-anatomical capsular closure of a standard parapatellar knee arthrotomy leads to patellar maltracking and decreased range of motion: a cadaver study. 
  • Non-invasive vesicoureteral reflux detection: heating risk studies for a new device. 
  • Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats. 
  • Nonpeptidic Amphiphilic Xanthone Derivatives: Structure-Activity Relationship and Membrane-Targeting Properties. 
  • Norepinephrine: dissociation of -receptor binding from adenylate cyclase activation in solubilized myocardium. 
  • Normal endothelial function and decreased vasoreactivity of experimental arterial grafts. 
  • Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. 
  • Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. 
  • Novel tricyclic inhibitors of IkappaB kinase. 
  • Novel vascular effects of isoprenaline following pacing-induced heart failure in the dog. 
  • Nucleic acid aptamers in therapeutic anticoagulation. Technology, development and clinical application. 
  • Observations of tissue response to acoustic radiation force: opportunities for imaging. 
  • Observations on man in an oxygen-helium environment at 380 mm. Hg total pressure. I. Clinical. 
  • Observations on man in an oxygen-helium environment at 380 mm. Hg total pressure. II. Respiratory. 
  • Obstruction of aqueous outflow by lens particles and by heavy-molecular-weight soluble lens proteins. 
  • Occurrence of lacto series gangliosides 3'-isoLM1 and 3',6'-isoLD1 in human gliomas in vitro and in vivo. 
  • Okadaic acid disrupts synaptic vesicle trafficking in a ribbon-type synapse. 
  • On the purpose of selective innervation of guinea-pig superior cervical ganglion cells. 
  • Ongoing electrical activity of superior cervical ganglion cells in mammals of different size. 
  • Ontogenesis of myosin light chain phosphorylation in guinea pig tracheal smooth muscle. 
  • Ontogeny of (--)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain. 
  • Ontogeny of histaminergic neurotransmission in the rat brain: concomitant development of neuronal histamine, H-1 receptors, and H-1 receptor-mediated stimulation of phospholipid turnover. 
  • Ontogeny of shortening velocity in porcine trachealis. 
  • Ontogeny of the eotaxins in human lung. 
  • Ontogeny of the smooth muscle response to histamine in rabbit and human small bowel. 
  • Open Na+ channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine. 
  • Opioid-induced epileptiform bursting in hippocampal slices: higher susceptibility in ventral than dorsal hippocampus. 
  • Optical imaging of hippocampal neurons with a chloride-sensitive dye: early effects of in vitro ischemia. 
  • Optical imaging of living brain slices. 
  • Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress. 
  • Optical measurements of transmembrane potential changes during electric field stimulation of ventricular cells. 
  • Optical rotatory dispersion of ribonuclease and ribonuclease--nucleotide complexes. 
  • Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents. 
  • Optimized image acquisition for breast tomosynthesis in projection and reconstruction space. 
  • Organization of the intermediate gray layer of the superior colliculus. I. Intrinsic vertical connections. 
  • Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. 
  • Ouabain effects on intracellular potassium activity and contractile force in cat papillary muscle. 
  • Overexpression of alpha 2-adrenergic receptors in fetal rat heart: receptors in search of a function. 
  • Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion. 
  • Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. 
  • Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. 
  • Overshoot of oxygen pressure in post-hypoxic brain tissue: a re-evaluation. 
  • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen. 
  • Oxidative stress increases hepatocyte iNOS gene transcription and promoter activity. 
  • OxyR: a molecular code for redox-related signaling. 
  • Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease. 
  • Ozone primes alveolar macrophage-derived innate immunity in healthy human subjects. 
  • P-selectin induces the expression of tissue factor on monocytes. 
  • PDGF-stimulated fibroblast proliferation is enhanced synergistically by receptor-recognized alpha 2-macroglobulin. 
  • PLCgamma signaling underlies BDNF potentiation of Purkinje cell responses to GABA. 
  • PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation. 
  • PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. 
  • PRImary care Streptococcal Management (PRISM) study: in vitro study, diagnostic cohorts and a pragmatic adaptive randomised controlled trial with nested qualitative study and cost-effectiveness study. 
  • PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. 
  • Paradoxical effects of methylmercury on the kinetics of cytochrome c oxidase. 
  • Partial purification of a prorenin activating enzyme in the aortic wall. 
  • Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. 
  • Passive mechanical properties of uterine muscle (myometrium) tested in vitro. 
  • Pathogenesis of autoimmunity in pemphigus. 
  • Pathophysiology of the spinal cord studied in vitro. 
  • Penicillin effects on iontophoretic responses in Aplysia californica. 
  • Penicillin resistance is not extrapolable to amoxicillin resistance in Streptococcus pneumoniae isolated from middle ear fluid in children with acute otitis media. 
  • Peptide and amine modulation of the Limulus heart: a simple neural network and its target tissue. 
  • Periodic, partial inhibition of IkappaB Kinase beta-mediated signaling yields therapeutic benefit in preclinical models of rheumatoid arthritis. 
  • Peripheral atherectomy: experimental results with a new device. 
  • Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord. 
  • Permeability criteria for effective function of passive countercurrent multiplier. 
  • Phaclofen antagonizes post-tetanic disinhibition in the rat dentate gyrus. 
  • Phagocytosis and killing of Cryptococcus neoformans by rat alveolar macrophages in the absence of serum. 
  • Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine. 
  • Pharmacological activity of nitroxide analogues of dichloroisoproterenol and propranolol. 
  • Pharmacological effects of 2-aminotetralins, octahydrobenzo[f]quinolines and clonidine on the isolated guinea pig ileum. 
  • Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder. 
  • Pharmacologically distinct presynaptic calcium channels in cerebellar excitatory and inhibitory synapses. 
  • Phase I and pharmacokinetic study of gimatecan given orally once a week for 3 of 4 weeks in patients with advanced solid tumors. 
  • Phasic ion channel blockade. A kinetic model and parameter estimation procedure. 
  • Phorbol esters down-regulate protein kinase C in rat brain cerebral cortical slices. 
  • Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity. 
  • Phospholipids in the androgen stimulated sexual segment of the kidney of the Indian house lizard, Hemidactylus flaviviridis Rüppell. 
  • Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. 
  • Phosphorylation of caldesmon by mitogen-activated protein kinase with no effect on Ca2+ sensitivity in rabbit smooth muscle. 
  • Phosphorylation of non-bleached rhodopsin in intact retinas and living frogs. 
  • Phosphorylation-dependent power output of transgenic flies: an integrated study. 
  • Phosphotyrosine and phosphoprotein phosphatase activity of alkaline phosphatase in mineralizing cartilage. 
  • Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta. 
  • Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120. 
  • Physiological effects and metabolism of gossypol. 
  • Physiological mechanisms mediating enhanced force generation during development and immune sensitization. 
  • Physiology of neuronal subtypes in the respiratory-vocal integration nucleus retroamigualis of the male zebra finch. 
  • Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR. 
  • Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal. 
  • Pigment production from tryptophan by an Achromobacter species. 
  • Pigtail catheters used for percutaneous fluid drainage: comparison of performance characteristics. 
  • Plaque modification with tetracycline: enhanced tissue ablation with the excimer laser. 
  • Platelet heterogeneity: variation in coagulation complexes on platelet subpopulations. 
  • Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors. 
  • Platelet uptake of the pheochromocytoma-scanning agent 131I-meta-iodobenzylguanadine. 
  • Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. 
  • Pollutant particles produce vasoconstriction and enhance MAPK signaling via angiotensin type I receptor. 
  • Polynitrosylated proteins: characterization, bioactivity, and functional consequences. 
  • Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. 
  • Post-ictal depression transiently inhibits induction of LTP in area CA1 of the rat hippocampal slice. 
  • Post-natal reduction of neural unit size in the rabbit ciliary ganglion. 
  • Postischemic synaptic physiology in area CA1 of the gerbil hippocampus studied in vitro. 
  • Postnatal Erythropoietin Mitigates Impaired Cerebral Cortical Development Following Subplate Loss from Prenatal Hypoxia-Ischemia. 
  • Postsynaptic mechanisms govern the differential excitation of cortical neurons by thalamic inputs. 
  • Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. 
  • Potassium-induced epileptiform activity in area CA3 varies markedly along the septotemporal axis of the rat hippocampus. 
  • Potential role for a guanine nucleotide regulatory protein in chemoattractant receptor mediated polyphosphoinositide metabolism, Ca++ mobilization and cellular responses by leukocytes. 
  • Precipitation of fibrinogen, fibrinogen degradation products and fibrin monomer by histone H3. 
  • Preexposure of resting B cells to interferon-gamma enhances their proliferative response to subsequent activation signals. 
  • Preferential uncoupling by manganese of alpha adrenergic receptor mediated inhibition of adenylate cyclase in human platelets. 
  • Prenatal choline exposure alters hippocampal responsiveness to cholinergic stimulation in adulthood. 
  • Prenatal dietary choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats. 
  • Preparation and study of human eyes obtained postmortem with the Miyake posterior photographic technique. 
  • Presynaptic BK channels modulate ethanol-induced enhancement of GABAergic transmission in the rat central amygdala nucleus. 
  • Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse. 
  • Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. 
  • Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine. 
  • Primary tumor genotype is an important determinant in identification of lung cancer propagating cells. 
  • Priming of platelet alphaIIbbeta3 by oxidants is associated with tyrosine phosphorylation of beta3. 
  • Proceedings: Hormonal control of steroid synthesis by a feminizing adrenal tumour. 
  • Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro. 
  • Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration. 
  • Production of superoxide anion by an NADPH-oxidase from rat pulmonary macrophages. 
  • Prognostic significance of early response to a single dose of asparaginase in childhood acute lymphoblastic leukemia. 
  • Progressive loss of synaptic integrity in human apolipoprotein E4 targeted replacement mice and attenuation by apolipoprotein E2. 
  • Proline-induced inhibition of glutamate release in hippocampal area CA1. 
  • Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution. 
  • Prolonged exposure to high potassium concentration results in irreversible loss of synaptic transmission in hippocampal tissue slices. 
  • Prolonged inhibition in burst firing neurons: synaptic inactivation of the slow regenerative inward current. 
  • Propagation of spreading depression among dendrites and somata of the same cell population. 
  • Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex. 
  • Prostaglandins and renin release: III. Effects of PGE1, E2 F2 alpha and D2 on renin release from rabbit renal cortical slices. 
  • Prostaglandins modulate hormonal effects on rabbit myometrial alpha 1-adrenergic responses. 
  • Prosthetic silicone scaphoid strains: effects of intercarpal fusions. 
  • Protamine reversal of heparin affects platelet aggregation and activated clotting time after cardiopulmonary bypass. 
  • Protection against platelet-activating factor-induced injury by interferon inducer in perfused rabbit lung. 
  • Protection of perfused lung from oxidant injury by inhibitors of anion exchange. 
  • Protective effect of cardioplegia with poly (ADP-ribose) polymerase-1 inhibitor against myocardial ischemia-reperfusion injury: in vitro study of isolated rat heart model. 
  • Protein biosynthesis in the testis. 3. Dual effect of glucose. 
  • Protein biosynthesis in the testis. I. Comparison between stimulation by FSH and glucose. 
  • Protein biosynthesis in the testis. II. Role of adenosine triphosphate (ATP) in stimulation by glucose. 
  • Protein biosynthesis in the testis. V. Concerning the mechanism of stimulation by follicle-stimulating hormone. 
  • Protein kinase C-zeta is critical in pancreatitis-induced apoptosis of Kupffer cells. 
  • Protein patterns of early mouse embryos during development. 
  • Protein synthesis inhibition blocks maintenance but not induction of epileptogenesis in hippocampal slice. 
  • Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. 
  • Psychological determinants of problematic outcomes following Total Knee Arthroplasty. 
  • Pullout strength of suture anchors: effect of mechanical properties of trabecular bone. 
  • Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione. 
  • Pump-probe imaging differentiates melanoma from melanocytic nevi. 
  • Purification and characterization of the mammalian myosin light chain phosphatase holoenzyme. The differential effects of the holoenzyme and its subunits on smooth muscle. 
  • Purification and reconstitution of the ryanodine- and caffeine-sensitive Ca2+ release channel complex from muscle sarcoplasmic reticulum. 
  • Purification of replication protein C, a cellular protein involved in the initial stages of simian virus 40 DNA replication in vitro. 
  • Purification, characterization, and structural elucidation of the active moiety of the previously called "suppressor activating factor (SAF)". 
  • Pursuit of the mechanisms of kindling. 
  • Putrescine content and structural defects in isolated fractions of rat brain after reversible cerebral ischemia. 
  • QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immunization in humans. 
  • Quantification of gas denucleation and thrombogenicity of vascular grafts. 
  • Quantification of in vitro endothelial cell adhesion to vascular graft material. 
  • Quantitation of in vivo measurements with carbon fiber microelectrodes. 
  • Quantitative autoradiography of nicotinic [3H]acetylcholine binding sites in rat brain. 
  • Quantitative evaluation of acute renal transplant dysfunction with low-dose three-dimensional MR renography. 
  • Quantitative proton spectroscopy of canine brain: in vivo and in vitro correlations. 
  • Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique. 
  • R-(-)-beta-phenyl-GABA is a full agonist at GABAB receptors in brain slices but a partial agonist in the ileum. 
  • RGS expression rate-limits recovery of rod photoresponses. 
  • Radiohistochemical demonstration of NMDA/glycine-channel activation in rat hippocampus. 
  • Radon dosimetry based on the depth distribution of nuclei in human and rat lungs. 
  • Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor. 
  • Rapacuronium preferentially antagonizes the function of M2 versus M3 muscarinic receptors in guinea pig airway smooth muscle. 
  • Rapid deformation of "passive" polymorphonuclear leukocytes: the effects of pentoxifylline. 
  • Rapid disappearance of nitroglycerin following incubation with human blood. 
  • Rapid flow of passive neutrophils into a 4 microns pipet and measurement of cytoplasmic viscosity. 
  • Rapid in vitro assembly dynamics and subunit turnover of FtsZ demonstrated by fluorescence resonance energy transfer. 
  • Rapid measurements of diastolic intramyocardial vascular volume. 
  • Rapid tracking of small displacements with ultrasound. 
  • Rat placental lactogen-I binds to the choroid plexus and hypothalamus of the pregnant rat. 
  • Reaction of a cobra venom factor with guinea pig complement and generation of an activity chemotactic for polymorphonuclear leukocytes. 
  • Reactions between nitric oxide and haemoglobin under physiological conditions. 
  • Reactivation of latent murine cytomegalovirus from kidney. 
  • Real-time analysis of sperm motion using automatic video image digitization. 
  • Real-time in vivo proteomic identification of novel kinase substrates in smooth muscle. 
  • Real-time three-dimensional intracardiac echocardiography. 
  • Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity. 
  • Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages. 
  • Recognition and cleavage of primary microRNA transcripts. 
  • Recognition and processing of randomly fluctuating electric signals by Na,K-ATPase. 
  • Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. 
  • Reconstitution of simian virus 40 DNA replication with purified proteins. 
  • Recording evoked potentials during deep brain stimulation: development and validation of instrumentation to suppress the stimulus artefact. 
  • Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction. 
  • Reduced reperfusion-induced Ins(1,4,5)P3 generation and arrhythmias in hearts expressing constitutively active alpha1B-adrenergic receptors. 
  • Reduced sensitivity of the N-methyl-D-aspartate component of synaptic transmission to magnesium in hippocampal slices from immature rats. 
  • Reducing agents inhibit the contractile response of isolated guinea-pig main bronchi. 
  • Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. 
  • Reduction of voltage-dependent currents by ethanol contributes to inhibition of NMDA receptor-mediated excitatory synaptic transmission. 
  • Regenerative, all-or-none electrographic seizures in the rat hippocampal slice in Mg-free and physiological medium. 
  • Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression. 
  • Regional structure-function relationships in mouse aortic valve tissue. 
  • Regionally distinct stoichiometry for N-methyl-D-aspartate receptor domains in brain. 
  • Regions of the 110-kDa regulatory subunit M110 required for regulation of myosin-light-chain-phosphatase activity in smooth muscle. 
  • Regression of atherosclerosis in monkeys reduces vascular superoxide levels. 
  • Regulated expression of p18, a major phosphoprotein of leukemic cells. 
  • Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex. 
  • Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage. 
  • Regulation of beta adrenergic receptors in isolated frog erythrocyte plasma membranes. 
  • Regulation of cholecystokinin secretion by calcium-dependent calmodulin kinase II: differential effects of phenylalanine and cAMP. 
  • Regulation of factor Xa in vitro in human and mouse plasma and in vivo in mouse. Role of the endothelium and plasma proteinase inhibitors. 
  • Regulation of glutamate and aspartate release from the Schaffer collaterals and other projections of CA3 hippocampal pyramidal cells. 
  • Regulation of insulin receptors in frog erythrocytes by insulin and concanavalin A. Evidence for discrete classes of insulin binding sites. 
  • Regulation of islet beta-cell pyruvate metabolism: interactions of prolactin, glucose, and dexamethasone. 
  • Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses. 
  • Regulation of plasminogen activation by components of the extracellular matrix. 
  • Regulation of protein kinase C in NG108-15 cell differentiation. 
  • Regulation of rat heart ornithine decarboxylase: change in affinity for ornithine evoked by neuronal, hormonal, and ontogenetic stimuli. 
  • Regulation of the amino-terminal transcription activation domain of progesterone receptor by a cofactor-induced protein folding mechanism. 
  • Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current. 
  • Relationship between ischemic contracture and mitochondrial function. 
  • Relationship of Inb antigen to other antigens on In(Lu)-related p80. 
  • Relationship of in vitro morphologic and growth characteristics of established human glioma-derived cell lines to their tumorigenicity in athymic nude mice. 
  • Relationships between in vivo and in vitro measurements of metabolism in young and old human calf muscles. 
  • Relationships of mammalian sperm motility and morphology to hydrodynamic aspects of cell function. 
  • Relative contributions of rod and cone bipolar cell inputs to AII amacrine cell light responses in the mouse retina. 
  • Relaxation of guinea pig trachealis during electrical field stimulation increases with age. 
  • Release of [3H]norepinephrine from synaptic vesicles isolated from rat brain after the intracisternal administration of [3H]norepinephrine: influence of nucleotides, ions and drugs, and destabilization of transmitter storage caused by acute or chronic lithium administration. 
  • Release of corticotropin-releasing factor from rat brain regions in vitro. 
  • Release of cytochrome c from liver mitochondria during permeability transition. 
  • Relevance of classification by size to topographical differences in bronchial smooth muscle response. 
  • Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors. 
  • Renal segmental microvascular responses to ANG II in AT1A receptor null mice. 
  • Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood-brain barrier model. 
  • Rescue of neurological deficits in a mouse model for Angelman syndrome by reduction of alphaCaMKII inhibitory phosphorylation. 
  • Reserpine-like effects of harmine on isolated adrenal medullary vesicles. 
  • Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. 
  • Respiratory and telencephalic modulation of vocal motor neurons in the zebra finch. 
  • Response of blood leukocytes to thrombin receptor peptides. 
  • Responsiveness of vein bypass grafts to stimulation with norepinephrine and 5-hydroxytryptamine. 
  • Retina: pathology of neodymium and ruby laser burns. 
  • Retinal oxygen consumption in vitro. The effect of diabetes mellitus, oxygen and glucose. 
  • Retinal representation of the elementary visual signal. 
  • Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus. 
  • Reversible effects of hypoxia on neurons in mouse dorsal root ganglia in vitro. 
  • Risk of heparin-induced thrombocytopenia from heparin-bonded vascular prostheses. 
  • Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. 
  • Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. 
  • Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. 
  • Role of TGF-beta1 in renal parenchymal scarring following childhood urinary tract infection. 
  • Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors. 
  • Role of calcium channels in spreading depression in rat hippocampal slices. 
  • Role of circulating blood components and thromboxane in anaphylactic vasoconstriction in isolated canine lungs. 
  • Role of competition for nutrients in suppression of Clostridium difficile by the colonic microflora. 
  • Role of glutathione in cellular resistance to alkylating agents. 
  • Role of intrinsic synaptic circuitry in collicular sensorimotor integration. 
  • Role of nitric oxide in human esophageal circular smooth muscle in vitro. 
  • Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin. 
  • Role of sphingosine kinase activity in protection of heart against ischemia reperfusion injury. 
  • Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampus. 
  • Role of the membrane cortex in neutrophil deformation in small pipets. 
  • Role of transmethylation reactions in cellular motility and phagocytosis. 
  • Role of water in short-range repulsive and attractive interactions between macromolecules and bilayers. 
  • S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery. 
  • S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. 
  • S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme. 
  • SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. 
  • SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa. 
  • SNAP-mediated protein-protein interactions essential for neurotransmitter release. 
  • SOCS3 inhibiting migration of A549 cells correlates with PYK2 signaling in vitro. 
  • Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses. 
  • Saphenous vein endothelium-dependent relaxation in patients with peripheral vascular disease. 
  • Screening of potential reproductive toxicants by use of porcine granulosa cell cultures. 
  • Secondary structure creates mismatched base pairs required for high-affinity binding of cAMP response element-binding protein to the human enkephalin enhancer. 
  • Secretin receptors mediating rat forestomach relaxation. 
  • Seizure activity in vitro: a dual focus model. 
  • Seizure-like activity disrupts LTP in vitro. 
  • Seizure-like events in brain slices: suppression by interictal activity. 
  • Seizure-like spreading depression in immature rabbit hippocampus in vitro. 
  • Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1. 
  • Selective alteration in high affinity agonist binding: a mechanism of beta-adrenergic receptor desensitization. 
  • Selective autoregulation of endothelins in primary astrocyte cultures: endothelin receptor-mediated potentiation of endothelin-1 secretion. 
  • Selective expression of the small GTPase RhoB in the early developing mouse lens. 
  • Selective gamma-aminobutyric acid type A receptor antagonism reverses isoflurane ischemic neuroprotection. 
  • Selective increase in L-[3H]glutamate binding to a quisqualate-sensitive site on hippocampal synaptic membranes after angular bundle kindling. 
  • Selective suppression of in vitro electrographic seizures by low-dose tetrodotoxin: a novel anticonvulsant effect. 
  • Selectivity of dobutamine for adrenergic receptor subtypes: in vitro analysis by radioligand binding. 
  • Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B. 
  • Sensory neuron signaling to the brain: properties of transmitter release from olfactory nerve terminals. 
  • Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion. 
  • Serum obstruction of aqueous outflow in enucleated eyes. 
  • Setting positive end-expiratory pressure during jet ventilation to replicate the mean airway pressure of oscillatory ventilation. 
  • Sex steroid hormones enhance immune function in male and female Siberian hamsters. 
  • Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling. 
  • Short-chain alkyl esters of L-dopa as prodrugs for rectal absorption. 
  • Short-term frequency-dependent plasticity at recurrent mossy fiber synapses of the epileptic brain. 
  • Short-term regulation of Na+/K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cells. 
  • Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms. 
  • Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage. 
  • Signaling by olfactory receptor neurons near threshold. 
  • Significant left ventricular contribution to right ventricular systolic function. 
  • Simultaneous labeling of mast cell proteases and protease mRNAs at the bone-implant interface of aseptically loosened hip implants. 
  • Simultaneous measurement of cytochrome a3 reduction and chemoreceptor afferent activity in the carotid body. 
  • Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices. 
  • Simultaneous optical recording of evoked and spontaneous transients of membrane potential and intracellular calcium concentration with high spatio-temporal resolution. 
  • Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. 
  • Site of Tc-99m binding to the red blood cell: concise communication. 
  • Site-specific RNA cleavage generates the 3' end of a poxvirus late mRNA. 
  • Site-specific effects of compression on macromolecular diffusion in articular cartilage. 
  • Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching. 
  • Slime production, adherence and hydrophobicity in coagulase-negative staphylococci causing peritonitis in peritoneal dialysis. 
  • Slow NMDA-EPSCs at synapses critical for song development are not required for song learning in zebra finches. 
  • Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy. 
  • Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. 
  • Sodium-independent binding of L-[3H]proline to hippocampal synaptic membranes. 
  • Solubilization of a [3H]cimetidine binding site from rat brains. A clonidine-sensitive H-2 receptor subtype? 
  • Somatomedin-C stimulates glycogen synthesis in fetal rat hepatocytes. 
  • Somatostatin receptor subtype 4 couples to the M-current to regulate seizures. 
  • Spatial control of membrane potential: a method for improved voltage clamping of the squid giant synapse. 
  • Spatial performance correlates with in vitro potentiation in young and aged Fischer 344 rats. 
  • Spatial profiles of electrical mismatch determine vulnerability to conduction failure across a host-donor cell interface. 
  • Species differences in susceptibility to 1,3-dinitrobenzene-induced testicular toxicity and methemoglobinemia. 
  • Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species. 
  • Specific PGF(2alpha) receptor (FP) antagonism and human uterine contractility in vitro. 
  • Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment. 
  • Specific innervation of guinea-pig superior cervical ganglion cells by preganglionic fibres arising from different levels of the spinal cord. 
  • Specificity and regulation of a synaptic vesicle docking complex. 
  • Specificity of initial synaptic contacts made on guinea-pig superior cervical ganglion cells during regeneration of the cervical sympathetic trunk. 
  • Spermine. A regulator of mitochondrial calcium cycling. 
  • Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action. 
  • Spin labeled acetylcholine analogs: studies of cholinergic receptor. 
  • Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. 
  • Spinal dorsal horn neurons in elevated extracellular calcium: cell properties and spontaneous discharges. 
  • Spontaneous activity induced in isolated mouse spinal cord by high extracellular calcium and by low extracellular magnesium. 
  • Spontaneous delta- to beta-globin switching in K562 human leukemia cells. 
  • Spontaneous neuronal firing patterns in fetal rat cortical networks during development in vitro: a quantitative analysis. 
  • Spontaneous re-aggregation of IgM subunits and restoration of antibody activity after reduction and alkylation of rabbit anti-Forssman antibody. 
  • Spreading depression-like hypoxic depolarization in CA1 and fascia dentata of hippocampal slices: relationship to selective vulnerability. 
  • Stage-dependent toxicity of N-acetyl-glucosamine to Plasmodium falciparum. 
  • Statistical hemodynamics: a tool for evaluating the effect of fluid dynamic forces on vascular biology in vivo. 
  • Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle. 
  • Steady state kinetics of soluble and membrane-bound mitochondrial ATPase. 
  • Steady-state fluorescence imaging of neoplasia. 
  • Stem cell factor is a potent synergistic factor in hematopoiesis. 
  • Stereochemistry of the reactions catalyzed by chicken liver fatty acid synthase. 
  • Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist. 
  • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. 
  • Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP). 
  • Steroidal modulation of steroid secretion in vitro: an experimental approach to intra-follicular regulatory mechanisms. 
  • Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. 
  • Stimulation of in vitro proliferation of murine lymphocytes by synthetic oligodeoxynucleotides. 
  • Stimulation of long-chain fatty acid uptake by dipyridamole in isolated myocytes. 
  • Strain patterns in the patellar tendon and the implications for patellar tendinopathy. 
  • Stretch-regulated exocytosis/endocytosis in bladder umbrella cells. 
  • Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding. 
  • Structural and functional properties of the "hairy" cells of leukemic reticuloendotheliosis. 
  • Structural and functional response of toad urinary bladder to LiCl. 
  • Structural characteristics for inhibition of [3H] norepinephrine uptake into rat brain synaptic vesicles by beta-carboline, indolealkylamine, phenethylamine and n-alkylamine derivatives. 
  • Structure and biological activity of (-)-[3H]dihydroalprenolol, a radioligand for studies of beta-adrenergic receptors. 
  • Structure and expression of a membrane component of the inhibin receptor system. 
  • Structure-activity relationships for the reserpine-like actions of derivatives of beta-carboline in vitro. 
  • Structure-activity relationships of 2-aminotetralins and 2-aminoindanes: inhibitory neuroeffector mechanisms in isolated guinea-pig ilea. 
  • Structure-activity relationships of adenylate cyclase-coupled beta adrenergic receptors: determination by direct binding studies. 
  • Structure-activity relationships of noreperidine congeners on cholinesterase systems in vitro and analgesia in vivo. 
  • Studies of human and monkey "epileptic" neocortex in the in vitro slice preparation. 
  • Studies of phagocytosis in chronic granulomatous disease. 
  • Studies on cellular autophagocytosis. The relationship of autophagocytosis to protein synthesis and to energy metabolism in rat liver and flounder kidney tubules in vitro. 
  • Studies on the in vivo effects of antibody. Interaction of IgM antibody and complement in the immune clearance and destruction of erythrocytes in man. 
  • Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. 
  • Subclassification of alpha-adrenergic receptors by direct binding studies. 
  • Subcutaneous infusion of human C1 inhibitor in swine. 
  • Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro. 
  • Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. 
  • Substance P dependence of endosomal fusion during bladder inflammation. 
  • Substance P primes human neutrophil activation: a mechanism for neurological regulation of inflammation. 
  • Substituted 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-ones as potential antiinflammatory agents. 
  • Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors. 
  • Substrate-bound nerve growth factor promotes neurite growth in peripheral nerve. 
  • Subthreshold synaptic Ca2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons. 
  • Subtype-specific binding of azidoanilido-GTP by purified G protein alpha subunits. 
  • Summarizing the motion of self-propelled cells: applications to sperm motility. 
  • Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. 
  • Suppression of interictal bursting in hippocampus unleashes seizures in entorhinal cortex: a proepileptic effect of lowering [K+]o and raising [Ca2+]o. 
  • Suppression of large intraluminal bubble expansion in shock wave lithotripsy without compromising stone comminution: methodology and in vitro experiments. 
  • Suppression of presynaptic calcium currents by hypoxia in hippocampal tissue slices. 
  • Suppression of repetitive firing of neurons by diphenylbarbituric acid. 
  • Suppressor function of T lymphocytes in the acquired immunodeficiency syndrome as assessed by allogeneic mixed lymphocyte culture. 
  • Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex. 
  • Supramicron-sized particle clearance from alveoli: route and kinetics. 
  • Supratrigeminal Bilaterally Projecting Neurons Maintain Basal Tone and Enable Bilateral Phasic Activation of Jaw-Closing Muscles. 
  • Surface proteins of a transitional carcinoma cell line (KS-31E). 
  • Susceptibility tensor imaging of the kidney and its microstructural underpinnings. 
  • Sustained release of plasmid DNA using lipid microtubules and agarose hydrogel. 
  • Swelling and curling behaviors of articular cartilage. 
  • Symmetry of the inhibitory unit of human alpha 2-macroglobulin. 
  • Synapsins differentially control dopamine and serotonin release. 
  • Synaptic activation of presynaptic glutamate transporter currents in nerve terminals. 
  • Synaptic basis for developmental plasticity in a birdsong nucleus. 
  • Synaptic connections from multiple subfields contribute to granule cell hyperexcitability in hippocampal slice cultures. 
  • Synaptic development in brains of rats exposed perinatally to ethanol. 
  • Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds. 
  • Synergistic disaggregation of platelets by tissue-type plasminogen activator, prostaglandin E1, and nitroglycerin. 
  • Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro. 
  • Synthesis and NK(1)/NK(2) binding activities of a series of diacyl-substituted 2-arylpiperazines. 
  • Synthesis and characterization of 4-methoxy-7-nitroindolinyl-D-aspartate, a caged compound for selective activation of glutamate transporters and N-methyl-D-aspartate receptors in brain tissue. 
  • Synthesis and dopaminergic properties of benzo-fused analogues of quinpirole and quinelorane. 
  • Synthesis and evaluation of a novel series of 2-chloro-5-((1-methyl-2-(S)-pyrrolidinyl)methoxy)-3-(2-(4-pyridinyl)vinyl)pyridine analogues as potential positron emission tomography imaging agents for nicotinic acetylcholine receptors. 
  • Synthesis and preliminary biological evaluation of (3-iodobenzoyl)norbiotinamide and ((5-iodo-3-pyridinyl)carbonyl)norbiotinamide: two radioiodinated biotin conjugates with improved stability. 
  • Synthesis and receptor affinities of some conformationally restricted analogues of the dopamine D1 selective ligand (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl- 1H-3-benzazepin-7-ol. 
  • Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography. 
  • Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. 
  • Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. 
  • Synthetic biology looks good on paper. 
  • Systemic hypertension alters vasomotor function in experimental vein grafts. 
  • Systemic soluble Tie2 expression inhibits and regresses corneal neovascularization. 
  • TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction. 
  • TRPV4 channels augment macrophage activation and ventilator-induced lung injury. 
  • TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. 
  • Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models. 
  • Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. 
  • Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. 
  • Temperature-sensitive polymer-nanoshell composites for photothermally modulated drug delivery 
  • Temporal alterations in peripheral vascular responsiveness during both the development and recovery from pacing-induced heart failure. 
  • Tensile properties of nondegenerate human lumbar anulus fibrosus. 
  • The ATM-dependent DNA damage signaling pathway. 
  • The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. 
  • The COOH-terminal domain of the Rap1A (Krev-1) protein is isoprenylated and supports transformation by an H-Ras:Rap1A chimeric protein. 
  • The COPI complex functions in nuclear envelope breakdown and is recruited by the nucleoporin Nup153. 
  • The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. 
  • The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. 
  • The E2F transcription factor is a cellular target for the RB protein. 
  • The Flk1-myr::mCherry mouse as a useful reporter to characterize multiple aspects of ocular blood vessel development and disease. 
  • The Schultz-Dale response of sensitized canine bronchial smooth muscle. 
  • The ability of certain SIV vaccines to provoke reactions against normal cells. 
  • The action of hydrogen peroxide on paired pulse and long-term potentiation in the hippocampus. 
  • The action of oxygen and oxygen at high pressure on inhibitory transmission. 
  • The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals. 
  • The aromatase enzyme: from cloning to cancer. 
  • The auxiliary subunit KChIP2 is an essential regulator of homeostatic excitability. 
  • The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. 
  • The biological differentiation of 99-Mo and 99-Tcm in rabbits and its effect on the gamma-counting rate of plasma samples. 
  • The biological properties of insulins with tyrosine replaced by phenylalanine at positions 14 and 19 of the A chain. 
  • The case of the missing NO-hemoglobin: spectral changes suggestive of heme redox reactions reflect changes in NO-heme geometry. 
  • The chloride transporter Na(+)-K(+)-Cl- cotransporter isoform-1 contributes to intracellular chloride increases after in vitro ischemia. 
  • The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment. 
  • The conformation of the active site of myosin probed using mant-nucleotides. 
  • The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors. 
  • The differential effect of in vivo hydrocortisone on the kinetics of subpopulations of human peripheral blood thymus-derived lymphocytes. 
  • The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. 
  • The drug MK-801 attenuates the development, but not the expression, of long-term potentiation and stimulus train-induced bursting in hippocampal slices. 
  • The dual nature of human extracellular superoxide dismutase: one sequence and two structures. 
  • The effect of PIXY-321 on 4-hydroperoxycyclophosphamide purged and CD34+ positively selected bone marrow. 
  • The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro. 
  • The effect of cardiac compression on defibrillation efficacy and the upper limit of vulnerability. 
  • The effect of changing extracellular potassium concentration on synaptic transmission in isolated spinal cords. 
  • The effect of chlorothiazide on neurally mediated contraction of rabbit bronchial smooth muscle. 
  • The effect of cocaine on sperm motility characteristics and bovine cervical mucus penetration. 
  • The effect of compound 48/80 on contractions induced by toluene diisocyanate in isolated guinea-pig bronchus. 
  • The effect of divalent cations on the conformation and function of human plasminogen. 
  • The effect of drug-induced thrombocytopenia on direct-current transcatheter electrocoagulation. 
  • The effect of ethyl alcohol on isolated human myometrium. 
  • The effect of graded hypertonia on interstitial volume, tissue resistance and synaptic transmission in rat hippocampal tissue slices. 
  • The effect of hypothermia on calculated values using saline and automated air tonometry. 
  • The effect of interstitial air on the in vitro thrombogenicity of ePTFE vascular grafts. 
  • The effect of intraocular irrigating solutions on lens clarity in normal and diabetic rabbits. 
  • The effect of phosphoramidon and epithelium removal on toluene diisocyanate-induced contractions in guinea-pig bronchi. 
  • The effect of the perflubron emulsion Oxygent on the calibration characteristics of polarographic oxygen electrodes. 
  • The effect of tibiofemoral joint kinematics on patellofemoral contact pressures under simulated muscle loads. 
  • The effects of IL-1, IL-2, and tumor necrosis factor on polymorphonuclear leukocyte Fc gamma receptor-mediated phagocytosis. IL-2 down-regulates the effect of tumor necrosis factor. 
  • The effects of aging, antiinflammatory drugs, and ultrasound on the in vitro response of tendon tissue. 
  • The effects of argatroban on thrombin generation and hemostatic activation in vitro. 
  • The effects of baclofen and pertussis toxin on epileptiform activity induced in the hippocampal slice by magnesium depletion. 
  • The effects of cholecystokinin and cholecystokinin antagonists on synaptic function in the CA1 region of the rat hippocampal slice. 
  • The effects of mechanical loading and gadolinium concentration on the change of T1 and quantification of glycosaminoglycans in articular cartilage by microscopic MRI. 
  • The effects of moderate changes of extracellular K+ and Ca2+ on synaptic and neural function in the CA1 region of the hippocampal slice. 
  • The effects of padded surfaces on the risk for cervical spine injury. 
  • The effects of post-ganglionic axotomy on selective synaptic connexions in the superior cervical ganglion of the guinea-pig. 
  • The effects of quinidine and verapamil on electrically induced automaticity in the ventricular myocardium of guinea pig. 
  • The effects of temperature on synaptic transmission in hippocampal tissue slices. 
  • The effects of toluene diisocyanate and of capsaicin on human bronchial smooth muscle in vitro. 
  • The efficacy and safety of lenalidomide plus dexamethasone in relapsed and/or refractory multiple myeloma patients with impaired renal function. 
  • The elimination of redundant preganglionic innervation to hamster sympathetic ganglion cells in early post-natal life. 
  • The ethics of experimenting with human brain tissue. 
  • The eukaryotic translation initiation factor 4E is not modified during the course of vaccinia virus replication. 
  • The extent and mechanism of the loss of function caused by strongly hypotonic solutions in rat hippocampal slices. 
  • The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace. 
  • The hemodynamics of thrombus formation in arteries. 
  • The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis. 
  • The human cytokine I-309 is a monocyte chemoattractant. 
  • The impact of aging on adrenergic receptor function: clinical and biochemical aspects. 
  • The in vitro effects of antithrombin III on the activated coagulation time in patients on heparin therapy. 
  • The in vitro growth of murine high proliferative potential-colony forming cells is not enhanced by growth in a low oxygen atmosphere. 
  • The in vitro reversal of histamine-induced vasodilation in the human internal mammary artery. 
  • The influence of inhalational anesthetics on in vivo and in vitro benzodiazepine receptor binding in the rat cerebral cortex. 
  • The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. 
  • The intrinsic antiretroviral factor APOBEC3B contains two enzymatically active cytidine deaminase domains. 
  • The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines. 
  • The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function. 
  • The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro. 
  • The lack of involvement of cyclic nucleotides in the smooth muscle relaxant action of BRL 34915. 
  • The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. 
  • The mechanisms and analysis of sperm migration through cervical mucus. 
  • The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. 
  • The molecular basis of class II MHC allelic control of T cell responses. 
  • The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model. 
  • The neuromuscular blocking effects of therapeutic concentrations of various antibiotics on normal rat skeletal muscle: a quantitative comparison. 
  • The pathway mediating insulin's effects on pyruvate dehydrogenase bypasses the insulin receptor tyrosine kinase. 
  • The perfusion of isolated whole organs. 
  • The pharmacology of aminoadamantane nitrates. 
  • The potential gradient field created by epicardial defibrillation electrodes in dogs. 
  • The protein binding of timegadine determined by equilibrium dialysis. 
  • The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis. 
  • The question of cholinergic antagonism. 
  • The rapid and large scale separation of peritoneal macrophages. 
  • The relationship between the myocardial kinetics of meperidine and its effect on myocardial contractility: model-independent analysis and optimal regional model. 
  • The relaxant effect of diazoxide on isolated gravid and nongravid human myometrium. 
  • The resolution, isolation, and pharmacological characterization of the enantiomers of a benzamide containing a chiral sulfoxide. 
  • The role of F-actin in hypo-osmotically induced cell volume change and calcium signaling in anulus fibrosus cells. 
  • The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice. 
  • The role of calcium ions in the suppression of the photoresponse during anoxia and application of metabolic inhibitors. 
  • The role of free fatty acids in the regulation of lipolysis by human adipose tissue cells. 
  • The role of glutathione reductase in maintaining human granulocyte function and sensitivity to exogenous H2O2. 
  • The role of leukotriene B4 in Clostridium difficile toxin A-induced ileitis in rats. 
  • The role of ligand-ligand interactions in competition by fibrinogen and fibrin degradation products for fibrinogen binding to human platelets. 
  • The role of ribosomal subunits and 80-S monomers in polysome formation in an ascites tumour cell. 
  • The role of spatial interactions in creating the dispersion of transmembrane potential by premature electric shocks. 
  • The role of surface ig binding in the activation of human B cells by phosphorothioate oligodeoxynucleotides. 
  • The selective serotonin reuptake inhibitor citalopram induces the storage of serotonin in catecholaminergic terminals. 
  • The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells. 
  • The soluble metalloendoprotease required in myoblast fusion remains intracellular. 
  • The sources of extracellular potassium accumulation in the CA1 region of hippocampal slices. 
  • The sylvian aqueduct syndrome. A clinicopathologic study. 
  • The transient appearance of specific proteins in one-cell mouse embryos. 
  • The use of magnetic resonance imaging to track controlled drug release and transport in the brain. 
  • The vasodilator effects of clevidipine on human internal mammary artery. 
  • The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. 
  • The viscosity of neutrophils and their transit times through small pores. 
  • The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. 
  • Three-dimensional characterization of the femoral footprint of the posterior cruciate ligament. 
  • Three-dimensional membrane crystals in amphibian cone outer segments. 1. Light-dependent crystal formation in frog retinas. 
  • Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin. 
  • Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states. 
  • Thromboxane A2 analogue contracts predominantly the hepatic veins in isolated canine liver. 
  • Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells. 
  • Thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, ATPase activities, and sialic acid content of rat cardiac membrane vesicles. 
  • Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules. 
  • Time-dependent recovery of passive neutrophils after large deformation. 
  • Time-resolved optical tomography using short-pulse laser for tumor detection. 
  • Tissue type-specific expression of the dsRNA-binding protein 76 and genome-wide elucidation of its target mRNAs. 
  • Toll-like receptor 3 and geographic atrophy in age-related macular degeneration. 
  • Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts. 
  • Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse. 
  • Topoisomerase II levels during granulocytic maturation in vitro and in vivo. 
  • Total internal reflection fluorescence microscopy (TIRFM). II. Topographical mapping of relative cell/substratum separation distances. 
  • Toxic effects of catecholamines on skin. 
  • Trade-offs during the development of primary and secondary sexual traits in a horned beetle. 
  • Trans-splicing reactions by ribozymes. 
  • Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin. 
  • Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B lymphocytes. 
  • Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. 
  • Transgenic mice overproducing islet amyloid polypeptide have increased insulin storage and secretion in vitro. 
  • Transient oscillation of cavitation bubbles near stone surface during electrohydraulic lithotripsy. 
  • Translational inhibition of messenger RNA of the human pi class glutathione S-transferase by antisense oligodeoxyribonucleotides. 
  • Transport pathways in rat lingual epithelium. 
  • Transscleral diffusion of ethacrynic acid and sodium fluorescein. 
  • Transthyretin sequesters amyloid beta protein and prevents amyloid formation. 
  • Treatment of experimental disseminated candidiasis with cilofungin. 
  • Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier. 
  • Trout liver slices for metabolism and toxicity studies. 
  • Trypsin digestion increases Na(+)-H+ exchange rates in native rabbit brush border membrane. 
  • Tumor membrane lymphocyte stimulation assay in patients with renal cell carcinoma. 
  • Tumor necrosis factor-alpha-induced lung injury and its modulation by synthetic polynucleotide: a physiologic-morphometric analysis. 
  • Tuning magnesium sensitivity of BK channels by mutations. 
  • Two different mechanisms underlie reversible, intrinsic optical signals in rat hippocampal slices. 
  • Two mechanisms that raise free intracellular calcium in rat hippocampal neurons during hypoosmotic and low NaCl treatment. 
  • Two temporal phases of light adaptation in retinal rods. 
  • Two-photon molecular excitation imaging of Ca2+ transients in Langendorff-perfused mouse hearts. 
  • Tyrosine phosphorylation in human neutrophil. 
  • Unconventional serotonergic excitation in Aplysia. 
  • Upregulation of PAI-1 is mediated through TGF-beta/Smad pathway in transplant arteriopathy. 
  • Uptake and retention kinetics of para-fluorine-18-fluorobenzylguanidine in isolated rat heart. 
  • Uptake of itraconazole by alveolar macrophages. 
  • Uptake of proline by brushborder vesicles isolated from human kidney cortex. 
  • Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening. 
  • Use of cell fusion techniques to probe the mechanism of catecholamine-induced desensitization of adenylate cyclase in frog erythrocytes. 
  • Use of intrinsic optical signals to monitor physiological changes in brain tissue slices. 
  • Use of perfluorocarbon nanoparticles for non-invasive multimodal cell tracking of human pancreatic islets. 
  • Use of pharmacogenetics to guide warfarin therapy. 
  • Use of poly-l-aspartic acid to inhibit aminoglycoside cochlear ototoxicity. 
  • Use of resampling techniques to estimate the variance of parameters in pharmacological assays when experimental protocols preclude independent replication: an example using Schild regressions. 
  • Using antifibrinolytics in the peripartum period - concern for a hypercoagulable effect? 
  • Uterine relaxant properties of bradykinin in vitro. 
  • VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. 
  • Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice. 
  • Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. 
  • Validation of 4-[fluorine-18]fluoro-3-iodobenzylguanidine as a positron-emitting analog of MIBG. 
  • Vascular release of nonheme iron in perfused rabbit lungs. 
  • Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II. 
  • Vasoactive effects of substance P on isolated rabbit pulmonary artery. 
  • Virtual electrode effects in transvenous defibrillation-modulation by structure and interface: evidence from bidomain simulations and optical mapping. 
  • Viscosity of passive human neutrophils undergoing small deformations. 
  • Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase. 
  • Vitamin K enhancement of sorafenib-mediated HCC cell growth inhibition in vitro and in vivo. 
  • Voltage clamp analysis of pentylenetetrazol effects on Aplysia neurons. 
  • Voltage clamp discloses slow inward current in hippocampal burst-firing neurones. 
  • Voltage-dependent action of valproate on potassium channels in frog node of Ranvier. 
  • Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro. 
  • Volume and osmotic properties of human neutrophils. 
  • Vulnerability in an excitable medium: analytical and numerical studies of initiating unidirectional propagation. 
  • Waveform and amplitude characteristics of evoked responses to dendritic stimulation of CA1 guinea-pig pyramidal cells. 
  • Whole-cell membrane current and membrane resistance during hypoxic spreading depression. 
  • Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection. 
  • Work in progress: in vitro analysis of pleural fluid analogs by proton magnetic resonance. Preliminary studies at 1.5T. 
  • Workshop on monoclonal antibodies against gliomas and other neuroectoderm-derived tumors. 
  • X-ray diffraction and electron microscopy from Lethocerus flight muscle partially relaxed by adenylylimidodiphosphate and ethylene glycol. 
  • X-ray diffraction indicates that active cross-bridges bind to actin target zones in insect flight muscle. 
  • X-ray evidence that in contracting live frog muscles there exist two distinct populations of myosin heads. 
  • Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. 
  • Zeta-crystallin from guinea pig lens is capable of functioning catalytically as an oxidoreductase. 
  • Zone electrophoresis and prolactin activity of rat adenohypophysis cultivated in vitro. 
  • [3H]Dihydroergocryptine binding to alpha adrenergic receptors in canine aortic membranes. 
  • [3H]WB4101--caution about its role as an alpha-adrenergic subtype selective radioligand. 
  • [3H]acetylcholine binding sites in brain. Effect of disulfide bond modification. 
  • [Different effects of typical and atypical neuroleptics on K+-stimulated dopamine release from isolated rat striatum]. 
  • [Effect of aspartic acid derivatives, N-acetyl-aspartate and its phosphonic analog PIR-87-6-0, on dopamine release from the rat striatum during perfusion in vitro] 
  • [Effects of haloperidol on extracellular contents of dopamine and its metabolites in the septum of rats during interspecies aggression] 
  • [Identification and evaluation of properties of benzodiazepine receptors of glial and neuronal fractions of human cerebral cortex]. 
  • [Slow excitation waves and mechanisms of polymorphic ventricular tachycardia in an experimental model: isolated walls of the right ventricle from rabbit and squirrel] 
  • [Study by the intracerebral microdialysis method of the effects of atypical neuroleptics and anxiolytics on striatal release and metabolism of dopamine in awake rats]. 
  • [The effect of a low dose of piracetam on the activity of the dopaminergic system in the rat striatum]. 
  • alpha-Adrenergic receptors in rat parotid cells. I. Correlation of [3H]dihydroergocryptine binding and catecholamine-stimulated potassium efflux. 
  • alpha-Adrenergic receptors in rat parotid cells. II. Desensitization of receptor binding sites and potassium release. 
  • beta-Adrenergic receptor regulation by agonists and membrane depolarization in rat brain slices. 
  • beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. 
  • beta-Endorphin enhances the replication of neurotropic human immunodeficiency virus in fetal perivascular microglia. 
  • beta-adrenergic receptors in brown adipose tissue: identification by (-)[3H]dihydroalprenolol binding. 
  • beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. 
  • cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain synaptoneurosomes. 
  • cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes. 
  • cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation. 
  • gamma-Aminobutyrate, alpha-carboxy-2-nitrobenzyl ester selectively blocks inhibitory synaptic transmission in rat dentate gyrus. 
  • p-Chlorophenylalanine-induced enhancement of the effects of morphine on the adrenal medulla. 
  • β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility.