Pharmacology & Cancer Biology

• 

  People

  • Administrative Positions

    • Casey, Patrick John, Director of the Center for Chemical Biology
    • Duckett, Colin S, Vice Dean for Basic Science

  • Faculty Positions

    • Semesta, Khairunnisa Mentari, Instructor, Special Programs

  • Professorships

    • Casey, Patrick John, James B. Duke Distinguished Professor of Pharmacology and Cancer Biology
    • Counter, Christopher M., George Barth Geller Distinguished Professor of Pharmacology
    • Kastan, Michael Barry, William and Jane Shingleton Distinguished Professor of Pharmacology and Cancer Biology
    • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine
    • Means, Anthony Ross, Nanaline H. Duke Distinguished Professor Emeritus of Pharmacology, in the School of Medicine
    • Newgard, Christopher Bang, W. David and Sarah W. Stedman Distinguished Professor of Nutrition in the School of Medicine
    • Pendergast, Ann Marie, Anthony R. Means Cancer Biology Distinguished Professor
    • Wang, Xiao-Fan, Donald and Elizabeth Cooke Distinguished Professor of Cancer Research, in the School of Medicine

  • Primary Appointments

    • Alvarez, James Valerinano, Adjunct Assistant Professor in the Department of Pharmacology & Cancer Biology
    • Anderson, Kristin Ann, Assistant Research Professor of Pharmacology & Cancer Biology
    • Andrews, Nancy Catherine, Adjunct Professor in the Department of Pharmacology and Cancer Biology
    • Cartoni, Romain, Assistant Professor of Pharmacology and Cancer Biology
    • Casey, Patrick John, Professor of Pharmacology and Cancer Biology
    • Chang, Ching-yi, Associate Research Professor of Pharmacology and Cancer Biology
    • Counter, Christopher M., Professor of Pharmacology and Cancer Biology
    • Fox, Donald T, Associate Professor of Pharmacology & Cancer Biology
    • Goetz, Sarah Catherine, Assistant Professor of Pharmacology & Cancer Biology
    • Haystead, Timothy Arthur James, Professor of Pharmacology and Cancer Biology
    • Kastan, Michael Barry, Professor of Pharmacology and Cancer Biology
    • Korach, Kenneth Steven, Adjunct Professor of Pharmacology & Cancer Biology
    • Kuhn, Cynthia Moreton, Professor of Pharmacology and Cancer Biology
    • Locasale, Jason, Associate Professor of Pharmacology and Cancer Biology
    • MacAlpine, David, Professor of Pharmacology and Cancer Biology
    • Mathey-Prevot, Bernard, Adjunct Professor in the Department of Pharmacology & Cancer Biology
    • McDonnell, Donald Patrick, Professor of Pharmacology and Cancer Biology
    • Means, Anthony Ross, Professor Emeritus of Pharmacology & Cancer Biology
    • Nadler, J. Victor, Professor Emeritus of Pharmacology & Cancer Biology
    • Newgard, Christopher Bang, Professor of Pharmacology and Cancer Biology
    • Norris, John David, Associate Research Professor in Pharmacology & Cancer Biology
    • Oliver, Trudy G, Professor of Pharmacology and Cancer Biology
    • Ouyang, Jian, Assistant Research Professor of Pharmacology & Cancer Biology
    • Pendergast, Ann Marie, Professor of Pharmacology and Cancer Biology
    • Rathmell, Jeffrey Charles, Adjunct Associate Professor in the Department of Pharmacology and Cancer Biology
    • Sawyer, Jessica, Assistant Research Professor of Pharmacology and Cancer Biology
    • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology
    • Seidler, Frederic J., Assistant Research Professor Emeritus of Pharmacology & Cancer Biology
    • Slotkin, Theodore Alan, Professor of Pharmacology and Cancer Biology
    • Thompson, J. Will, Adjunct Assistant Professor in the Department of Pharmacology & Cancer Biology
    • Tsvetanova, Nikoleta Georgieva, Assistant Professor of Pharmacology and Cancer Biology
    • VanDongen, Antonius M. J., Associate Professor of Pharmacology & Cancer Biology
    • Wang, Xiao-Fan, Professor of Pharmacology and Cancer Biology
    • Wardell, Suzanne E, Assistant Research Professor of Pharmacology & Cancer Biology
    • West, Andrew Bradley, Professor of Pharmacology and Cancer Biology
    • Wingler, Laura M., Assistant Professor of Pharmacology and Cancer Biology
    • Wood, Kris Cameron, Associate Professor of Pharmacology and Cancer Biology
    • Yao, Tso-Pang, Professor of Pharmacology and Cancer Biology
    • York, John David, Adjunct Professor in the Department of Pharmacology & Cancer Biology
    • Zhang, Zhao, Assistant Professor of Pharmacology and Cancer Biology
    • Zou, Lee, Instructor in the Department of Pharmacology & CancerBiology

  • Secondary Appointments

    • Alman, Benjamin Aaron, Professor in Pharmacology and Cancer Biology
    • Armstrong, Andrew John, Professor in Pharmacology and Cancer Biology
    • Arshavsky, Vadim Y, Professor in Pharmacology & Cancer Biology
    • Bissig, Karl-Dimiter, Associate Professor in Pharmacology and Cancer Biology
    • Blobe, Gerard Conrad, Professor of Pharmacology and Cancer Biology
    • Campbell, Jonathan Edward, Associate Research Professor in Pharmacology & Cancer Biology
    • Chi, Jen-Tsan Ashley, Associate Professor of Pharmacology and Cancer Biology
    • Duckett, Colin S, Professor in Pharmacology and Cancer Biology
    • Floyd, Scott Richard, Assistant Research Professor in Pharmacology and Cancer Biology
    • Hanks, Brent A., Assistant Professor of Pharmacology and Cancer Biology
    • Heitman, Joseph, Professor in Pharmacology & Cancer Biology
    • Hirschey, Matthew, Associate Professor in Pharmacology and Cancer Biology
    • Hong, Jiyong, Associate Professor of Pharmacology and Cancer Biology
    • Huang, Jiaoti, Professor of Pharmacology and Cancer Biology
    • Jordt, Sven Eric, Associate Professor of Pharmacology and Cancer Biology
    • Kontos, Christopher Dale, Professor of Pharmacology and Cancer Biology
    • Kwatra, Madan Mohan, Associate Professor of Pharmacology & Cancer Biology
    • Levin, Edward Daniel, Associate Professor of Pharmacology & Cancer Biology
    • Li, Chuan-Yuan, Professor of Pharmacology and Cancer Biology
    • Linardic, Corinne Mary, Associate Professor of Pharmacology and Cancer Biology
    • MacIver, Nancie Jo, Assistant Professor in Pharmacology and Cancer Biology
    • McNamara Sr., James O'Connell, Professor of Pharmacology and Cancer Biology
    • Muoio, Deborah Marie, Professor in Pharmacology and Cancer Biology
    • Nackley, Andrea Gail, Associate Professor in Pharmacology and Cancer Biology
    • Patierno, Steven, Professor of Pharmacology and Cancer Biology
    • Patz Jr., Edward F., Professor in Pharmacology & Cancer Biology
    • Privratsky, Jamie Rae, Associate Professor in Pharmacology and Cancer Biology
    • Ramanujam, Nimmi, Professor of Pharmacology and Cancer Biology
    • Rao, Ponugoti Vasantha, Professor in Pharmacology and Cancer Biology
    • Roper, Jatin, Assistant Professor in Pharmacology and Cancer Biology
    • Sipkins, Dorothy Anna, Associate Research Professor in Pharmacology and Cancer Biology
    • Snyder, Joshua Clair, Associate Professor in Pharmacology and Cancer Biology
    • Sullenger, Bruce Alan, Professor of Pharmacology and Cancer Biology
    • White, Phillip James, Assistant Research Professor in Pharmacology and Cancer Biology
    • Wu, Colleen, Assistant Research Professor in Pharmacology and Cancer Biology

  • Non-Faculty Positions

    • Akbar, Hameed, Postdoctoral Associate
    • Akef, Abdalla, Research Associate, Senior
    • Artham, Sandeep, Postdoctoral Associate
    • Boddu, Ravindra, Research Scientist
    • Bodoor, Khaldon, Research Scientist
    • Boyce, Michael, Triage Technician
    • Bryant, Nicole, Postdoctoral Associate
    • Chakraborty, Archan, Postdoctoral Associate
    • Chakraborty, Binita, Research Scientist
    • Chen, Bo-Hua, Postdoctoral Associate
    • Chen, Mark, House Staff
    • Duan, Likun, Postdoctoral Associate
    • Edwards, Drake, House Staff
    • Fleenor, Donald, Research Scientist, Senior
    • Gu, Jing Jin, Research Scientist, Senior
    • Hughes, Philip, Research Scientist, Senior
    • Le Roux, Ozgun, Research Associate, Senior
    • Liu, Juan, Research Scientist
    • Liu, Shiyu, Postdoctoral Associate
    • Liu, Zhiyong, Research Associate, Senior
    • Lopez, Omar, Regulatory Affairs Scientist
    • Malankhanova, Tuyana, Postdoctoral Associate
    • Messer, Luke, Postdoctoral Associate
    • Mukherjee, Debarati, Research Associate, Senior
    • Oristian, Kristi, Research Technician II
    • Quade, Bianca, Postdoctoral Associate
    • RAN, XIAOJUAN, Postdoctoral Associate
    • Russell, Shonagh, Postdoctoral Associate
    • Safi, Rachid, Research Scientist
    • Su, Weijia, Postdoctoral Associate
    • Tan, Lianmei, Postdoctoral Associate
    • Whiteley, Andy, Postdoctoral Associate
    • Xu, Enquan, Postdoctoral Associate
    • Yang, Fu, Research Associate, Senior
    • Yao, Shun, Postdoctoral Associate
    • Yin, Tao, Research Associate, Senior
    • Zhang, Yuchen, Postdoctoral Associate
    • Zimmerman, Seth, Research Associate, Senior

  • Affiliate Positions

    • Nguyen, Abraham, Affiliate
    • Pan, Chris, Affiliate
    • Wisdom, Amy, Affiliate

  • Students

    • Acheampong, Nana, Student
    • Aiduk, Michael, Student
    • Barbier, Roberto, Student
    • Bassil, Christopher, Student
    • Bridgwater, Caroline, Student
    • Burrell, Paige, Student
    • Camacho, Jose, Student
    • Caminear, Michael, Student
    • Cerda-Smith, Christian, Student
    • Chen, Bonnie, Student
    • Chen, Ssu-Yu, Student
    • Chung, Oliver, Student
    • Colemon, Ashley, Student
    • Collins, Matt, Student
    • Delaney, Chris, Student
    • deSouza, Beverly, Student
    • Dillon, Kerry, Student
    • Dolan, Emma, Student
    • Garcia, Nina Marie, Student
    • Gunn, Kiana, Student
    • Hall, Katherine, Student
    • Hernandez, Nathaniel, Student
    • Himes, Jonathon, Student
    • Ireland, Abbie, Student
    • Keenan, E. Keith, Student
    • Killarney, Shane, Student
    • Klauer, Matthew, Student
    • Ko, Min-Yu, Student
    • Kristofich, JohnCarlo, Student
    • Lewis, Liam, Student
    • Liang, Yaosi, Student
    • Llanga, Telmo, Student
    • Lock, Ian, Student
    • Lu, Junqi, Student
    • Luck, Meagan, Student
    • Ludwig, Andrea, Student
    • Ma, Savanna, Student
    • Ma, Zhehao, Student
    • McRoberts Amador, Christian, Student
    • Mendes, Elizabeth, Student
    • Niehoff, Taylor, Student
    • Prioleau, Tatiana, Student
    • Prochazka, Patrick, Student
    • Raj, Jude, Student
    • Ramesh, Vijyendra, Student
    • Rawls, Ashleigh, Student
    • Rivera, Angela, Student
    • Robertson, Corrina, Student
    • Scheaffer, Hannah, Student
    • Shields, Christopher, Student
    • Sokratian, Arpine, Student
    • Song, Xirui, Student
    • Stewart, Amy, Student
    • Stewart, Becky, Student
    • Strader, Samuel, Student
    • Su, Chang, Student
    • Towne, Anna, Student
    • Valentine, Vennesa, Student
    • Wang, Mandy, Student
    • Wilkison, Samantha, Student
    • Wu, Pei-Chen, Student
• 

  Administers Grant

  • 27-hydroxycholesterol as a link between obesity and breast cancer pathogenesis
  • A Novel Method to Stop HIV Replication: Inhibition of Human Purine-Utilizing Proteins
  • ABL kinase inhibition in mouse models of metastatic and therapy-resistant lung cancer
  • ABL kinases promote lung cancer brain metastasis through regulation of transcriptional networks
  • ABL-regulated transcriptional and epigenetic networks promote outgrowth of breast cancer metastases revealing novel therapeutic targets
  • ASPARTATE TRANSMISSION
  • Activation & Function Of Human Cam Kinase Iv In T-Cell
  • Activation And Function Of Human Cam Kinase Iv In T Cells
  • Activation And Function Of Human Cam Kinase Iv In T-Cells
  • Adapting K-MDS to detect KRAS-mutant ctDNA
  • Adolescent Vulnerability to Neuroplastic Changes Induced by High Dose Cocaine.
  • Alcohol, Puberty, and Adolescent Brain Development
  • Analysis Of Bcr/Abl Signaling In Human Leukemias
  • Analysis Of Tgf Beta Receptor Ii Signalling Mechanism
  • Analysis Of Tgf-B Receptor Ii Signalling Mechanism
  • Analysis of Rad17-mediated Checkpoint Signaling
  • Analysis of mechanisms associated with Her2-positive breast cancer resistance to therapy
  • Analysis of the Functional Role of TPF in Tumorigenesis
  • Androgen Receptor Cofactor Profiling of Nido AR Ligands
  • Androgen receptor degradation as a therapeutic modality in castrate resistant prostate cancer
  • Apoptosome Regulation in Leukemia by Protein Phosphatase 5 Hypoacetylation
  • Apoptotic Signaling Pathways
  • Assessment of TTBK2 inhibition by a TTBK-selective kinase inhibitor and identification of TTBK2 substrates
  • Awakening the dormant tumor: the role of the tumor microenvironment in breast cancer recurrence
  • B cell metabolism in activation and autoantibody production
  • BCR-Abl-mediated inhibition of apoptosis
  • Bcr/Abl Signaling In Human Leukemias
  • Behavioral Neuroscience
  • Biological Actions Of 1,25 Dixydroxy-Vitamin D3
  • Biological Aspects Of 1,25 (Oh)2 D3
  • Biological Oscilloscopes: Spatio-Temporal Metabolomics
  • Biological Roles of the Prolyl Isomerase, PIN1
  • Biology Of The Testis
  • Biology Of The Testis
  • Bringing Real Experiments (REX) about Substance Abuse to High School Students
  • Broken chromosome segregation during mitosis: a Drosophila model
  • CaM Kinase Cascades in Endocrine Cells
  • CaMKK2 inhibition as an approach to increase tumor immunity in breast cancers
  • CaMKK2: a druggable target that regulates macrophage function in breast cancer
  • Calcium desensitization in Smooth Muscle.
  • Cancer Biology
  • Cancer Biology Training Grant
  • Cancer Biology Training Grant
  • Cancer cell intrinsic and extrinsic actions of steroid hormones in breast tumors
  • Cellular Stress Response Signaling Pathways
  • Characterization and functional analysis of PPMI LRRK2 variants
  • Characterization of N-Chimaerin
  • Characterization of compartmentalized GPCR signaling in neurons
  • Characterization of the local mitochondria proteomic signature of neurodegeneration
  • Characterizing the role of TTBK proteins in ciliogenesis and neural function
  • Chromatin Modulation Associated with DNA Breakage and Repair in Human Cells
  • Chromatin architecture defines DNA replication origins
  • Chromatin-mediated mechanisms of genome integrity
  • Co-crystalization of inducible Heat shock Protein 70 with the inhibitor HS-72 and structural analogs.
  • Co-crystallization of Hsp70i and the inhibitor HS-72
  • Control Of Neuronal Firing By Adaptation
  • Control of Mitotic Entry by Regulators of Cdc2
  • Control of P53 Tumor Suppressor by CBP/p300
  • Control of The Mitotic Exit by the Xnf7 Ubiquitin Ligase
  • Control of caspase activation in apoptosis
  • Control of lymphocyte trophic state by extrinsic signals
  • Control of the apoptosome in epithelial ovarian cancer to enhance chemotherapy
  • Coordinating Center for the NCI Small Cell Lung Cancer Research Consortium
  • Copper reduction as a novel therapy in BRAF-mutant positive cancers
  • Customs Plasmids Project
  • Deciphering the local effect of glaucoma risk factors on axonal mitoproteome
  • Decoding human genetic variation by functional dissection of beta2-adrenergic receptor signaling
  • Defining biochemical mechanisms of dominant interference by disease-causing variants of TTBK2
  • Defining RAS isoform- and mutation-specific roles in oncogenesis
  • Defining RAS isoform- and mutation-specific roles in oncogenesis
  • Defining RAS isoform- and mutation-specific roles in oncogenesis
  • Defining The Human DNA Replication Program-First Resubmission
  • Defining chromatin architecture and maturation at sites of DNA replication in the Drosophila melanogaster genome
  • Defining the Mechanistic Determinants of Response to Selective Electron Transport Chain Inhibition in Cancer
  • Dentate Granule Cell Network in Epilepsy
  • Designing durable apoptosis-targeting therapies for acute myeloid leukemia
  • Determination of the antiandrogenic properties of VT-464 in models of CRPC
  • Determination of the antiandrogenic properties of VT-464, a novel CYP17 lyase inhibitor
  • Determine the potential therapeutic effect of HDAC6 inhibitors in inhibiting breast cancer metastasis and glioblastoma growth in mouse models
  • Developing in vivo active probes for CAMKK2 to treat cancer
  • Developing inhibitors of RalA function for the treatment of pancreatic cancer
  • Development and Use of Systems to Study Estrogen Action
  • Development of Novel ERRalpha Antagonists as Breast Cancer Therapeutics
  • Development of Tethered Hsp90 Inhibitors Carrying Radioiodinated Probes to Specifically Descriminate and Kill Malignant Breast Tumor Cells
  • Development of an oral targeted drug for treatment of bartonelloses
  • Development of mechanistically distinct androgen receptor antagonists and degraders for the treatment of advanced castration resistant prostate cancer
  • Development of peptide antagonists of estrogen signaling
  • Developmental and Injury Regulation of Polyploidy in the Drosophila Heart
  • Developmental neurotoxicity in Offspring Following Combined Maternal Exposure to Nocotine and Chlorpyrifo
  • Dietary methionine and cancer
  • Does Loss of ATM Suppression of the SMG1 Kinase Contribute to the A-T Phenotype?
  • Dopamine Function During Adolescence
  • Drugs And Development Of Adrenergic Nervous System
  • Drugs And Development Of Adrenergic Nervous System(Supp)
  • Drugs And Development Of The Adrenergic Nervous System
  • Drugs And The Development Of The Nervous System
  • Drugs and Development of the Adrenergic Nervous System
  • Drugs: Integrating High School Biology And Chemistry
  • Duke-Va Center For Cerebrovascular Research/Catecholamine
  • Dynamic requirements of Ras signaling during cancer
  • EPA STAR Fellowship - Melissa Garofolo
  • ER and LXR as mediators of the pathobiology of hypercholesterolemia
  • Ectopic Granule Cells in Epilepsy
  • Effects of dietary methionine restriction on tumor growth and epigenetics
  • Efficacies and Pharmacodynamic Assays for LRRk2 Small-Molecule Inhibitors
  • Elucidating the Role of Kras Specificity Determinants in Pancreatic Cancer
  • Elucidation of the mechanisms by which cells recognize and respond to different levels of androgens
  • Engineering tyrosine kinase-activated caspases for selective cancer cell killing
  • Enhancing Treg Therapeutic Efficacy in GVHD
  • Erythroid Iron Transport
  • Estrogen Inhibits Noradrenergic Function through ER Beta
  • Estrogen Receptor Beta Pharmacology in the Prostate
  • Estrogen Receptor Beta signal transduction pathway
  • Evaluating small molecules that potentiate anti-tumor immunity
  • Evaluating the Blood-Brain Barrier Bioavailability and in vivo Efficacy Potential of a Novel TAK1 Inhibitor Targeting Chronic Pain
  • Evaluating the efficacy of targeting the AGR2 axis in breast and prostate cancer
  • Evaluating the impact of KRas codon bias on pancreatic cancer
  • Evaluation of G1 antiestrogens in models of estrogen action
  • Evaluation of G1T38 and SERD XR5-28 in hormone refractory breast cancer
  • Evaluation of G1T48 in models of estrogen action
  • Evaluation of SGK as a therapeutic target in models of breast and prostate cancer
  • Evaluation of VT-464 in AR positive and ER positive breast cancer models
  • Evaluation of estrogen receptor as a therapeutic target in melanoma, lung and colorectal cancer models
  • Evaluation of kinase inhibitors
  • Evaluation of novel CDK4/6/9 inhibitors in triple negative breast cancer
  • Evaluation of the SERD XR5-28 in models of estrogen action
  • Evaluation of the therapeutic potential of combining VT464 and G1T38 in treatment-resistant prostate and breast cancer models
  • Examination Of Tgfb Induced Cell Death Pathway
  • Examining Biosynthesis and NAD+ Demand in the Warburg Effect
  • Examining infection-mediated metastasis with single-cell resolution
  • Excitatory Amino Acid Transmitters In Cns
  • Exosome LRRK2 in Predicting Parkinson Disease Phenotypes
  • Exploitation of a new targetable node in the AR signaling pathway in prostate cancer
  • Exploiting collateral sensitivity to target kinase inhibitor-resistant lung cancers
  • Exploiting metabolic vulnerabilities of CD4 T cell subsets to control inflammatory
  • Exploiting metabolic vulnerabilities of CD4 T cell subsets to control inflammatory disease
  • Exploiting targeted therapy-induced ATM dependence in residual lung tumors
  • Exploring BCL-XL addiction in pancreatic ductal adenocarcinoma
  • Exploring the role of polyploidy in tumor progression
  • Fellowship for Christina Dam
  • Fetal & Adolescent Nicotine Effects on CNS 5HT Systems
  • Functional and Mechanistic Dissection of GPCR Endosomal Signaling Dynamics
  • Functional optimization of CD8+ T cell metabolism for tumor control
  • Functional specialization of compartmentalized beta2-adrenergic signaling in neurons
  • G Protein Involvement in Oncogenesis and Metastasis
  • G(alpha)Z signaling in insulin secretion and glucose tolerance
  • GHB Tolerance and Dependence
  • Gender Differences In Stimulant Sensitization
  • Gender Differences In Stiumlant Sensitization
  • Gender Differences in Stimulant Action
  • Genes that modify Iron loading in mice
  • Genetic Disection Of Progesterone Receptor Function
  • Genetic Dissection of Progesterone Receptor Function
  • Genetic dissection of oncogenic RAS-driven tumor initiation in vivo
  • Genomic and Computational Approaches for Development of Novel Anticancer Therapies
  • Genomic and Functional Identification of Chemotherapy Resistance Mechanisms in Small Cell Lung Cancer
  • Glucose Transport in Regulation of T Cell Activation and Inflammation
  • Glucose metabolism and cell death in cancer
  • Glucose uptake and metabolism in lymphocyte fate and inflammatory bowel disease
  • Graduate Fellowship
  • Graduate Training In Pharmacological Research
  • Graduate Training In Pharmacological Sciences
  • Graduate Training Program in Pharmacological Sciences
  • Graduate Training Program in Pharmacological Sciences.
  • HDAC10, Mitochondria and autophagy-a novel network targeted by HDAC inhibitors
  • HOXB13 as a therapeutic target in prostate cancer
  • Heat Shock Transcription Factor Function and Regulation
  • High-throughput screening of arrayed single cells for automated analysis of phenotypic heterogeneity
  • Histone deacetylase 4 and neural activity-dependent muscle remodeling and atrophy
  • Hormonal regulation of a Ca2+/AMPK signaling pathway
  • Hypercholesterolemia as a modifier of the tumor microenvironment in breast cancer
  • Hypertrophy vs. Proliferation Following Tissue Injury: A Drosophila Model
  • IPA - David Walker
  • IPA - David Walker
  • IPA - Elisabetta Biasi
  • Identification and Characterization of Novel Cis-Regulatory Elements Controlling PTEN Expression
  • Identification of Chemokine Receptor Ligands with Novel Pharmacology
  • Identification of Novel Targets in Treatment Resistant Prostate Cancer
  • Identification of Therapeutic Interventions in Ataxia-Telangiectasia Using a Novel Model of Metabolic Stress
  • Identification of a novel target for treating breast cancer metastasis
  • Identification of actionable networks promoting breast cancer progression and brain metastasis
  • Identification of synthetic lethal interactors in pancreatic cancer
  • Identifying Objective Diagnostic Markers of Gulf War Illness: Salivary and Plasma Autoantibodies against Neural Proteins validated with Brain Imaging
  • Identifying gene-environment interactions that confer metabolic vulnerabilities in cancer
  • Identifying phosphatidylinositol metabolism vulnerabilities in cancer pathways
  • Identifying the molecular networks regulating cilium assembly and signaling
  • Improving the Oral Bioavailability and In vivo Efficacy of the TAK 1 Inhibitor, Takinib.
  • Improving the Oral Bioavailability and in vivo efficacy of the TAK 1 inhibitor, Takinib.
  • In Vitro Epileptogenesis And Seizure Expression
  • In vitro studies of perfluorinated chemicals
  • Inhibition of Cytochrome c-induced Caspase Activation
  • Innate and Adaptive Immunity in Parkinson Disease; Project 3: PD-linked Genetic Susceptibilities in Macrophage Responses
  • Institutional Summer Undergraduate Research Fellowship (SURF)
  • Integration Of Stress Response In Ontogeny--Role Of Crf
  • Integration Of Stress Response In Ontogeny: Role Of Crf
  • Integration of signaling and metabolic pathways in the regulation of EMT
  • Interaction of Galpha12 with cadherin in oncogenesis
  • Intercellular adhesion and morphogenesis: role of actin-regulatory proteins
  • Interrogating the RAS interactome for therapeutic vulnerabilities
  • Investigating and targeting metabolic vulnerabilities of MYC-driven small cell lung cancer
  • Investigating the Impact of ABL Kinase Signaling on Epigenetic Reprogramming in Metastatic Triple Negative Breast Cancer
  • Investigation Of A Cns L-Proline Transporter
  • Investigation of an ABL kinase-dependent signaling axis required for lung cancer brain metastasis
  • Iron homeostasis in mammalian muscle
  • Kinase Target of Diverse Cell Surface Receptors in Cancer Invasion and Metastasis
  • Leukemia Stem Cell Regeneration and Resistance
  • Leveraging copper chelation as targeted therapy for BRAF-driven thyroid cancer
  • Lineage-specific signaling and targeting of PI3K gamma in myeloid malignancies
  • Literature search of clinical trials studies on Hsp90 inhibitors
  • MECHANISMS OF CHLORPYRIFOS DEVELOPMENTAL NEUROTOXICITY
  • Manipulating normal estrogen physiology as a therapeutic approach in cancer
  • Mapping the landscape of drug sensitizers in human cancers
  • Maternal Cocaine & Neonatal Nervous System Development
  • Maternal Cocaine And Neonatal Nervous System Development
  • Mechanism Of Action Of Estrogens And Antiestrogens
  • Mechanism Of Pkc Regulation
  • Mechanism(s) of AR gene repression in prostate cancer
  • Mechanism-based targeting of unique survival signaling in residual tumors
  • Mechanism-informed combination strategies targeting metabolism in prostate cancer
  • Mechanisms and function of spatially encoded GPCR signaling
  • Mechanisms of Arginine Deprivation in Small Cell Lung Cancer
  • Mechanisms of LRRK2 Mediated Neurotoxicity
  • Mechanisms of Macrophage Evasion in Residual Melanoma
  • Mechanisms of TGF-B/Smad Signaling
  • Mechanisms of immune checkpoint resistance mediated by LKB1 tumor suppressor in lung cancer
  • Mechanisms of sarin neurobehavioral teratogenicity
  • Mediation Of T-Cell Development Of Cam Kinase Iv
  • Metabolic Control of T Cell Subsets and Pyruvate Dehydrogenase Kinase as a Target in Inflammatory Bowel Disease
  • Metabolic Regulation of 14-3-3zeta Acetylation in Breast Cancer
  • Metabolic Sensing and Stress Response Deficit in Ataxia Telangiectasia
  • Metabolism of Effector T cells as a Target in SLE
  • Metabolism of Effector T cells as a Target in SLE
  • Mining biology's extremes for new space radiation resistance strategies
  • Molecular And Cellular Mechanisms Underlying Dose-Response
  • Molecular And Cellular Mechanisms Underlying Dose-Response
  • Molecular Basis Of Signaling By The Cab1 Proto-Oncogene
  • Molecular Basis Of Signaling By The Cabl Proto-Oncogene
  • Molecular Basis of Signaling by the cAbl Proto-Oncogene
  • Molecular Control of Cardiomyocyte Mitophagy by the RhoGAP GRAF1
  • Molecular Determinants of Androgen Receptor Pharmacology
  • Molecular Mechanism of activation and gating in the NMDA receptor
  • Molecular Mechanisms Of Protein Prenylation
  • Molecular Mechanisms Of Protein Prenylation
  • Molecular Pharmacology And Physiology Of Nicotine
  • Molecular determinants underlying herceptin sensitivity and resistance
  • Molecular mechanisms of chemoresistance in breast cancer
  • Molecular mechansim of novel androgen receptor agonists
  • Molecular pharmacology of bazedoxifene and pipendoxifene in breast cancer
  • NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanoma
  • NMDA Receptor-- Agonist Affinity, Efficacy/Transduction
  • Nanobodies for the detection of CCR2 activation
  • Neuronal And Hormonal Factors In Normal And Abnormal
  • Neuronal And Hormonal Factors In Normal And Abnormal Kidne
  • New Animal Model For Early Onset Nonimmune Diabetes
  • New Approaches to Cardiothoracic Tolerance Induction
  • Non-Canonical Responses to DNA damage in Drosophila Polyploid Cells
  • Non-canonical roles for ATM kinase in regulating mitochondrial function and redox homeostasis
  • Nonclassical signaling of the androgen receptor polyproline domain
  • Novel Approaches to Resolve Functional Specificity in the Chemokine System
  • Novel Combinatorial Screening for NTFs, NPCs, MMPs, and CCs in relevance to Autoantibodies in the Serum and CSF of Veterans with GWI
  • Novel auto antibody serum and cerebrospinal fluid Biomarkers in veterans with Gulf War Illness
  • Novel druggable pathway required for lung cancer progression and metastasis
  • Novel target for therapy refractory lung tumors
  • Nutrition And Adrenergic Receptor Mechanisms In Ontog
  • Nutrition And Adrenergic Receptor Mechanisms In Ontog
  • Opiate Effects On Maturation Of Endocrine Regluation
  • Opiate Effects On Maturation Of Endocrine Regulation
  • Opioid Effects On Maturation Of Endocrine Regulation
  • Optimization of ERalpa-LBD-based CAR-T switch
  • PPARgamma-cofactor interactions in fibrotic liver
  • PROMINENT - DUKE
  • PROMINENT - Discovering the molecular signatures of cancer PROMotion to INform prevENTion
  • Par-4 Regulation and Function in Breast Cancer Dormancy and Recurrence
  • Pathways regulating dormant cell survival and recurrence
  • Peptide Antagonists of the Glucocorticoid Receptor
  • Pharmacokinetics and efficacy of SNX-5422 in suppressing SARS-CoV-2 viral loads in Golden Syrian Year 1 Hamsters
  • Pharmacologic reversal of behavioral teratogenesis: pilot study
  • Pharmacological Sciences Training Grant
  • Pharmacological Sciences Training Program
  • Pharmacological targeting of estrogen receptor to enhance melanoma immunity
  • Pharmacology Industry Internships for Ph.D. Students
  • Phosphatase Inhibitor 1, An Amplifier of cAMP Signals
  • Phosphatase Inhibitor-1, An Amplifier Of Camp Signals
  • Pleiotrophin, a paracrine regulator of hematopoietic stem cell fate
  • Polyploidy after tissue injury: a Drosophila model
  • Polyploidy in Cardiac Development and Tissue Repair in Drosophila
  • Precision targeting of altered mitochondrial states in ovarian cancer
  • Preclinical Development Of Novel Borrelia Sp. Targeting Therapeutic And Diagnostic Imaging Agents.
  • Preclinical Evaluation of PK2 Antagonists for Pancreatic Cancer
  • Preclinical evaluation of NOS inhibitors for the treatment of pancreatic cancer
  • Profiling Gene Interactions in the Human Kinome
  • Protein Phosphatase 1 Regulation by Multiple Subunits
  • Protein Phosphatase-1 - Targeting the Cytoskeleton
  • Proteome Mining as a Predictive Tool of Drug Toxicity
  • RIP140 as a mediator of Estrogen Receptor action in tumor associated macrophages
  • Rad17- & p53-mediated apoptotic pathways in response to DNA damage
  • RalA signal transduction
  • Reaper Mediated Apoptosis
  • Reaper-Scythe Regulated Apoptosis
  • Reducing dietary copper for the treatment of BRaf mutation-positive melanoma
  • Regulating and harnessing immunity with junk DNA
  • Regulation Of Cyclic Gmp Phosphodiesterase By Gz
  • Regulation Of G Protein Mediated Signaling
  • Regulation Of The Caba Receptor-Chloride Ion Channel
  • Regulation Of The Gaba Receptor-Chloride Ion Channel
  • Regulation of Apoptosis
  • Regulation of G-Protein Signaling
  • Regulation of Iron Homeostasis
  • Regulation of LRRK2 in lysosomal stress response
  • Regulation of M phase exit
  • Regulation of REDD1 and caspase-2 by FASN inhibition in ovarian cancer
  • Regulation of Rho Signaling by S-Nitrosothiols
  • Regulation of cell permeability by Abl kinases and implications for the treating of acute lung injury
  • Regulation of smooth muscle-myosin phosphatase 1 kinase
  • Regulation of the retinal ganglion cell repair program by the mitochondrial protein Armcx1
  • Regulation, function, and impact of developmental retrotransposon activation
  • Regulatory principles of the Warburg Effect
  • Role Of Ornithine Decarboxylase And Polyamines In Kidney
  • Role of Abl Kinases in immune cell signaling
  • Role of Chloride Transporters in Cerebral Ischemia
  • Role of ER RNA Binding Domain in Breast Cancer
  • Role of G(alpha)Z in Pancreatic Islet Beta-cell Biology
  • Role of Rab10 in Alzheimer's disease
  • Role of Tyrosine Kinases & Adaptor Proteins in Migration
  • Roles of mitochondrial dynamics and mtDNA in senescence
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  • Science Education in Health Ed Class: Tobacco and Addiction
  • Screening for ATM/DNA-PK inhibitors
  • Selectively targeting apoptosis in PIK3CA mutant colorectal cancers
  • Serotonergic Contribution to Adolescent Risk Taking
  • Shared Instrumentation For Anatomical Studies
  • Shared Instrumentation For Confocal Ion Imaging In Living
  • Signal Amplification by an RTK/Abl Kinase Module
  • Single cell functional dissection of tumor microenviornment-driven drug resistance
  • Single-Molecule Array Measurements of LRRK2 and pRab10 in Biofluids
  • Small molecular weight eNOS inhibitors for the treatment of pancreatic cancer
  • Somatic transposition-mediated genome variegation during development, disease and aging conditions
  • Sructural Basis Of Ion Channel Opening
  • Stem Cells, Progenitors, and the Origin of Medulloblastoma
  • Strategies to overcome immunotherapy resistance in LKB1 and KEAP/NRF2 mutated NSCLC: modulating ferroptosis to restore immune sensitivity
  • Structural Basis Of Ion Channel Opening
  • Structure Function Of Genetic Engineered Calmodulins
  • Structure and Function of ICMT Methyltransferase
  • Structure/Function Of Genetic Engineered Calmodulins
  • Studying the impact of aberrant beta(2)-adrenergic receptor trafficking on endosomal signaling and cellular responses
  • Synthetic lethality by targeting the core senescent mechanism in lung cancer.
  • Systematic design of CDK4/6 inhibitor-based combination therapies
  • Systematic dissection of the breast cancer microenvironment using the MicroSCALE Toolkit
  • T cell metabolism as a determinant of differentiation in allergic asthma
  • TGF-Beta Signaling in MSCs and Osteoblast
  • TGFBI and tumorigenesis
  • TRACEABLE-MAP: targetable reactive metabolites for metabolomic profiling
  • Targeting ABL kinases to regulate epithelial cell plasticity and regeneration following injury
  • Targeting Borrelia specific immune cell populations in vivo through expression of ectopically expressed Hsp90
  • Targeting Functional Domains in Telomerase
  • Targeting Integrator Kinases in Lung Cancer Metastasis
  • Targeting SCLC plasticity with constellation pharmacology
  • Targeting UHRF1 in combinational immunotherapy
  • Targeting aerobic glycolysis in T-ALL
  • Targeting differential apoptosis regulation in triple negative breast cancer
  • Targeting heat shock protein 72 to improve renal function after transplantation
  • Targeting the CDK 4/6 axis in Castration Resistant Prostate Cancer
  • Targeting the GRHL2/AGR2/LYPD3 axis in breast cancer
  • Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis
  • Targeting tumor-specific apoptosis regulation in advanced ER+ breast cancer
  • Targeting undruggable oncogenes through the epigenome
  • Tgf-B Signaling Pathway And Cell Growth Regulation
  • Tgf-Beta Signaling Pathway And Cell Growth Regulation
  • The Alcohol Pharmacology Education Partnership
  • The Androgen Receptor: Cofactor Interface
  • The Biology of Inositol Polyphosphate Signaling
  • The Molecular Basis of Affinity and Efficacy in the N-methyl-D-aspartate Receptor
  • The Molecular Basis of Ion Channel Opening
  • The Molecular Basis of Telomerase Function & Regulation
  • The Pharmacology Education Partnership
  • The Role Of Tumor Supressor Smads In Tgf-B Signaling
  • The Role of Abl Kinase Signaling in HER2+ Breast Cancer Brain Metastasis
  • The Role of Epigenetic Plasticity in Breast Cancer Recurrence
  • The Role of USP22 in Prostate Cancer Development and Progression
  • The Roles of MicroRNAs in Glioblastoma
  • The Structural Basis Of Ion Channel Opening
  • The Stuctural Basis Of Ion Channel Opening
  • The Systematic Identification and Analysis of Replication Origins in Drosophila
  • The anti-senescence activity of trefoil factor 1
  • The effect of oncogenic Ras signaling strength on cancer
  • The pharmacological actions of antiprogestins in uterine fibroids
  • The role of ATM in Metabolic Stress Responses
  • The role of CaMKK2 in tumor-infiltrating natural killer cells
  • The role of ERRalpha/PGC-1 in disease pathogenesis
  • The role of KRAS codon bias in tumorigenesis
  • The role of NRF2 in breast cancer dormancy and recurrence
  • The role of RNA-binding protein Lin28a in hypertrophic cardiomyopathy
  • The role of TGF-beta in tumorigenesis
  • The role of dietary copper in melanoma
  • Transient Cerbral Ischemia & Gaba Neurotransmission
  • Transient Cerebral Ischemia & Gaba Neurotransmission
  • Transient Cerebral Ischemia & Gaba Neurotransmission
  • Transient Cerebral Ischemia And Gaba Neurotransmission
  • Transient Global Ischemia & Inhibitory Neurotransmission
  • Translational Regulation of Glutamate Receptors
  • Trophic Regulation in T Cell Homeostasis and Disease
  • Uncovering a novel role for primary cilia in Eph/Ephrin signaling in neurons
  • Uncovering actionable signaling pathways required for solid tumor brain metastasis
  • Uncovering actionable signaling pathways required for solid tumor brain metastasis
  • Undergraduate enrichment experiences to support biomedical careers: An investigation of underlying psychological mechanisms
  • Understanding and targeting RNA/transcription-dependent DNA repair in cancer cells
  • Understanding metabolic flux and the control of mammalian cell growth
  • Understanding metabolic vulnerabilities in cancer and the impact the tumor microenvironment has on cancer progression
  • Understanding methionine metabolism and its therapeutic potential in cancer
  • Understanding the impact that tumor representative oxygen tension has on phosphotyrosine-dependent signaling networks in solid tumors
  • Unmasking targetable dependencies in cancer with intrinsic or acquired resistance to anti-cancer therapies
  • Urate-LLRK2 interactions in Parkinson's disease
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