Molecular Genetics and Microbiology

• 

  People

  • Administrative Positions

    • Cullen, Bryan R., Director, Center for Virology
    • Garcia-Blanco, Mariano Agustin, Director, Center for RNA Biology
    • Heitman, Joseph, Chair, Department of Molecular Genetics and Microbiology
    • Jinks-Robertson, Sue, Vice-Chair in the Department of Molecular Genetics and Microbiology
    • Luftig, Micah Alan, Vice-Chair in the Department of Molecular Genetics and Microbiology
    • Marchuk, Douglas Alan, Director, Center for Experimental Genetics
    • Marchuk, Douglas Alan, Director, Duke University Program in Genetics and Genomics

  • Professorships

    • Cullen, Bryan R., James B. Duke Professor of Molecular Genetics and Microbiology
    • Heitman, Joseph, James B. Duke Professor of Molecular Genetics and Microbiology
    • Joklik, Wolfgang Karl, James B. Duke Professor Emeritus of Medicine
    • Keene, Jack Donald, James B. Duke Professor of Molecular Genetics and Microbiology
    • Marchuk, Douglas Alan, James B. Duke Professor of Molecular Genetics and Microbiology
    • Petes, Thomas Douglas, Minnie Geller Professor of Research in Genetics, in the School of Medicine

  • Primary Appointments

    • Abaffy, Tatjana, Assistant Research Professor in Molecular Genetics and Microbiology
    • Bastidas, Robert J, Assistant Research Professor in Molecular Genetics and Microbiology
    • Chi, Jen-Tsan Ashley, Associate Professor in Molecular Genetics and Microbiology
    • Cirulli, Elizabeth, Adjunct Assistant Prof in the Department of Molecular Genetics and Microbiology
    • Coers, Jorn, Associate Professor in Molecular Genetics and Microbiology
    • Cullen, Bryan R., Professor of Molecular Genetics and Microbiology
    • David, Lawrence Anthony, Assistant Professor of Molecular Genetics and Microbiology
    • Dietrich, Fred Samuel, Associate Professor of Molecular Genetics and Microbiology
    • Dressman, Holly Kloos, Research Professor in Molecular Genetics and Microbiology
    • Garcia-Blanco, Mariano Agustin, Adjunct Professor in the Molecular Genetics and Microbiology
    • Harrell, Lizzie Johnson, Research Professor Emeritus of Molecular Genetics and Microbiology
    • Heaton, Brook, Assistant Research Professor of Molecular Genetics and Microbiology
    • Heaton, Nicholas Scott, Assistant Professor of Molecular Genetics and Microbiology
    • Heitman, Joseph, Professor of Molecular Genetics and Microbiology
    • Horner, Stacy M., Assistant Professor of Molecular Genetics and Microbiology
    • Jinks-Robertson, Sue, Professor of Molecular Genetics and Microbiology
    • Joklik, Wolfgang Karl, Professor Emeritus of Molecular Genetics and Microbiology
    • Keene, Jack Donald, Professor of Molecular Genetics and Microbiology
    • Kim, So Young, Assistant Research Professor in Molecular Genetics and Microbiology
    • Ko, Dennis, Assistant Professor in Molecular Genetics and Microbiology
    • Kokoska, Robert J, Adjunct Professor in the Department of Molecular Genetics and Microbiology
    • Lee, Sunhee, Adjunct Associate Professor in the Department of Molecular Genetics and Microbiology
    • Linney, Elwood Albert, Professor Emeritus of Molecular Genetics and Microbiology
    • Lowe, Craig, Assistant Professor of Molecular Genetics and Microbiology
    • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology
    • Marchuk, Douglas Alan, Professor of Molecular Genetics and Microbiology
    • Matsunami, Hiroaki, Professor of Molecular Genetics and Microbiology
    • McCusker, John Henry, Associate Professor of Molecular Genetics and Microbiology
    • Mieczkowski, Piotr Andrzej, Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
    • Mitchell, Thomas Greenfield, Associate Professor Emeritus in Molecular Genetics and Microbiology
    • Petes, Thomas Douglas, Professor of Molecular Genetics and Microbiology
    • Pickup, David James, Associate Professor Emeritus of Molecular Genetics and Microbiology
    • Rawls, John Franklin, Associate Professor of Molecular Genetics and Microbiology
    • Scaglione, Matt, Assistant Professor of Molecular Genetics and Microbiology
    • Scott, Kristin Caruana, Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
    • Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology
    • Sullivan, Beth Ann, Associate Professor of Molecular Genetics and Microbiology
    • Sun, Sheng, Assistant Research Professor in Molecular Genetics and Microbiology
    • Tobin, David M., Associate Professor of Molecular Genetics and Microbiology
    • Valdivia, Raphael H., Professor of Molecular Genetics and Microbiology
    • Wheat, Robert W., Professor Emeritus of Molecular Genetics and Microbiology
    • Yan, Dong, Assistant Professor of Molecular Genetics and Microbiology

  • Secondary Appointments

    • Abraham, Soman Ninan, Professor in Molecular Genetics and Microbiology
    • Alspaugh II, James Andrew, Professor in Molecular Genetics and Microbiology
    • Ashley-Koch, Allison Elizabeth, Research Professor in Molecular Genetics and Microbiology
    • Asokan, Aravind, Professor of Molecular Genetics and Microbiology
    • Crawford, Gregory E., Associate Professor in Molecular Genetics and Microbiology
    • Derbyshire, Emily R., Assistant Professor in Molecular Genetics and Microbiology
    • Diehl, Anna Mae, Professor in Molecular Genetics and Microbiology
    • Ferrari, Guido, Associate Research Professor in Molecular Genetics and Microbiology
    • Fouda, Genevieve Giny, Assistant Research Professor in the Department of Molecular Genetics and Microbiology
    • Fowler Jr., Vance Garrison, Professor in Molecular Genetics and Microbiology
    • Frothingham, Richard, Assistant Professor in Molecular Genetics and Microbiology
    • Gordan, Raluca Mihaela, Assistant Professor in Molecular Genetics and Microbiology
    • Gregory, Simon Gray, Research Professor in Molecular Genetics and Microbiology
    • Gromeier, Matthias, Professor in Molecular Genetics and Microbiology
    • Hammer, Gianna, Assistant Professor in Molecular Genetics and Microbiology
    • Hauser, Michael Arthur, Associate Research Professor in Molecular Genetics and Microbiology
    • Holley, Christopher Lee, Assistant Research Professor of Molecular Genetics and Microbiology
    • Jiang, Yong-Hui, Professor in the Department of Molecular Genetics and Microbiology
    • Kishnani, Priya Sunil, Professor in the Department of Molecular Genetics and Microbiology
    • Klotman, Mary E, Professor in Molecular Genetics and Microbiology
    • Koeberl, Dwight D., Professor in Molecular Genetics and Microbiology
    • Kuehn, Margarethe Joanna, Associate Professor in Molecular Genetics and Microbiology
    • Le, Thuy, Associate Professor of Molecular Genetics and Microbiology
    • Lew, Daniel Julio, Professor in Molecular Genetics and Microbiology
    • MacLeod, Amanda S, Assistant Professor of Molecular Genetics and Microbiology
    • Magwene, Paul Mitaari, Associate Professor in Molecular Genetics and Microbiology
    • Nyunt, Myaing M., Associate Professor in the Department of Molecular Genetics and Microbiology
    • Perfect, John Robert, Professor in Molecular Genetics and Microbiology
    • Permar, Sallie Robey, Professor of Molecular Genetics and Microbiology
    • Plowe, Christopher Vine, Professor in the Department of Molecular Genetics and Microbiology
    • Reddy, Timothy E, Associate Professor in Molecular Genetics and Microbiology
    • Rockman, Howard Allan, Professor in Molecular Genetics and Microbiology
    • Saunders, Kevin O'Neil, Assistant Professor in the Department of Molecular Genetics and Microbiology
    • Shen, Xiling, Associate Professor in Molecular Genetics and Microbiology
    • Sherwood, Nina Tang, Assistant Research Professor in Molecular Genetics and Microbiology
    • Shinohara, Mari L., Associate Professor in Molecular Genetics and Microbiology
    • Steinbach, William J., Professor in Molecular Genetics and Microbiology
    • Sullenger, Bruce Alan, Associate Professor in Molecular Genetics and Microbiology
    • Surana, Neeraj K, Assistant Professor in the Department of Molecular Genetics and Microbiology
    • Taylor, Gregory Alan, Associate Research Professor in Molecular Genetics and Microbiology
    • Thiele, Dennis James, Professor of Molecular Genetics and Microbiology
    • Tomaras, Georgia Doris, Professor in Molecular Genetics and Microbiology
    • Tsalik, Ephraim, Associate Professor in the Department of Molecular Genetics and Microbiology
    • Vilgalys, Rytas J., Assistant Professor in Molecular Genetics and Microbiology
    • You, Lingchong, Associate Professor in Molecular Genetics and Microbiology
    • Zhuang, Yuan, Professor of Molecular Genetics and Microbiology

  • Non-Faculty Positions

    • Moreno, Angelo, Research Scholar
    • Wang, Liuyang, Research Scientist

  • Students

    • Allison, Jonathan, Student
    • Antonia, Alex, Student
    • Arnson, Benjamin, Student
    • Barnes, Alyson, Student
    • Bethke, Jonathan, Student
    • Cable, Jana, Student
    • Chang, Zanetta, Student
    • Choe, Ha, Student
    • D'Arcy, Brooke, Student
    • Darryl Irwan, Ishak, Student
    • Detter, Matthew, Student
    • Dumm, Rebekah, Student
    • Esoda, Caitlin, Student
    • Espenschied, Ted, Student
    • Gibbs, Kyle, Student
    • Gokhale, Nandan, Student
    • Gonzalez, Trevor, Student
    • Guo, Weilun, Student
    • Hamele, Cait, Student
    • Harding, Alfred, Student
    • Hu, Xiaoyang Serene, Student
    • Hughes, Kelly, Student
    • Iskarpatyoti, Jason, Student
    • Jawahar, Jay, Student
    • Jenks, Jennifer, Student
    • Letourneau, Jeffrey, Student
    • Lu, Kuan-Yi, Student
    • Lupan, Bianca, Student
    • McMillan, Hannah, Student
    • Messinger, Joshua, Student
    • Mitchell-Dick, Aaron, Student
    • Moore, Makala, Student
    • Mosaheb, Mubeen, Student
    • Nohara, Junsuke, Student
    • Padilla Mercado, Gilberto, Student
    • Palmucci, Julia, Student
    • Passer, Andrew, Student
    • Priest, Shelby, Student
    • Ramirez, Zeni, Student
    • Roundtree, Mark, Student
    • Smith, Timothy, Student
    • Snellings, Daniel, Student
    • Snider, Daltry, Student
    • Stanland, Lyla, Student
    • Stantial, Nicole, Student
    • Sun, Alice, Student
    • Sylvester, Kayla, Student
    • Tan, Chin Yee, Student
    • Trimarco, Joe, Student
    • Vazquez, Christine, Student
    • Willard, Katie, Student
    • Xu, Yitong, Student
    • Zhang, Albert, Student
    • Zhu, Kevin, Student
• 

  Administers Grant

  • 13661osome Movement In Meiosis And Mitosis
  • A Combination Therapy Approach to Treating Drug Resistant Fungal Infections
  • A Computer Modeling Approach to Create an Antifungal to Improve the Treatment of Cryptococcal Infections
  • A Computer Modeling Approach to Create an Antifungal to Improve the Treatment of Cryptococcal Infections
  • A Genomics Approach to Study C. neoformans var. grubii
  • A Mouse Model of Cerebral Cavernous Malformations
  • A Novel Integrative Pathway Regulating Intestinal Glucose Sensing
  • A Persistent Rna-Dna Hybrid At A T4 Replication Origin
  • A Structural Approach for Treating Drug Resistant Fungal Pathogens
  • A comprehensive research resource to define mechanisms underlying microbial regulation of host metabolism in pediatric obesity and obesity-targeted therapeutics
  • A high througput platform for screening microbial interactions
  • A role for pathogen-induced IL-10 production in susceptibility to MS
  • AN ATLAS OF SHARED GENETIC ARCHITECTURE CONNECTING CELL BIOLOGY AND HUMAN DISEASE
  • ANALYSIS OF GENETICALLY & ENVIRONMENTALLY OVERLAPPING YEAST QUANTITATIVE TRAITS
  • ATTRACT: Arterial flow as attractor for endothelial cell migration - a new concept in vascular malformation and stroke regeneration
  • Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transporters
  • Alfred P. Sloan Research Fellowship for Dr. Lawrence David in Computational & Evolutionary Molecular Biology
  • Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors
  • Amelioration of neural stem cell defects underlying Zika virus induced microcephaly
  • An RNA-targeted platform for anti-flavivirus drug discovery
  • Analysis of a novel class of molecular chaperones that suppress polyglutamine aggregation
  • Analysis of the Exon Junction Complex in Neural Development and Microcephaly
  • Antigenically stabilized H3N2 vaccines that avoid egg adaption
  • Antitumor Agents And The Bacteriophage T4 Topoisomerase
  • BRAIN EAGER: Solving the Code of Olfaction Using Nano-Robot Switchable Odorants
  • BWF Ad Hoc grant Request ID# 1018498
  • Basic Mechanisms In Infectious Diseases
  • Basic Mechanisms In Infectious Diseases
  • Biochemical and functional investigation of the novel enzymatic activities of MESH1
  • Biogenesis of olfactory G protein-coupled receptors
  • Boosting innate immunity against Yersinia pestis
  • Brain Vasular Malformation Consortium: Predictors of clinical course
  • Building archaic hominin olfactory receptors: a functional approach to paleogenomes
  • C. elegans to study organismal control of recovery from bacterial infections
  • Causes and Consequences of Hypermutability in Cryptococcus neoformans
  • Cell Type-Specific Viral Translation in the CNS
  • Cellular Coactivators of the HIV 1 Promoter
  • Characterization of Chromosome Fragile Sites in Yeast
  • Characterization of a novel Salmonella regulator of IL-10 production and its role in pathogenesis
  • Chlamydia Effector Proteins
  • Chlamydia co-option of Eukaryotic Lipid Droplets
  • Chromosome Movement In Meiosis And Mitosis
  • Collaborative Research: Analysis of the Mammalian Olfactory Code
  • Comparison of oxidant damage, Nrf2 characteristics, and gene modification of cord blood versus plerixafor-mobilized adult CD34+ cells from sickle cell disease patients
  • Compound library reformatting
  • Connections between mRNA elongation and splicing
  • Control of cell fate by progenitor mitosis length and microcephaly-linked genes during cortical development
  • Core A: Animal Models Core 2. Duke University Zebrafish Facility
  • Defining a novel function for the post-translational modification ufmylation in the antiviral innate immune response
  • Defining how a tyrosine within the hepatitis c virus protease regulates antiviral innate immunity
  • Defining novel Riplet-activated antiviral innate immune signaling pathways
  • Defining the Mechanism of ubiquitin transfer by Ube2k
  • Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycle
  • Detect autologous transfusion by novel separation and characterization of RBC storage exosomes
  • Detecting autologous blood doping through the analysis of erythrocyte transcriptome
  • Determinants Of Specificity In Protein-Rna Interactions
  • Development of BA-1049 for treatment of cerebral cavernous malformations
  • Developmental Regulation Of The Glucocortocoid Response
  • Dicentric chromosome formation and stability in humans
  • Discovering natural bacterial interactions within the human gut microbiota
  • Discovering novel antifungal agents via multi-species profiling of a structurally and stereochemically diverse, well-validated compound library
  • Discovery and development of broad spectrum anti-flaviviral drugs
  • Disruption of latent HIV-1 proviruses using CRISPR/Cas endonucleases
  • Dissecting the role of the exon junction complex in embryonic corticogenesis
  • Distal mRNA localization and translation in neural stem cells of the developing brain
  • Duke/NIDDK Functional Genomics Center
  • Edities Of Cryptococcus Neoformans Associated With Aids
  • Effect of APOBEC3G on retroviruses and retrotransposons
  • Effect of m6A editing of RNA on influenza A virus replication
  • Effect of m6A methylation of HIV-1 transcripts on viral replication
  • Embryonal Carcinoma Growth And Differentiation
  • Embryonal Carcinoma Growth And Regulation
  • Environmental and genetic regulation of copy number variation (CNV)
  • Epigenetic Determinants of Centromere Function and Stability in Human Dicentric Chromosomes
  • Epitranscriptomic Control of Local Gene Expression in Neural Stem Cells
  • Epitranscriptomic modification of HIV-1 transcripts: Effects of drugs of abuse
  • Examination Of The Estrogen Response Pathways In A New Ver
  • Forward and Reverse Genetics in Chlamydia
  • Funcional characterization of early Chlamydia effectors
  • Function of Mammalian ELAV RNA-Binding Proteins
  • Function of alpha herpesvirus microRNAs
  • Function of nucleic acid binding DENV host factors
  • Function of the Rapamycin Targets: The TOR Kinases
  • Functional Characterization of the GNAQ somatic mutation causing Sturge Weber syndrome
  • Functional Genomic Analysis of the Chlamydia Inclusion
  • Functional Genomic Screens of Tumor Recurrence in Ovarian Cancer
  • Functional genomics of human variation to Salmonella invasion
  • Fungal-specific drug targets: static vs. cidal starvation & toxic intermediates
  • GPCR signaling cascades in Cryptococcus neoformans
  • Gene Discovery for Cerebral Cavernous Malformations
  • Gene expression Profiling in Mammalian Taste Tissue
  • Gene expression programs of lactic acidosis in human cancers
  • Generation of genomic duplications and deletions in yeast
  • Genesis and Progression of Cerebral Cavernous Malformations
  • Genetic Analysis in Chlamydia
  • Genetic Diversity and Complex Traits in S Cerevisiae
  • Genetic Mechanisms Affecting Gene Copy Number
  • Genetic Mechanisms Affecting Gene Copy Number And
  • Genetic analysis in an intractable gut microbe
  • Genetic analysis of Cryptococcus neoformans virulence
  • Genetic analysis of a beneficial gut bacterium
  • Genetic analysis of innate immunity using C. elegans
  • Genetic analysis of mucin utilization by Akkermansia muciniphila and its impact on host physiology
  • Genetic dissection of angiogenesis in the tuberculous granuloma
  • Genetic elements of cancer cell survival in tumor microenvironment stresses
  • Genetic regulation of genome stability in yeast
  • Genetic regulation of genome stability in yeast
  • Genetic regulation of genome stability in yeast
  • Genetic study of gap junction formation and regulation in C. elegans neurons
  • Genetically stable Picornavirus HIV Immunization vectors
  • Genetics of Cryptococcus sexual reproduction
  • Genetics of Hereditary Hemorrhagic Telangiectasia
  • Genomic Analysis of Centromere Assembly and Function
  • Genomic and Epigenetic Mechanisms of Human Centromere Assembly and Chromosome Stability
  • HOST GENETIC VARIATION REGULATING SALMONELLA INVASION AND DISEASE SUSCEPTIBILITY
  • Hemagglutinin proteins with non-immunogenic head domains as a universal influenza virus vaccine
  • High throughput S. cerevisiae HAM, GWA & QT/QTL architecture
  • High-throughput mapping of olfactory receptor identity to olfactory bulb glomeruli
  • Host Innate Immune-Microbial Interactions in Intestinal Inflammation
  • Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation
  • Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation
  • Host-mediated lysis of cytoplasmic pathogens
  • Host-pathogen interactions in hepatitis C virus replication
  • Human GBPs in cell-autonomous immunity to intracellular bacterial pathogens
  • Human Genetic Variance and Cellular Responses to Sexually Transmitted Infections
  • Human Stringent Response as Novel Therapeutic Approaches for Breast Cancers
  • Identification of Coxiella burnetti Effector Proteins
  • Identification of Modifier Genes in Heart Disease
  • Identification of genetics modifiers of heart disease
  • Identifying genes required for digestive physiology and lipid metabolism
  • Identifying the CCM3 Gene: Understanding Familial Stroke
  • Imaging Alternative Splicing During Tumor Progression
  • Immune Compromised Zebrafish for Cell Transplantation
  • Implications of 14-3-3 in topoisomerase II pharmacology
  • Improvement of genetic analysis in the pathogenic zygomycete Mucor circinelloides
  • In vivo patterns of receptor activation by odorants
  • Influenza virus small RNAs
  • Initiation Of Dna Replication In The Phage T4 System
  • Initiation Of Dna Replication In The Phage T4 Systems
  • Initiation Of T4 Replication: Study Of An Rna-Dna Hybrid
  • Initiation of T4 Replication - Study of an RNA/DNA Hybrid
  • Innate Immune Regulation during hepatitis C virus infection
  • Innate immune recognition of bacterial secretion systems by GBPs
  • Integrated instrument systems for maintenance and delivery of RNAi libraries
  • Interferon stimulated genes that regulate viral infection by binding to modified RNAs
  • Interferon-driven ubiquitin response targets Chlamydia inclusions in human cells
  • Interferon-inducible cell-intrinsic host defense against Chlamydia trachomatis
  • Introducing Genetic Material Into Stem Cells
  • Investigating post-translational regulation of innate immunity in C. elegans
  • Investigating the Molecular Pathways of Cerebral Cavernous Malformation Maturation
  • Investigating the Type II Secretion System of Chlamydia trachomatis
  • Investigating the function of the Mcgl Family
  • Investigating the origin of spontaneous mitotic homologous recombination in Saccharomyces cerevisiae
  • Investigation into protein quality control pathways in Dictyostetlium discoideum
  • Investigation into protein quality control pathways in Dictyostetlium discoideum
  • Investigation of the two-hit hypothesis for Cerebral Cavernous Malformations
  • IsoCyte Laser Scanning Plate Cytometer for High-throughput, High-content Assays
  • Iterative Cloning A Novel Approach To Quantitative Genetic
  • Linking oxygen and bacterial ecology in necrotizing enterocolitis
  • Loss of cellular identity after influenza virus infection and effects on pulmonary function
  • Loss of cellular identity after influenza virus infection and effects on pulmonary function
  • Macromolecular Synthesis In Virus-Infected Cells
  • Macromolecular Synthesis In Virus-Infected Cells
  • Macromolecular Synthesis Of Virus-Infected Cells
  • Macrophage Reprogramming During Granuloma Formation in the Zebrafish
  • Mapping the RNA modification N6-methyladenosine during Zika virus infection
  • Mechanisms of Centromere Function
  • Mechanisms of Human Chromosome Rearrangement and Stability
  • Mechanisms of RAB1B regulation of antiviral innate immune signaling
  • Mechanisms of methylthioadenosine signaling during Salmonella infection
  • Mechanisms of neural circuit formation in C. elegans
  • Mechanisms of neural progenitor division in the developing brain
  • Metabolic regulation of KLHL proteins through O-glycosylation
  • Microbial Ecology of the Zebrafish Intestine
  • Microbial Regulation of Nuclear Receptor Activity in the Intestinal Epithelium
  • Microbial and inflammatory regulation of intestinal epithelial gene transcription
  • Microbial regulation of host nutrient metabolism
  • Microfluidic PCR Platform to Detect Microbial DNA
  • Mitochondrial DNA Stability and Mutagenesis
  • Modulating Eicosanoids to Treat Tuberculosis: Personalized, Host-directed Therapy
  • Modulation of Host Cell Environment by Mycobacterial PE/PPE Proteins
  • Modulation of Odorant Receptor Function
  • Molecular Biology Of The Ro-Rnp Autoantigen
  • Molecular Identification of Pathogenic Fungi
  • Molecular Mechanism of HIV-1 Vif Function
  • Molecular Mechanisms Underlying Odorant Recognition
  • Molecular Mechanisms Underlying Specific Anosmia and Sensitization
  • Molecular Mycology and Pathogenesis Training Program
  • Molecular Targeting of Breast Cancer
  • NSF sponsored conference
  • Natural genetic variation regulating infarct volume
  • Novel Antifungal Therapeutic Approaches
  • Novel Recombinant Streptococcus mitis as an oral vaccine against HIV/AIDS
  • Novel Regulatory Controls of Hepatitis C Virus Envelopment and Secretion by the Viral NS4A Protein
  • Novel Targets for Stroke Intervention - Gene Discovery for Modulators of Infarction
  • Novel chaperones and neurodegeneration
  • Novel methods of generating genetic diversity
  • Nuclear, mitochondrial and L-A virus contributions to yeast quantitative traits
  • Olfactory moding in mammals
  • Oncogenic Gene Regulatory Networks
  • Organization and Regulation of Eukaryotic Centromeres
  • Organization and Stability of Centromeric Chromatin
  • Organotin influences on assembly and obesogenic activity of the gut microbiota
  • Pathogenesis of vascular malformations in hereditary hemorrhagic telangiectasia: from disease mechanism to new therapies
  • Peripheral Odor Coding in Mammals
  • Personalizing prebiotic therapies for astronauts' gut microbiota
  • Personalizing prebiotic therapies that target human gut microbiota
  • Personalizing prebiotic treatments that manipulate human gut microbiota
  • Phase I enzymes as part of an epigenetic switch
  • Phase Variation in Saccharomyces cerevisiae
  • Post-transcriptional RNA regulation in mammalian neural stem cells
  • Post-transcriptional coordination by HuR and microRNAs during tumorigenesis
  • Posttranscriptional Gene Regulation in T Cell Activation
  • Posttranscriptional regulation of the Wnt pathway by HuR and microRNAs
  • Posttranslational modifications of host proteins by Chlamydia effectors
  • Predicting prebiotic effects on human microbiota, behavior, and cognition.
  • Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors
  • Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors (Project #417)
  • Project 2: Innovative approaches to gauge progression of Sturge-Weber syndrome
  • Quantifying Nitrogen Limitation in the Gut Microbiota
  • RNA Dynamics of Transient Macromolecular Complexes in Cancer Cells
  • RNA Operons In Coordinated Gene Expression and Horizontal Transfer
  • RNA localization in neural stem cells during cortical development
  • RNA-Protein Interactions in Flavivirus Infection
  • RNAP II CTD's Role in RNA Transcription and Processing
  • ROCK INHIBITION AS THERAPY FOR CEREBRAL CAVERNOUS MALFORMATION
  • Recombination in yeast
  • Reconstitution of a protective antiviral RNAi response in somatic human cells
  • Regulation of Alternative Splicing of FGFR2 pre-mRNA
  • Regulation of IL7R splicing by DDX39B and its role in Multiple Sclerosis
  • Regulation of Innate Immunity by Virulence Factors
  • Regulation of Salmonella virulence by interspecies methylthioadenosine signaling
  • Regulation of alternative splicing by microenvironment signaling
  • Regulation of antiviral host response by RNA modifications
  • Regulation of human microRNA biosynthesis and activity
  • Regulation of lytic and latent infection by HSV-1 encoded miRNAs
  • Regulation of mitotic genome stability in yeast
  • Regulation of mitotic genome stability in yeast.
  • Regulation of the DLK-1 pathway in axon regeneration
  • Regulation of tumorigenesis by alternative pre-mRNA splicing
  • Regulatory Functions Of Protein Nucleic Acid Interaction
  • Regulatory Functions Of Protein Nucleic Acid Interactions
  • Replicative Mechanisms Of The Negative Strand Viruses
  • Replicative Mechanisms Of The Negative Strand Viruses
  • Replicative Mechanisms Of The Negative Strant Viruses
  • Replicative Mechnaisms Of The Negative Strand Viruses
  • Retinoic Acid And The Curly-Tail Mouse
  • Retinoic Acid Receptors And The Curly-Tail Mouse
  • Retinoid Signaling During Embryogenesis
  • Ribosomal Gene Replication During Magnification
  • Ribosomal Gene Replication During Magnification In Droso
  • Rna Ligands: E2f Function and Cell Proliferation
  • Roche - 2 year
  • Role and mechanism of action of gamma herpesvirus microRNAs
  • Role of Calcineurin in Fungal Virulence
  • Role of Cell Death Pathway in C. elegans Innate Immunity
  • Role of Cholesterol Efflux Blockade in Mycobacterial Infection In Vivo
  • Role of Developmental Signaling Pathways in Tuberculosis Pathogenesis
  • Role of Lectin Genes in C. elegans Innate Immunity
  • Role of RNA-binding proteins in neural stem cell biology and disease
  • Role of cross-link formation in Pol Zeta-dependent mutagenesis in S. cerevisiae
  • S. Cerevisiae: Emergence of an Opportunistic Pathogen
  • SALMONELLA HIJACKING OF STAT3 AND CONSEQUENCES FOR DISEASE
  • STAT3-dependent manipulation of host transcription and immune responses by Salmonella
  • Screening Live Organisms for Mutagenicity
  • Sexual reproduction and virulence of zygomycete fungi
  • Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis
  • Signaling mechanisms by the rapamycin target: Tor kinase
  • Small RNA transcriptome as novel approaches to detect autologous blood transfusion
  • Storage-specific erythrocyte gene signatures to detect autologous transfusion
  • Structural Biological Development of Fungal-Specific Calcineurin Inhibitors
  • Structural Studies of EBV Nuclear Proteins and Host Factors Important for Establishing Latency
  • Structure And Function Of Poxvirus Genes
  • Structure, function, and evolution of the Cryptococcus MAT locus
  • Structure-Function Analysis of Chlamydia Secretion Chaperones
  • Studies Of Cryptococcus Neoformans Assoc With Aids
  • Studies Of Cryptococcus Neoformans Associated With Aids
  • Studies Of Cryptococcus Neoforms Associated With Aids
  • Studies of Cryptococcus neoformans Associated with AIDS
  • Studying Early-Stage Lesions in Mouse Models of Cerebral Cavernous Malformations
  • Subsequent effects of manipulating embryonic neuronal activity
  • Subversion of the host cell cytoskeleton and innate immunity by Chlamydia trachomatis
  • Survival of influenza A virus infected cells and effects on pathogenesis
  • Targeting Apoptosis and Immune Control of Epstein-Barr Virus Infected Tonsillar B Cells
  • Targeting dengue in the mosquito with small molecules
  • Targeting of Interferon-induced host proteins to Legionella-containing vacuoles
  • Targeting the synthetic essential kinases of breast cancers
  • Targeting virally induced inflammation to prevent the development of asthma
  • Targets and functions of the Kaposi's Sarcoma associated herpesvirus microRNAs
  • Temperature-dependent transposon mobilization in Cryptococcus neoformans
  • Temporal regulation of the essential Epstein-Barr virus oncoprotein LMP1
  • The Center for HIV RNA Studies; HIV-1: microRNA interactions
  • The Center for HIV/AIDS-Related Structural Biology
  • The Genetic Basis of Bone Disease in Mycobacterial Infection
  • The Genetic Basis of Bone Disease in Mycobacterial Infection
  • The Genetic Basis of Specific Anosmia
  • The Genomic Analysis of Erythrocyte microRNA in Sickle Cell Diseases
  • The Inhibition Of Inflammatory Processes
  • The Inhibition Of Inflammatory Processes
  • The Structure And Function Of Poxvirus Genes
  • The effects of cells that survive direct influenza A virus infection on lung repair
  • The in vivo roles of PKD1L3 and PKD2L1 in sour taste detection
  • The pathogenic effects of epithelial cells surviving direct influenza virus infection
  • The prevalence and importance of epithelial plasticity in metastatic prostate cancer
  • The role of EBNA3A in the survival of Epstein-Barr Virus-infected tonsillar B cells
  • The role of cyclic-di-AMP in the regulation of Chlamydia cellular functions
  • The role of host RNA-binding proteins in regulating dengue virus replication
  • Tolerance of spontaneous and induced DNA in yeast
  • Topoisomerase 1 and mutagenesis in yeast
  • Topoisomerase-Associated Genome Instability
  • Transcription-associated mutagenesis in yeast
  • Transgenic Approaches To Embryonic Estrogen Receptor Activ
  • Transgenic Study of Embryonic Estrogen Receptor Activity
  • Triangle Zebrafish Group Annual Retreat
  • Triggering human anti-tumor stringent response to target recurrent ovarian cancer
  • US-France Research Proposal: Predicting odorant-dependent and independent olfactory neuron activation based on receptor
  • Understanding the role of N6-methyladenosine in hepatitis C virus infection
  • Using bacterial CRISPR/Cas endonucleases to selectively eliminate HPV-transformed cells in vivo
  • Using natural bacterial interactions to control host-associated microbial communities
  • Variability in the human odorant receptor repertoire
  • Vascular malformation genesis vs. maintenance and progression: identifying the molecular pathways necessary for cerebral cavernous malformation (CCM) maintenance and progression through therapeutic st
  • Vector-delivered CRISPR/Cas as a cure for HSV-1-induced keratitis
  • Viral Inhibition Of Host Defenses
  • Viral Inhibition of Host Defenses
  • Viral Oncology
  • Viral Oncology Training Grant
  • Viral Oncology Training Grant
  • What Happens at a Double Strand Break: Investigating the Role of DNA End Structure in Homologous Recombination
  • Zika virus infection of neural stem cells to model pathogen-induced microcephaly
  • to test whether propranolol will reduce lesion burden and/ or hemorrhage in a mouse model of Cerebral Cavernous malformations

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