Molecular Genetics and Microbiology
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People
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Administrative Positions
- Cullen, Bryan R., Director, Center for Virology
- Garcia-Blanco, Mariano Agustin, Director, Center for RNA Biology
- Heitman, Joseph, Chair, Department of Molecular Genetics and Microbiology
- Marchuk, Douglas Alan, Director, Duke University Program in Genetics and Genomics
- Marchuk, Douglas Alan, Director, Center for Experimental Genetics
- Marchuk, Douglas Alan, Vice Chair, Department of Molecular Genetics & Microbiology
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Professorships
- Cullen, Bryan R., James B. Duke Professor of Molecular Genetics and Microbiology
- Garcia-Blanco, Mariano Agustin, Charles D. Watts Professor of Molecular Genetics and Microbiology
- Heitman, Joseph, James B. Duke Professor of Molecular Genetics and Microbiology
- Joklik, Wolfgang Karl, James B. Duke Professor Emeritus of Medicine
- Keene, Jack Donald, James B. Duke Professor of Molecular Genetics and Microbiology
- Marchuk, Douglas Alan, James B. Duke Professor of Molecular Genetics and Microbiology
- Petes, Thomas Douglas, Minnie Geller Professor of Research in Genetics, in the School of Medicine
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Primary Appointments
- Abaffy, Tatjana, Assistant Research Professor in Molecular Genetics and Microbiology
- Aballay, Alejandro, Adjunct Professor in the Department of Molecular Genetics and Microbiology
- Bastidas, Robert J, Assistant Research Professor in Molecular Genetics and Microbiology
- Cardenas-Corona, Maria Elena, Research Professor of Molecular Genetics and Microbiology
- Chi, Jen-Tsan Ashley, Associate Professor in Molecular Genetics and Microbiology
- Coers, Jorn, Assistant Professor in Molecular Genetics and Microbiology
- Cullen, Bryan R., Professor of Molecular Genetics and Microbiology
- David, Lawrence Anthony, Assistant Professor of Molecular Genetics and Microbiology
- Dietrich, Fred Samuel, Associate Professor of Molecular Genetics and Microbiology
- Dressman, Holly Kloos, Research Professor in Molecular Genetics and Microbiology
- Garcia-Blanco, Mariano Agustin, Adjunct Professor in the Molecular Genetics and Microbiology
- Goldstein, David Benjamin, Adjunct Professor in the Department of Molecular Genetics and Microbiology
- Harrell, Lizzie Johnson, Research Professor Emeritus of Molecular Genetics and Microbiology
- Heaton, Nicholas Scott, Assistant Professor of Molecular Genetics and Microbiology
- Heitman, Joseph, Professor of Molecular Genetics and Microbiology
- Horner, Stacy M., Assistant Professor of Molecular Genetics and Microbiology
- Jinks-Robertson, Sue, Professor of Molecular Genetics and Microbiology
- Joklik, Wolfgang Karl, Professor Emeritus of Molecular Genetics and Microbiology
- Keene, Jack Donald, Professor of Molecular Genetics and Microbiology
- Kim, So Young, Assistant Research Professor in Molecular Genetics and Microbiology
- Ko, Dennis, Assistant Professor in Molecular Genetics and Microbiology
- Kokoska, Robert J, Adjunct Professor in the Department of Molecular Genetics and Microbiology
- Lee, Sunhee, Assistant Research Professor of Molecular Genetics and Microbiology
- Linney, Elwood Albert, Professor Emeritus of Molecular Genetics and Microbiology
- Litvintseva, Anastasia P., Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
- Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology
- Marchuk, Douglas Alan, Professor of Molecular Genetics and Microbiology
- Matsunami, Hiroaki, Professor of Molecular Genetics and Microbiology
- McCusker, John Henry, Associate Professor of Molecular Genetics and Microbiology
- Mieczkowski, Piotr Andrzej, Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
- Mitchell, Thomas Greenfield, Associate Professor Emeritus in Molecular Genetics and Microbiology
- Peng, Hao, Visiting Associate in the Department of Molecular Genetics and Microbiology
- Petes, Thomas Douglas, Professor of Molecular Genetics and Microbiology
- Pickup, David James, Associate Professor of Virology in the Department of Molecular Genetics and Microbiology
- Ramsburg, Elizabeth Anne, Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
- Rawls, John Franklin, Associate Professor of Molecular Genetics and Microbiology
- Scott, Kristin Caruana, Adjunct Assistant Professor in the Department of Molecular Genetics and Microbiology
- Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology
- Sullivan, Beth Ann, Associate Professor of Molecular Genetics and Microbiology
- Sun, Sheng, Assistant Research Professor in Molecular Genetics and Microbiology
- Tobin, David M., Associate Professor of Molecular Genetics and Microbiology
- Valdivia, Raphael H., Professor of Molecular Genetics and Microbiology
- Wang, Shaohui, Visiting Associate in the Department of Molecular Genetics and Microbiology
- Wheat, Robert W., Professor Emeritus of Molecular Genetics and Microbiology
- Yan, Dong, Assistant Professor of Molecular Genetics and Microbiology
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Secondary Appointments
- Abraham, Soman Ninan, Professor in Molecular Genetics and Microbiology
- Alspaugh II, James Andrew, Professor in Molecular Genetics and Microbiology
- Ashley-Koch, Allison Elizabeth, Research Professor in Molecular Genetics and Microbiology
- Cox, Gary Matthew, Assistant Professor in Molecular Genetics and Microbiology
- Crawford, Gregory E., Associate Professor in Molecular Genetics and Microbiology
- Derbyshire, Emily Rose, Assistant Professor in Molecular Genetics and Microbiology
- Diehl, Anna Mae, Professor in Molecular Genetics and Microbiology
- Ferrari, Guido, Associate Research Professor in Molecular Genetics and Microbiology
- Fowler Jr., Vance Garrison, Professor in Molecular Genetics and Microbiology
- Gordan, Raluca Mihaela, Assistant Professor in Molecular Genetics and Microbiology
- Greenleaf, Arno Lee, Professor in Molecular Genetics and Microbiology
- Gregory, Simon Gray, Research Professor in Molecular Genetics and Microbiology
- Gromeier, Matthias, Professor in Molecular Genetics and Microbiology
- Hauser, Michael Arthur, Associate Research Professor in Molecular Genetics and Microbiology
- Klotman, Mary E, Professor in Molecular Genetics and Microbiology
- Koeberl, Dwight D., Professor in Molecular Genetics and Microbiology
- Kuehn, Margarethe Joanna, Associate Professor in Molecular Genetics and Microbiology
- Lew, Daniel Julio, Professor in Molecular Genetics and Microbiology
- Magwene, Paul Mitaari, Associate Professor in Molecular Genetics and Microbiology
- Perfect, John Robert, Professor in Molecular Genetics and Microbiology
- Permar, Sallie Robey, Professor of Molecular Genetics and Microbiology
- Reddy, Timothy E, Assistant Professor in Molecular Genetics and Microbiology
- Rockman, Howard Allan, Professor in Molecular Genetics and Microbiology
- Sherwood, Nina Tang, Assistant Research Professor in Molecular Genetics and Microbiology
- Shinohara, Mari L., Assistant Professor in Molecular Genetics and Microbiology
- Steinbach, William J., Professor in Molecular Genetics and Microbiology
- Sullenger, Bruce Alan, Associate Professor in Molecular Genetics and Microbiology
- Taylor, Gregory Alan, Associate Research Professor in Molecular Genetics and Microbiology
- Thiele, Dennis James, Professor of Molecular Genetics and Microbiology
- Tomaras, Georgia Doris, Professor in Molecular Genetics and Microbiology
- Tsalik, Ephraim, Associate Professor in the Department of Molecular Genetics and Microbiology
- Vilgalys, Rytas J., Assistant Professor in Molecular Genetics and Microbiology
- You, Lingchong, Associate Professor in Molecular Genetics and Microbiology
- Zaas, Aimee Kirsch, Assistant Professor of Molecular Genetics and Microbiology
- Zhuang, Yuan, Professor of Molecular Genetics and Microbiology
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Students
- Hughes, Kelly, Student
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Administers Grant
- 13661osome Movement In Meiosis And Mitosis
- A Combination Therapy Approach to Treating Drug Resistant Fungal Infections
- A Computer Modeling Approach to Create an Antifungal to Improve the Treatment of Cryptococcal Infections
- A Computer Modeling Approach to Create an Antifungal to Improve the Treatment of Cryptococcal Infections
- A Genomics Approach to Study C. neoformans var. grubii
- A Mouse Model of Cerebral Cavernous Malformations
- A Persistent Rna-Dna Hybrid At A T4 Replication Origin
- A Structural Approach for Treating Drug Resistant Fungal Pathogens
- A comprehensive research resource to define mechanisms underlying microbial regulation of host metabolism in pediatric obesity and obesity-targeted therapeutics
- A high througput platform for screening microbial interactions
- A role for pathogen-induced IL-10 production in susceptibility to MS
- ANALYSIS OF GENETICALLY & ENVIRONMENTALLY OVERLAPPING YEAST QUANTITATIVE TRAITS
- Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transporters
- Alfred P. Sloan Research Fellowship for Dr. Lawrence David in Computational & Evolutionary Molecular Biology
- Alternative splicing and epithelial-mesenchymal plasticity in prostate tumors
- Amelioration of neural stem cell defects underlying Zika virus induced microcephaly
- Analysis of the Exon Junction Complex in Neural Development and Microcephaly
- Antitumor Agents And The Bacteriophage T4 Topoisomerase
- BRAIN EAGER: Solving the Code of Olfaction Using Nano-Robot Switchable Odorants
- Basic Mechanisms In Infectious Diseases
- Basic Mechanisms In Infectious Diseases
- Biogenesis of olfactory G protein-coupled receptors
- Boosting innate immunity against Yersinia pestis
- Brain Vasular Malformation Consortium: Predictors of clinical course
- Building archaic hominin olfactory receptors: a functional approach to paleogenomes
- Cell Type-Specific Viral Translation in the CNS
- Cellular Coactivators of the HIV 1 Promoter
- Characterization of Chromosome Fragile Sites in Yeast
- Characterization of a novel Salmonella regulator of IL-10 production and its role in pathogenesis
- Chlamydia Effector Proteins
- Chlamydia co-option of Eukaryotic Lipid Droplets
- Chromosome Movement In Meiosis And Mitosis
- Collaborative Research: Analysis of the Mammalian Olfactory Code
- Comparison of oxidant damage, Nrf2 characteristics, and gene modification of cord blood versus plerixafor-mobilized adult CD34+ cells from sickle cell disease patients
- Connections between mRNA elongation and splicing
- Control of cell fate by progenitor mitosis length and microcephaly-linked genes during cortical development
- Defining novel Riplet-activated antiviral innate immune signaling pathways
- Defining the role of the RNA modification N6-methyladenosine in the hepatitis C virus lifecycle
- Detecting autologous blood doping through the analysis of erythrocyte transcriptome
- Determinants Of Specificity In Protein-Rna Interactions
- Development of BA-1049 for treatment of cerebral cavernous malformations
- Developmental Regulation Of The Glucocortocoid Response
- Dicentric chromosome formation and stability in humans
- Discovering natural bacterial interactions within the human gut microbiota
- Discovery and development of broad spectrum anti-flaviviral drugs
- Disruption of latent HIV-1 proviruses using CRISPR/Cas endonucleases
- Dissecting the role of the exon junction complex in embryonic corticogenesis
- Duke/NIDDK Functional Genomics Center
- Edities Of Cryptococcus Neoformans Associated With Aids
- Effect of APOBEC3G on retroviruses and retrotransposons
- Effect of m6A editing of RNA on influenza A virus replication
- Effect of m6A methylation of HIV-1 transcripts on viral replication
- Embryonal Carcinoma Growth And Differentiation
- Embryonal Carcinoma Growth And Regulation
- Environmental and genetic regulation of copy number variation (CNV)
- Epigenetic Determinants of Centromere Function and Stability in Human Dicentric Chromosomes
- Examination Of The Estrogen Response Pathways In A New Ver
- Forward and Reverse Genetics in Chlamydia
- Function of Mammalian ELAV RNA-Binding Proteins
- Function of alpha herpesvirus microRNAs
- Function of nucleic acid binding DENV host factors
- Function of the Rapamycin Targets: The TOR Kinases
- Functional Characterization of the GNAQ somatic mutation causing Sturge Weber syndrome
- Functional Genomic Analysis of the Chlamydia Inclusion
- Functional Genomic Screens of Tumor Recurrence in Ovarian Cancer
- Functional genomics of human variation to Salmonella invasion
- Fungal-specific drug targets: static vs. cidal starvation & toxic intermediates
- GPCR signaling cascades in Cryptococcus neoformans
- Gene Discovery for Cerebral Cavernous Malformations
- Gene expression Profiling in Mammalian Taste Tissue
- Gene expression programs of lactic acidosis in human cancers
- Gene expression programs of lactic acidosis in human cancers
- Generation of genomic duplications and deletions in yeast
- Genesis and Progression of Cerebral Cavernous Malformations
- Genetic Analysis in Chlamydia
- Genetic Diversity and Complex Traits in S Cerevisiae
- Genetic Mechanisms Affecting Gene Copy Number
- Genetic Mechanisms Affecting Gene Copy Number And
- Genetic analysis in an intractable gut microbe
- Genetic analysis of Cryptococcus neoformans virulence
- Genetic dissection of angiogenesis in the tuberculous granuloma
- Genetic elements of cancer cell survival in tumor microenvironment stresses
- Genetic regulation of genome stability in yeast
- Genetic regulation of genome stability in yeast
- Genetically stable Picornavirus HIV Immunization vectors
- Genetics of Cryptococcus sexual reproduction
- Genetics of Hereditary Hemorrhagic Telangiectasia
- Genomic and Epigenetic Mechanisms of Human Centromere Assembly and Chromosome Stability
- HOST GENETIC VARIATION REGULATING SALMONELLA INVASION AND DISEASE SUSCEPTIBILITY
- High throughput S. cerevisiae HAM, GWA & QT/QTL architecture
- Host Innate Immune-Microbial Interactions in Intestinal Inflammation
- Host pathways regulating Epstein-Barr virus-mediated B cell growth transformation
- Host-mediated lysis of cytoplasmic pathogens
- Host-pathogen interactions in hepatitis C virus replication
- Human Genetic Variance and Cellular Responses to Sexually Transmitted Infections
- Human Stringent Response as Novel Therapeutic Approaches for Breast Cancers
- IRGM-driven host responses to Chlamydia trachomatis infections
- Identification of Coxiella burnetti Effector Proteins
- Identification of Modifier Genes in Heart Disease
- Identification of genetics modifiers of heart disease
- Identifying genes required for digestive physiology and lipid metabolism
- Identifying the CCM3 Gene: Understanding Familial Stroke
- Imaging Alternative Splicing During Tumor Progression
- Immune Compromised Zebrafish for Cell Transplantation
- Implications of 14-3-3 in topoisomerase II pharmacology
- Improvement of genetic analysis in the pathogenic zygomycete Mucor circinelloides
- In vivo patterns of receptor activation by odorants
- Influenza virus small RNAs
- Initiation Of Dna Replication In The Phage T4 System
- Initiation Of Dna Replication In The Phage T4 Systems
- Initiation Of T4 Replication: Study Of An Rna-Dna Hybrid
- Initiation of T4 Replication - Study of an RNA/DNA Hybrid
- Innate Immune Regulation during hepatitis C virus infection
- Innate immune recognition of bacterial secretion systems by GBPs
- Integrated instrument systems for maintenance and delivery of RNAi libraries
- Interferon-driven ubiquitin response targets Chlamydia inclusions in human cells
- Introducing Genetic Material Into Stem Cells
- Investigating the Type II Secretion System of Chlamydia trachomatis
- Investigating the function of the Mcgl Family
- Investigating the origin of spontaneous mitotic homologous recombination in Saccharomyces cerevisiae
- Investigation of the two-hit hypothesis for Cerebral Cavernous Malformations
- IsoCyte Laser Scanning Plate Cytometer for High-throughput, High-content Assays
- Iterative Cloning A Novel Approach To Quantitative Genetic
- Linking oxygen and bacterial ecology in necrotizing enterocolitis
- Macromolecular Synthesis In Virus-Infected Cells
- Macromolecular Synthesis In Virus-Infected Cells
- Macromolecular Synthesis Of Virus-Infected Cells
- Macrophage Reprogramming During Granuloma Formation in the Zebrafish
- Mechanisms of Centromere Function
- Mechanisms of Human Chromosome Rearrangement and Stability
- Mechanisms of neural circuit formation in C. elegans
- Mechanisms of neural progenitor division in the developing brain
- Microbial Ecology of the Zebrafish Intestine
- Microbial Regulation of Nuclear Receptor Activity in the Intestinal Epithelium
- Microbial regulation of host nutrient metabolism
- Microfluidic PCR Platform to Detect Microbial DNA
- Mitochondrial DNA Stability and Mutagenesis
- Modulating Eicosanoids to Treat Tuberculosis: Personalized, Host-directed Therapy
- Modulation of Host Cell Environment by Mycobacterial PE/PPE Proteins
- Modulation of Odorant Receptor Function
- Molecular Biology Of The Ro-Rnp Autoantigen
- Molecular Identification of Pathogenic Fungi
- Molecular Mechanism of HIV-1 Vif Function
- Molecular Mechanisms Underlying Odorant Recognition
- Molecular Mechanisms Underlying Specific Anosmia and Sensitization
- Molecular Mycology and Pathogenesis Training Program
- Molecular Targeting of Breast Cancer
- NSF sponsored conference
- Natural genetic variation regulating infarct volume
- Novel Antifungal Therapeutic Approaches
- Nuclear, mitochondrial and L-A virus contributions to yeast quantitative traits
- Olfactory moding in mammals
- Oncogenic Gene Regulatory Networks
- Organization and Regulation of Eukaryotic Centromeres
- Organization and Stability of Centromeric Chromatin
- Organotin influences on assembly and obesogenic activity of the gut microbiota
- Peripheral Odor Coding in Mammals
- Phase I enzymes as part of an epigenetic switch
- Phase Variation in Saccharomyces cerevisiae
- Post-transcriptional RNA regulation in mammalian neural stem cells
- Post-transcriptional coordination by HuR and microRNAs during tumorigenesis
- Posttranscriptional Gene Regulation in T Cell Activation
- Posttranscriptional regulation of the Wnt pathway by HuR and microRNAs
- Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors
- Production of non-pathogenic oncolytic poliovirus chimeras for the treatment of brain tumors (Project #417)
- Project 2: Innovative approaches to gauge progression of Sturge-Weber syndrome
- Quantifying Nitrogen Limitation in the Gut Microbiota
- RNA Dynamics of Transient Macromolecular Complexes in Cancer Cells
- RNA Operons In Coordinated Gene Expression and Horizontal Transfer
- RNA localization in neural stem cells during cortical development
- RNA-Protein Interactions in Flavivirus Infection
- RNAP II CTD's Role in RNA Transcription and Processing
- ROCK INHIBITION AS THERAPY FOR CEREBRAL CAVERNOUS MALFORMATION
- Recombination in yeast
- Reconstitution of a protective antiviral RNAi response in somatic human cells
- Regulation of Alternative Splicing of FGFR2 pre-mRNA
- Regulation of IL7R splicing by DDX39B and its role in Multiple Sclerosis
- Regulation of alternative splicing by microenvironment signaling
- Regulation of antiviral host response by RNA modifications
- Regulation of human microRNA biosynthesis and activity
- Regulation of lytic and latent infection by HSV-1 encoded miRNAs
- Regulation of mitotic genome stability in yeast
- Regulation of mitotic genome stability in yeast.
- Regulation of the DLK-1 pathway in axon regeneration
- Regulation of tumorigenesis by alternative pre-mRNA splicing
- Regulatory Functions Of Protein Nucleic Acid Interaction
- Regulatory Functions Of Protein Nucleic Acid Interactions
- Replicative Mechanisms Of The Negative Strand Viruses
- Replicative Mechanisms Of The Negative Strand Viruses
- Replicative Mechanisms Of The Negative Strant Viruses
- Replicative Mechnaisms Of The Negative Strand Viruses
- Retinoic Acid And The Curly-Tail Mouse
- Retinoic Acid Receptors And The Curly-Tail Mouse
- Retinoid Signaling During Embryogenesis
- Ribosomal Gene Replication During Magnification
- Ribosomal Gene Replication During Magnification In Droso
- Rna Ligands: E2f Function and Cell Proliferation
- Roche - 2 year
- Role and mechanism of action of gamma herpesvirus microRNAs
- Role of Calcineurin in Fungal Virulence
- Role of Cholesterol Efflux Blockade in Mycobacterial Infection In Vivo
- Role of Developmental Signaling Pathways in Tuberculosis Pathogenesis
- Role of cross-link formation in Pol Zeta-dependent mutagenesis in S. cerevisiae
- S. Cerevisiae: Emergence of an Opportunistic Pathogen
- Screening Live Organisms for Mutagenicity
- Sexual reproduction and virulence of zygomycete fungi
- Signaling Aberrations and Cerebral Cavernous Malformation Pathogenesis
- Signaling mechanisms by the rapamycin target: Tor kinase
- Small RNA transcriptome as novel approaches to detect autologous blood transfusion
- Structural Biological Development of Fungal-Specific Calcineurin Inhibitors
- Structural Studies of EBV Nuclear Proteins and Host Factors Important for Establishing Latency
- Structure And Function Of Poxvirus Genes
- Structure, function, and evolution of the Cryptococcus MAT locus
- Structure-Function Analysis of Chlamydia Secretion Chaperones
- Studies Of Cryptococcus Neoformans Assoc With Aids
- Studies Of Cryptococcus Neoformans Associated With Aids
- Studies Of Cryptococcus Neoforms Associated With Aids
- Studies of Cryptococcus neoformans Associated with AIDS
- Studying Early-Stage Lesions in Mouse Models of Cerebral Cavernous Malformations
- Subsequent effects of manipulating embryonic neuronal activity
- Survival of influenza A virus infected cells and effects on pathogenesis
- Targeting Apoptosis and Immune Control of Epstein-Barr Virus Infected Tonsillar B Cells
- Targeting dengue in the mosquito with small molecules
- Targeting of Interferon-induced host proteins to Legionella-containing vacuoles
- Targeting the synthetic essential kinases of breast cancers
- Targets and functions of the Kaposi's Sarcoma associated herpesvirus microRNAs
- Temperature-dependent transposon mobilization in Cryptococcus neoformans
- Temporal regulation of the essential Epstein-Barr virus oncoprotein LMP1
- The Center for HIV RNA Studies; HIV-1: microRNA interactions
- The Genetic Basis of Bone Disease in Mycobacterial Infection
- The Genetic Basis of Bone Disease in Mycobacterial Infection
- The Genetic Basis of Specific Anosmia
- The Genomic Analysis of Erythrocyte microRNA in Sickle Cell Diseases
- The Inhibition Of Inflammatory Processes
- The Inhibition Of Inflammatory Processes
- The Structure And Function Of Poxvirus Genes
- The effects of cells that survive direct influenza A virus infection on lung repair
- The in vivo roles of PKD1L3 and PKD2L1 in sour taste detection
- The prevalence and importance of epithelial plasticity in metastatic prostate cancer
- The role of cyclic-di-AMP in the regulation of Chlamydia cellular functions
- The role of host RNA-binding proteins in regulating dengue virus replication
- Tolerance of spontaneous and induced DNA in yeast
- Topoisomerase 1 and mutagenesis in yeast
- Topoisomerase-Associated Genome Instability
- Transcription-associated mutagenesis in yeast
- Transgenic Approaches To Embryonic Estrogen Receptor Activ
- Transgenic Study of Embryonic Estrogen Receptor Activity
- Triggering human anti-tumor stringent response to target recurrent ovarian cancer
- US-France Research Proposal: Predicting odorant-dependent and independent olfactory neuron activation based on receptor
- Understanding the role of N6-methyladenosine in hepatitis C virus infection
- Using bacterial CRISPR/Cas endonucleases to selectively eliminate HPV-transformed cells in vivo
- Using natural bacterial interactions to control host-associated microbial communities
- Variability in the human odorant receptor repertoire
- Vector-delivered CRISPR/Cas as a cure for HSV-1-induced keratitis
- Viral Inhibition Of Host Defenses
- Viral Inhibition of Host Defenses
- Viral Oncology
- Viral Oncology Training Grant
- Zika virus infection of neural stem cells to model pathogen-induced microcephaly