Ophthalmology, Vitreoretinal Diseases & Surgery
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Administers Grant
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A Long-term Follow-Up Study to Evaluate the Safety and Efficacy of Suprachoroidal Administration of RGX-314 for
Diabetic Retinopathy Without Center Involved-Diabetic Macular Edema
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A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF LAMPALIZUMAB IN PATIENTS WITH GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION WHO HAVE COMPLETED A ROCHE¿SPONSORED STUDY
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A MULTICENTER, PROSPECTIVE, OBSERVATIONAL STUDY OF THE PROGRESSION OF INTERMEDIATE AGE-RELATED MACULAR DEGENERATION
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A PHASE III, MULTICENTER, RANDOMIZED STUDY OF THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF
THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH
DIABETIC RETINOPATHY (PAVILION)
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A Phase 2 Multicenter, Randomized, Double-Masked, Sham-Controlled Study of the Safety and Efficacy of Intravitreal Injections of NGM621 in Subjects with Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) (CATALINA)
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A Phase 2 Randomized, Double-Masked, Dose-Ranging Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults with Active Non-Infectious Intermediate-, Posterior-, and Panuveitis
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A Phase 2, Double-Masked, Placebo-Controlled, Dose Range Finding Study of Danicopan (ALXN2040) in Patients with Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
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A Phase 3 open-label, multicenter, extension study to evaluate the long-term safety and efficacy of
pegcetacoplan in subjects with geographic atrophy secondary to age-related macular degeneration
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A Phase III, Multicenter, Randomized, Visual Assessor-Masked, Active-Comparator Study of the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System with Ranibizumab in Patients with Diabetic Macular Edema
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A Randomized, Partially Masked, Controlled, Phase 2b/3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD (ATMOSPHERE)
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A Randomized, Partially Masked, Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD
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A cross-sectional study of multimodal retinal and choroidal imaging in three well-characterized cohorts - Alzheimer's disease, mild cognitive impairment, normal cognition - in the Duke-UNC Alzheimer's Disease Research Collaborative.
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A deep learning model using multimodal retinal imaging for detection of patients with genetic predisposition for development of Alzheimer's disease
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A multicenter, randomized, controlled, prospective, adaptive Phase 3 clinical trial of repeated intravitreal injections of ADX-2191 versus standard-of-care for the prevention of proliferative vitreoretinopathy
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A retrospective study of subjects previously enrolled in ADX-2191-PVR-001, assessing the
development of epiretinal membranes post silicone oil removal
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APL2-304
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AREDS2 10-Year Follow-on
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ARIS: AMD Ryan Initiative Study
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Activation of Cellular Proteostasis as an Approach to Treat Inherited Retinal Degenerations
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An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects with Intermediate Age-Related Macular Degeneration
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Analyzing retinal microanatomy in retinopathy of prematurity to improve care
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BIMD - Collaborate Research Agreement
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Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants
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Blood Retinal Barrier in Retinopathy of Prematurity
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Center Core Grant for Vision Research
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Clinical Research Fellowship - David Le
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Comparison of subretinal bleb volumes created by ab-externo and ab-interno approaches using microscope-integrated optical coherence tomography.
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Complement factor H modulates lipoprotein clearance in AMD
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Cytokine Modulation In Proleferative Vitreoretinopathy
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Cytokine Modulation In Proliferative Vitreoretinopathy
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Cytokine Modulation In Proliferative Vtreoretinopathy
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DE-109 LUMINA
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Diabetic Retinopathy Vitrectomy Study (Drvs)
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Differential multimodal retinal imaging in biomarker-positive subjects with Alzheimer's disease and mild cognitive impairment characterized by neuroimaging and neurochemical analysis.
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Dose range finding study for AAV8.CBA.humanFH vectors in CFH-deficient Mice
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Elucidating perifoveal vascular development in infants
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Evaluating the Retinal Structure and Microvasculature in Mild and Moderate Traumatic Brain Injury (TBI) using Multimodal Retinal Imaging.
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Evaluation of KPI-012's protective effects on RPE cells
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Evaluation of chronic effects of electronic cigarette aerosol inhalation on macular perfusion using optical coherence tomography angiograph
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Evaluation of retinal cavitations in macular telangiectasia type 2 and response to ciliary neutrophic factor (CNTF)
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Evaluation of the Heidelberg Engineering SPECTRALIS with Flex Module for In-vivo Imaging in the Supine Position
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Evaluation of the Safety and Efficacy of Sustained Release Dexamethasone Intracanalicular Insert (Dextenza) in pediatric patients following retinal surgery or laser treatment under anesthesia (TENDER)
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Exploring the role of ERR Alpha (Estrogen Related Receptor Alpha) in the eye as a function of age and AMD (Age related Macular Degeneration)
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Full-thickness macular hole and vitreomacular interface changes in Coats' disease
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GR43828 - A Phase I, Multicenter, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of RO7446603 Alone and Co-Administered with Aflibercept in Patients with Diabetic Macular Edema
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GX29633 PROXIMA
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Gemini Therapeutics, Inc.- SRA
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Gene therapy treatment of neurodegeneration using proteasome activators
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HDL - a therapeutic target for age related macular degeneration.
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HORIZON: A Phase II, Open-Label, Outcomes-Assessor Masked, Multicentre, Randomised, Controlled Study To Evaluate The Safety And Efficacy Of TwoDoses Of Gt005 Administered As A Single Subretinal Injection In Subjects With Geographic Atrophy Secondary
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IPA - Isabelle Doan
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Identification of novel contributors to retinitis pigmentosa using metabolic and proteomic approaches
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Investigating the role of a novel nuclear receptor in aging and AMD.
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LXR as a novel therapeutic target in diabetic retinopathy
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LXR as a novel therapeutic target in diabetic retinopathy
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Lightside III CSP005
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Longitudinal assessment of choroidal vascularity index, subfoveal choroidal thickness, and central
subfield thickness in treatment-naive eyes with cystoid macular edema due to branch retinal vein occlusion
compared to unaffected fellow eyes
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Macrophages and Treatment-Resistant NVAMD
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Mechanisms of photoreceptor disc maturation
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Mechanisms of photoreceptor protein transport and compartmentalization
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Mitochondrial Dysfunction in a New Model of Dry AMD
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Modulation Of Na+K+ Atpase In Retinal Detachment
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Monocytes in Dry Age-Related Macular Degeneration
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Muller glial dysfunction in retinal edema
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Novel signaling pathways regulated by the liver x receptor in age-related macular degeneration
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Nuclear receptor driven mechanisms in aging and AMD
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OCT Guidance and Grading
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Optical Coherence Tomography Angiography Fractal Dimension Analysis in Alzheimer¿s Disease
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Optos ultrawidefield retinal image management and biomarker analysis in neurodegenerative disease
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PAN-01-102 - Multicenter Phase I/II Study to Evaluate Safety and Tolerability of Pan-90806 Eye Drops Suspension in Treatment-Naive Participants with Neovascular Age-Related Macular Degeneration (AMD)
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Pathological and functional consequences of dimerization-deficient rhodopsin mutations
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Preclinical Testing of Complement Factor H Gene Augmentation Therapy to Treat Dry AMD
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RPE Exosomes in Age-related Macular Degeneration
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Rate of Progression of PCDH15 Related Retinal Degeneration
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Regulation of Macrophage-Mediated Neovascular Remodeling in Neovascular AMD
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Regulation of inflammation and lipid homeostasis by the aryl hydrocarbon receptor in age-related macular degeneration
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Repeatability, Reproducibility, and Characterization of Choroidal Vascularity Index (CVI) in Handheld versus Tabletop OCT images in adults and premature infants
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Retinal Imaging with Optical Coherence Tomography in Neonatal Brain Injury to Evaluate and Improve Visual and Neurologic Outcomes
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Retinal Neurovascular Patterning in Preterm Infants
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Rhodopsin dimerization: mechanistic basis and functional consequences
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Role of Proteasome Overload in Pathogenesis of Retinitis Pigmentosa
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SPIAM-202 - Age-Related Macular Degeneration with Geographic Atrophy
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Screening for pediatric retinal diseases using artificial intelligence and wide-field fundus imaging
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Secondary Data Analysis for Neonates with Retinal OCT Imaging
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Semi-Automated Vessel Analysis of Posterior Pole Vessel Maps Generated from Bedside Optical Coherence Tomography for Retinopathy of Prematurity Screening
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Serum Anti-AAV8 Neutralizing Antibody Assessment Study of Patients with Neovascular Age-related Macular Degeneration or Diabetic Retinopathy
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Study evaluating the safety and clinical response of sub-retinal administration of CNTO 2476 in subjects with visual acuity impairment associated with Geographic Atrophy Secondary to Age Related Macular Degeneration
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Subretinal drug delivery via a novel ab-externo approach using microscope integrated optical coherence tomography
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Testing Gene Therapy in Models of Geographic Atrophy
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Testing the effect of a CFH agonistic monoclonal PEG-Fab
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The Impact of Choroidal Thickness in Retinopathy of Prematurity: A Longitudinal Stud
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The Role of Alpha-Melanocyte Stimulating Hormone in Alzheimer's and Ocular Disease
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The Role of RPE-derived Exosomes in Deposit Formation and ECM Modulation
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The role of ADAM9 in retinal health and disease
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Understanding the function of PRCD, a small protein whose mutations cause blindness
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Understanding the roles of ectosomes and the associated microglial response in photoreceptor degeneration
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Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated with Rare Disease-Causing Genetic Variants
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Using Optical Coherence Tomography Angiography to Analyze Development of Pediatric Retinal Vasculature
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Visualizing Retinal Vascular Development and Pathology in Infants
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Vitamin A Supplementation to Alleviate Night Vision Impairment in Choroideremia Patients
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Volumetric Measurement of Subretinal Blebs Created with Orbit Subretinal Delivery Device and Using Microscope-Integrated Optical Coherence Tomography