Surgery, Surgical Sciences

• 

  People

  • Administrative Positions

    • Asokan, Aravind, Director of Gene Therapy
    • Tomaras, Georgia Doris, Chief, Division of Surgical Sciences

  • Professorships

    • Bolognesi, Dani Paul, James B. Duke Distinguished Professor Emeritus of Medicine
    • Lyerly, Herbert Kim, George Barth Geller Distinguished Professor of Immunology
    • Marks, Jeffrey R., Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
    • Sullenger, Bruce Alan, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery
    • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery

  • Primary Appointments

    • Acharya, Priyamvada, Associate Professor in Surgery
    • Asokan, Aravind, Professor in Surgery
    • Bhavsar, Nrupen, Associate Professor in Surgery
    • Bolognesi, Dani Paul, Professor Emeritus of Surgery
    • Bowles, Dawn Elizabeth, Assistant Professor in Surgery
    • Chen, Chin-Ho, Professor in Surgery
    • Cheng, Qing, Associate Professor in Surgery
    • Crosby, Erika J, Assistant Professor in Surgery
    • Dahl, Shannon L, Adjunct Assistant Professor in the Department of Surgery
    • Devi, Gayathri R., Professor in Surgery
    • Ferrari, Guido, Professor in Surgery
    • Hartman, Zachary Conrad, Associate Professor in Surgery
    • Hobeika, Amy Claudine, Assistant Professor in Surgery
    • Holl, Eda K, Adjunct Assistant Professor in the Department of Surgery
    • Huang, Li, Assistant Professor in Surgery
    • Jost, Stephanie Rachel, Associate Professor in Surgery
    • Kabiri, Zahra, Assistant Professor in Surgery
    • Krauchanka, Yuliya, Assistant Professor of Surgery
    • LaBranche, Celia Crane, Associate Professor Emeritus
    • Lyerly, Herbert Kim, Professor of Surgery
    • Manickam, Cordelia, Assistant Professor in Surgery
    • Marks, Jeffrey R., Professor in Surgery
    • Montefiori, David Charles, Professor in Surgery
    • Nair, Smita K, Professor in Surgery
    • Osada, Takuya, Adjunct Associate Professor in the Department of Surgery
    • Pollara, Justin Joseph, Associate Professor in Surgery
    • Reeves, Roger Keith, Professor in Surgery
    • Rogers, Bruce W, Assistant Professor in Surgery
    • Saunders, Kevin O'Neil, Associate Professor in Surgery
    • Sekaran, Moses, Assistant Professor in Surgery
    • Shen, Xiaoying, Associate Professor in Surgery
    • Snyder, Joshua Clair, Associate Professor in Surgery
    • Sullenger, Bruce Alan, Professor in Surgery
    • Tomaras, Georgia Doris, Professor in Surgery
    • Tuyishime, Marina, Medical Instructor in the Department of Surgery
    • Weinhold, Kent James, Professor in Surgery
    • Williams, Kyha Denise, Assistant Professor in Surgery
    • Williams, Wilton Bryan, Associate Professor in Surgery
    • Xu, He, Associate Professor of Surgery
    • Yi, John S, Adjunct Assistant Professor in the Department of Surgery

  • Secondary Appointments

    • Ingram, Jennifer Leigh, Assistant Professor in the Department of Surgery
    • Kelsoe, Garnett H., Associate Professor in the Department of Surgery
    • McCall, Shannon Jones, Associate Professor in Surgery
    • Morse, Michael Aaron, Professor in the Department of Surgery

  • Joint Appointments

    • Gersbach, Charles, Associate Professor of Surgery

  • Non-Faculty Positions

    • Raji, Sara, Research Scholar
• 

  Administers Grant

  • 14th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST 2020)
  • 17th INTERNATIONAL CONFERENCE ON HIV TREATMENT, PATHOGENESIS, AND PREVENTION RESEARCH (INTEREST)
  • A Molecular Framework for Understanding DCIS
  • A Neoepitope Subunit Vaccine Targeting the Mutated Estrogen Receptor Ligand Binding Domain to Treat and Prevent Endocrine Resistant ER+ Breast Cancer
  • A PHASE 2a, RANDOMIZED, OBSERVER-BLIND, PLACEBO-CONTROLLED, DOSE-CONFIRMATION STUDY TO EVALUATE THE SAFETY, REACTOGENICITY, AND IMMUNOGENICITY OF MRNA-1273 SARS-COV-2 VACCINE IN ADULTS AGED 18 YEARS A
  • A Phase 1, Randomized, Observer-Blind, Dose-Ranging Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 and mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18-55 Years
  • A Phase 2/3, Two-Part, Open-Label, Dose-Escalation, Age De-escalation and Randomized, Observer-Blind, Placebo-Controlled, Expansion Study to Evaluate the Safety, Tolerability, Reactogenicity, and Effe
  • A Phase 3b, Open-Label, Safety and Immunogenicity Study of SARS-CoV-2 mRNA-1273 Vaccine in Adult Solid Organ Transplant Recipients and Healthy Controls
  • AAV-Exosomes: Escaping Neutralizing Antibody and Enhancing Delivery
  • Analysis Of A Cd4-Independent Hiv-1/Iiib Envelope
  • Aptamer-small molecule conjugate as potent and reversible surgical anticoagulants
  • Awakening Endogenous Retroviruses with the Space Environment
  • BATF3+ Dendritic Cells for the Treatment of Malignant Gliomas
  • BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy
  • Beyond PD1: An immunotherapeutic strategy to stimulate and enable both T-cell and B-cell responses in immunosuppressive and non-mutated metastatic breast cancer
  • Breast Cancer Detection Consortium
  • Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Non-human Primates
  • Cas9 RNP delivery to immune cells in vivo via molecular targeting
  • Center for AIDS Research (CFAR)
  • Characterization of Recombinant Adeno-Associated Viral Vectors
  • Characterizing the Neutralizing Antibody Response in SARS-CoV-2 Infected Individuals
  • CircRNAs and CNS Gene Transfer
  • CoVPN 3001 A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine
  • CoVPN 3003 A Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older
  • CoVPN 3005: Efficacy, Immunogenicity, and Safety of Two SARS-CoV-2 Recombinant Protein Vaccines with Adjuvant in Adults 18 Years of Age and Older
  • CoVPN 3008 Multi-Center, Randomized, Efficacy Study of Early vs Deferred Vaccination with COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern
  • CoVPN 5001 A Prospective Study of Acute Immune Responses to SARS-CoV-2 Infection
  • Combined Hepatitis B and HIV-1 Envelope Infant Vaccination to Augment T cell Help through Enhanced Linked Recognition
  • Comparing HIV Mucosal Targets in US and Kenyan Populations
  • Defining a CXCR3-associated gene signature as a predictive biomarker and alternate target of immunotherapy across molecular subtypes of breast cancer
  • Detection and Elimination of Oncogenic Signaling Networks in Pre-malignant and Malignant Cells with Magnetic Resonance Imaging
  • Determinants of AAV Tropism
  • Determinants of geographic disparities in mortality and multimorbidity in the U.S.
  • Developing a HER3 Vaccine to Prevent Resistance to Endocrine Therapy
  • Direct Detection and Characterization of Blood Clots In Vivo
  • Efficacy of replicon-encapsulated lipid nanoparticles for vaccination against breast cancer in vivo
  • Enabling effective anti-tumor immunity from targeted antibodies through dual innate and adaptive immune checkpoint blockade in non-immunogenic cancers
  • Engineering cellular secretion for gene delivery
  • Escape of maternal plasma broadly neutralizing antibody responses as a mechanism of mother to child HIV transmission
  • Establishing the molecular and cellular mechanisms of Lgr5 signaling for controlling cancer stem cell behavior
  • Evolving High Potency AAV Vectors for Neuromuscular Genome Editing
  • Evolving novel AAV vectors for gene therapy to cure HIV
  • Exploring Dual-Affinity Re-Targeting Proteins for Cure of Pediatric HIV-1 Infection
  • Fortilin, CTNNA3, and the Heart
  • GH-VAP: Duke Antibody Dynamics Core Extension; INV-008612 Supplement
  • GHDC Antibody Dynamics Core
  • Gene Therapy Countermeasure for Detrimental Effects of Space Radiation
  • HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals
  • HVTN 705 Case Control Janssen
  • HVTN 705 Pilot
  • HVTN LC
  • HVTN Laboratory Center: 702 PF
  • HVTN Laboratory Center: Phase 1 PF
  • HVTN Leadership and Operations Center (LOC)
  • HVTN TB Supplement
  • Hebei Bio-High Technology Visiting Researcher Training
  • Heterosubtypic immunity to influenza virus mediated by MHC-E-restricted memory NK cells
  • Identifying Novel Intensity-Specific Regulators of RAS Signaling
  • Immune Responses to Malaria, HIV and SARS-CoV-2 Infection and Immunization
  • Immunotherapeutic Targeting of a Therapy Resistant Oncogenic HER2 Isoform
  • Impact of Fc N-glycan structure on HIV-specific antibody functions
  • Improving Cardiac Transplant Outcomes Through PD-L1 Overexpression Gene Therapy
  • Improving transplant organ survival through the mitigation of donor-derived mitochondrial damage-associated molecular patterns
  • Investigating the adaptive immune response to dormant tumor cells
  • Investigation of LAMP anti-tumor vaccines
  • Investigation of stimulating stress response mechanisms to enhance antibody dependent cellular phagocytosis
  • Maternal oral influenza & SARS-CoV2 vaccination for generation of potently neutralizing sIgA antibodies in breast milk
  • Methylomic Basis of Survival Disparities Among Black and White Women With High-Grade Serous Ovarian Cancer
  • Mitigating inflammation using nucleic acid scavengers to prevent breast cancer metastasis
  • Moderna mRNA-1273 P201 (Part B) Trial Neutralizing Antibody Assessment
  • Moderna mRNA1275 P205 Trial Neutralizing Antibody Assessment
  • Molecular Determinants of Health Disparities in Inflammatory Breast Cancer
  • Molecular and Immunologic Characterization of In-Transit Melanoma
  • Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color
  • NK cell responses to JC polyomavirus
  • NONHUMAN PRIMATE TESTING CENTER FOR EVALUATION OF SOMATIC CELL GENOME EDITING TOOLS
  • Natural killer cell receptor-expressing B cells as regulators of mucosal immunity in SIV infection
  • Neutralizing Antibody Assessment for SARS-CoV-2 Vaccine Trials
  • Neutralizing Antibody Response Assessment for a Phase 2/3 Randomized, Observer-Blind, Placebo-Controlled, Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 SARS-CoV-2 Vaccin
  • New Non-Nuceleotide Reverse Transcriptase Inhibitors for Drug Resistant HIV Strains
  • Next Generation AAV Vectors for Kidney Gene Therapy
  • Next Generation Broadly Neutralizing Antibodies to Clear HIV-1 Reservoir
  • Nonhuman Primate Core Humoral Immunology Laboratory for AIDS Vaccine Research and Development
  • Nonhuman Primate Option 18
  • Nonhuman Primate Option 9
  • Nuclear EGFR Signaling Network in Human Cancer
  • Only the strong survive: Microenvironmental and genetic determinants of organotropism
  • Ovarian Cancer Survival in African-American Women
  • Overcome Stress Signaling to Prevent Inflammatory Breast Cancer Metastasis
  • PRO HIV-013 Humoral Immune Response
  • Peptides Models of Two Helical Regions in GP41 Ectodomain
  • Personalized T-cell immunity against metastatic TNBC using MAVS immunostimulation
  • Plant Anti-HIV Agents
  • Primate Contract Expansion for Covid-19
  • Project 2: RNA vaccination in early life to induce potent and broad HIV Env-specific antibody responses
  • Project 2: Synthetic DNA & Novel Env Vaccine for HIV
  • Project 3: RNA Aptamers as Probes and Regulators of Coagulation
  • Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration
  • RE-ENGINEERING AAV GENOME PACKAGING
  • Radiation Resistance Conferred by Small Proline Rich Proteins (SPRRs)
  • Recording the natural history of cancer progression using a Crainbow model of HER2+ breast cancer
  • Reducing prostate cancer aggressiveness via aptamer-mediated nuclear delivery of splice-switching oligonucleotides
  • Reduction of Brain AVM Severity through Inhibition of Pathogenic Angiogenesis
  • Regional Oncolytic Poliovirus Immunotherapy for Breast Cancer
  • Role of eosinophils in SIV infection
  • Role of maternal-fetal interface NK cells in pregnancy maintenance and congenital CMV transmission
  • Same
  • Sanofi Coronavirus Studies
  • Study of LAMP Vaccines in HER2+ Breast Cancer
  • Synthetic DNA launched & adjuvanted Immune Focused Env immunogens for HIV
  • TCGA - Breast Cancer Tissue Acquisition
  • Targeting the Progesterone Receptor as a Novel Means to Increase Efficacy of Immune Checkpoint Inhibitors in Hormone Receptor Positive Breast Cancer
  • Translational Research in Surgical Oncology
  • Visualizing tumor heterogeneity in an immune intact and autochthonous mouse model of breast cancer

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