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Administers Grant
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A Consensus Conference on Treatment Guidelines for Myasthenia Gravis (ad hoc)
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A DB, Randomized, Placebo Controlled, Parallel Group Study to Qualify a Biomarker Algorithm for Risk of Developing MCI due to AD and to Test the S&E of Pioglitazone (AD-4833 SR 0.8 mg QD) Delay Onset of MCI due AD in Cognitively Normal Subjects.
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A Mouse Model of Inflammation in Alzheimer's Disease
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A PHASE 2B/3, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 12 MONTH CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF MN-166 (IBUDILAST) FOLLOWED BY AN OPEN-LABEL EXTENSION IN SUBJECTS WITH AMYOTROPHIC LATERAL SCLEROSIS
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A Phase 1b Multicenter, Open-Label, Single Ascending Dose Study to Evaluate the Safety and Tolerability of PF-06939926 in Ambulatory Subjects with Duchenne Muscular Dystrophy" Protocol # C3391001 (hereinafter the "Study")
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A Phase 2 Pharmacodynamic Study of Ezogabine on Neuronal Excitability in Amyotrophic Lateral Sclerosis
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A Phase 2 Randomized, Double Blind, Placebo-Controlled, Multiple Ascending dose study to evaluate Safety,Efficacy, and Pharmacokinetics and Pharmacodynamics of PF 06252616 in Ambulatory boys with Duchenne Muscular Dystrophy.
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A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of NP001 in Subjects with Amyotrophic Lateral Sclerosis (ALS) and Evidence of Elevated Systemic Inflammation
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A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, Study to Evaluate the Safety, Tolerabiliity and Efficacy of Tirasemtiv in Patients with Amyotrophic Lateral Sclerosis ( ALS)
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A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) Who Completed VITALITY -ALS (CY 4031)
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A Phase II, Dose Finding Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NS-065/NCNP-01 in Boys with Duchenne Muscular Dystrophy (DMD)
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A Pilot Trial of Triheptanoin for People with Amyotrophic Lateral Sclerosis (PALS)
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A Randomized,Cross-Over,Controlled Feasibililty and Validation Study of a Self-Adminstered Memory Screening Test with Automated Reporting(SAMSTAR) inNormal Control subjects and Subjects with MCI, age 55-84
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ALS Telemedicine
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ALS Telemedicine
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ALS Telemedicine
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ALSUntangled
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An Open label, Long Term Safety Study of SD-809 Er in Subjects wtih Chorea associated with Huntington's Disease.
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An open-label extension study of the long-term safety, tolerability and efficacy of drisapersen in US and Canadian subjects with Duchenne Muscular Dystrophy.
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Bilateral Brain Dynamics Supporting Cognition in Normal Aging and Dementia
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Biomarkers predicting response to eculizumab in MG (NonFed)
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Biomarkers predicting response to eculizumab in myasthenia gravis
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Biomedical Researcher Development Scholarship (BRDS) Research Career Development Award (K12)
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CSF EV Mito DNA workflow: Determination of feasibility of measurement of Mitochondrial DNA and Mitochondrial DNA integrity in human CSF-derived extracellular vesicles (EV)
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Characterization of total body muscle mass and muscle protein fractional synthesis rate in boys with Duchenne muscular dystrophy
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Clinical Protocol for a Phase II Open-label, Multicenter Long-term Extension Study to Assess the Long-term Safety and Efficacy of Vamorolone in Boys with Duchenne Muscular Dystrophy (DMD)
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Clinical Research in ALS & Related Disorders for Therapeutic Development (CREATE)
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Copy Number Alterations in Low Mutation Cancer
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Cross-validation of LRRK2 biomarkers
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DNA Blood Sampling Services - Base Year
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DNA Blood Sampling Services - Option Year 1
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Development of a Novel Model for Tourettes Syndrome
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Duke ALS Telemedicine Clinic
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EFFECTS OF ORAL LEVOSIMENDAN (ODM-109) ON RESPIRATORY FUNCTION IN
PATIENTS WITH ALS: OPEN-LABEL EXTENSION FOR PATIENTS COMPLETING
STUDY 3119002
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Efficacy of Nido Drug Compound BF3 in an animal model of SBMA
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Exploring the circuit mechanisms of motor and mood dysfunction in the CD157/BST1 KO mouse
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ExtracorPoreal FILtration of Subarachnoid Hemorrhage via SpinaL CAtheteR EXTension (PILLAR-XT)
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HDE Post-Approval Study (PAS) of NeuRx DPS for ALS
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Healey ALS Platform Trial Open Label Extension Zilucoplan
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Healy ALS Platform study - Regimen E ¿ Trehalose TO#10
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I AM ALS
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IPA - John F Ervin
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IPA-Richard Lawrence Whitley
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Identification of diagnostic peptides for the detection of sporadic amyotrophic lateral sclerosis (sALS)
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Integrated Genomics in Clinical ALS (GTAC)
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Interactions between the immune system, genetics and environmental mitochondrial toxicants in models of Parkinson's disease
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LRRK2 kinase activity and mitochondrial DNA damage in Parkinson's disease
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MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG TERM SAFETY OF PF-06252616 IN BOYS WITH DUCHENNE MUSCULAR DYSTROPHY
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Masticatory sensitization of trigeminal ganglion sensory neurons
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Mechanisms of mitochondrial genome integrity in familial and idiopathic Parkinson's disease
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Mechanisms of pathogenesis in LRRK2-related Parkinson's disease
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Mitochondrial DNA damage as a blood-based biomarker of early Parkinson's disease
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Mitochondrial DNA damage in PD and control in a pesticide-exposed cohort
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Mitochondrial DNA damage in brain and blood in Alzheimer's disease
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Mitochondrial DNA damage: screening tool and novel therapeutic target for Parkinson's disease
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North Carolina Regional Consortium for Brain Health in Aging
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PHASE 2, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, MULTIPLE DOSE STUDY OF CK-2127107 IN TWO ASCENDING DOSE COHORTS OF PATIENTS WITH SPINAL MUSCULAR ATROPHY (SMA)
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Potential Role of the Gut Microbiome in ALS Progression
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Potential Role of the Gut Microbiome in ALS Progression and Reversals
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Protocol CY 5022: A PHASE 2, MULTI-CENTER, DOUBLE-BLIND, RANDOMIZED, DOSE-RANGING, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY, AND TOLERABILITY OF CK-2127107 IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS)
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Sponsored research agreement: UCI
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Sponsored research agreement: UCI (DLAR)
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Sponsored research agreement: UCI (Macopson)
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Supplement: Mitochondrial DNA damage as a blood-based biomarker of early Parkinson's disease
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The Anti-Aging Role of Klotho in Skeletal Muscle Regeneration
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The Duke ALS Association Certified Center
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Using network-guided TMS to ameliorate memory deficits in early Alzheimer's disease
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Sub-Organizations