Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Residency and Fellowship in Psychiatry and Child and Adolescent Psychiatry, Psychiatry, Duke University School of Medicine 2007 - 2014
  • M.B.B.Ch., Stellenbosch University (South Africa) 2002
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  Previous Appointments & Affiliations

  • Assistant Research Professor of Global Health, Duke Global Health Institute, University Institutes and Centers 2014 - 2023
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry, Psychiatry & Behavioral Sciences 2021 - 2023
  • Assistant Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry, Psychiatry & Behavioral Sciences 2014 - 2020
• 

  Leadership & Clinical Positions at Duke

  • Cape Town Priority Partnership Lead, Duke Global Health Institute
• 

  Academic Positions Outside Duke

  • Honorary Senior Lecturer in the Division of Child & Adolescent Psychiatry , University of Cape Town. 2017 - 2023
• Recognition
• 

  In the News

  • SEP 15, 2021

    Duke Global Health Institute

    Raising the Bar on Global Disability Services

  • JAN 12, 2021

    Duke Global Health Institute

    Parenting for a Child With Autism During the COVID Pandemic
• Expertise
• 

  Global Scholarship

  • Research

    • South Africa (Country) 
    • United States of America (Country) 
• Research
• 

  Selected Grants

  • Machine Learning Methods to Develop and Deploy Real-Time Risk Surveillance for Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder from the Electronic Health Record awarded by National Institutes of Health 2022 - 2027
  • Caregiver Coaching to Improve Outcomes of Young Autistic Children in Africa awarded by National Institutes of Health 2022 - 2027
  • Extension for IMPACT Phase 2 Clinical Trial awarded by CryoCell International 2022 - 2024
  • Tailoring treatment targets for early autism intervention in Africa awarded by National Institutes of Health 2019 - 2023
  • Marcus Foundation Phase II MSC ASD awarded by The Marcus Foundation 2019 - 2022
  • Pilot Study to Improve Access to Early Intervention for Autism in Africa awarded by National Institutes of Health 2015 - 2021
  • A Study to Assess the Janssen Autism Knowledge Engine in Children and Adults with Autism Spectrum Disorder and in a Normally Developing Cohort awarded by Janssen Research & Development, LLC 2015 - 2016
  • Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor) awarded by Vanderbilt University Medical Center 2013 - 2014
• 

  External Relationships

  • Autism Speaks
  • University of Cape Town
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Coffman, Marika, J Matias Di Martino, Rachel Aiello, Kimberly L. H. Carpenter, Zhuoqing Chang, Scott Compton, Brian Eichner, et al. “Relationship between quantitative digital behavioral features and clinical profiles in young autistic children.” Autism Res, June 1, 2023. https://doi.org/10.1002/aur.2955.
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    • Rieder, Amber D., Marisa Viljoen, Noleen Seris, Nokuthula Shabalala, Minkateko Ndlovu, Elizabeth L. Turner, Ryan Simmons, Petrus J. de Vries, and Lauren Franz. “Improving access to early intervention for autism: findings from a proof-of-principle cascaded task-sharing naturalistic developmental behavioural intervention in South Africa.” Child Adolesc Psychiatry Ment Health 17, no. 1 (May 20, 2023): 64. https://doi.org/10.1186/s13034-023-00611-0.
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    • Yuan, Andrew, Maura Sabatos-DeVito, Alexandra L. Bey, Samantha Major, Kimberly Lh Carpenter, Lauren Franz, Jill Howard, et al. “Automated movement tracking of young autistic children during free play is correlated with clinical features associated with autism.” Autism, May 8, 2023, 13623613231169546. https://doi.org/10.1177/13623613231169546.
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    • Krishnappa Babu, Pradeep Raj, Vikram Aikat, J Matias Di Martino, Zhuoqing Chang, Sam Perochon, Steven Espinosa, Rachel Aiello, et al. “Blink rate and facial orientation reveal distinctive patterns of attentional engagement in autistic toddlers: a digital phenotyping approach.” Sci Rep 13, no. 1 (May 3, 2023): 7158. https://doi.org/10.1038/s41598-023-34293-7.
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    • Wall, Carla A., Maura Sabatos-DeVito, Lauren Franz, Jill Howard, Samantha Major, Alexandra Bey, and Geraldine Dawson. “Eye-tracking measures of social versus nonsocial attention are related to level of social engagement during naturalistic caregiver-child interactions in autistic children.” Autism Res 16, no. 5 (May 2023): 1052–62. https://doi.org/10.1002/aur.2920.
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    • Isaev, Dmitry Yu, Maura Sabatos-DeVito, J Matias Di Martino, Kimberly Carpenter, Rachel Aiello, Scott Compton, Naomi Davis, et al. “Computer Vision Analysis of Caregiver-Child Interactions in Children with Neurodevelopmental Disorders: A Preliminary Report.” J Autism Dev Disord, April 27, 2023. https://doi.org/10.1007/s10803-023-05973-0.
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    • Guler, Jessy, Kearsley A. Stewart, Petrus J. de Vries, Noleen Seris, Nokuthula Shabalala, and Lauren Franz. “Conducting caregiver focus groups on autism in the context of an international research collaboration: Logistical and methodological lessons learned in South Africa.” Autism 27, no. 3 (April 2023): 751–61. https://doi.org/10.1177/13623613221117012.
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    • Howard, Jill, Brianna Herold, Samantha Major, Caroline Leahy, Kevin Ramseur, Lauren Franz, Megan Deaver, et al. “Associations between executive function and attention abilities and language and social communication skills in young autistic children.” Autism, February 19, 2023, 13623613231154310. https://doi.org/10.1177/13623613231154310.
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    • Perochon, Sam, J. Matias Di Martino, Kimberly L. H. Carpenter, Scott Compton, Naomi Davis, Steven Espinosa, Lauren Franz, et al. “A tablet-based game for the assessment of visual motor skills in autistic children.” Npj Digit Med 6, no. 1 (February 3, 2023): 17. https://doi.org/10.1038/s41746-023-00762-6.
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    • Krishnappa Babu, Pradeep Raj, J Matias Di Martino, Zhuoqing Chang, Sam Perochon, Rachel Aiello, Kimberly L. H. Carpenter, Scott Compton, et al. “Complexity analysis of head movements in autistic toddlers.” J Child Psychol Psychiatry 64, no. 1 (January 2023): 156–66. https://doi.org/10.1111/jcpp.13681.
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    • Dawson, Geraldine, Lauren Franz, and S. Brandsen. “Neurodiversity and Early Autism-Reply.” Jama Pediatr 176, no. 12 (December 1, 2022): 1273–74. https://doi.org/10.1001/jamapediatrics.2022.4147.
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    • Carpenter, Kimberly L. H., Naomi O. Davis, Marina Spanos, Maura Sabatos-DeVito, Rachel Aiello, Grace T. Baranek, Scott N. Compton, et al. “Adaptive Behavior in Young Autistic Children: Associations with Irritability and ADHD Symptoms.” J Autism Dev Disord, October 12, 2022. https://doi.org/10.1007/s10803-022-05753-2.
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    • Dawson, Geraldine, Lauren Franz, and S. Brandsen. “At a Crossroads-Reconsidering the Goals of Autism Early Behavioral Intervention From a Neurodiversity Perspective.” Jama Pediatr 176, no. 9 (September 1, 2022): 839–40. https://doi.org/10.1001/jamapediatrics.2022.2299.
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    • Franz, Lauren, Cara D. Goodwin, Amber Rieder, Maya Matheis, and Diane L. Damiano. “Early intervention for very young children with or at high likelihood for autism spectrum disorder: An overview of reviews.” Dev Med Child Neurol 64, no. 9 (September 2022): 1063–76. https://doi.org/10.1111/dmcn.15258.
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    • Major, Samantha, Dmitry Isaev, Jordan Grapel, Todd Calnan, Elena Tenenbaum, Kimberly Carpenter, Lauren Franz, et al. “Shorter average look durations to dynamic social stimuli are associated with higher levels of autism symptoms in young autistic children.” Autism 26, no. 6 (August 2022): 1451–59. https://doi.org/10.1177/13623613211056427.
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    • Dawson-Squibb, John-Joe, Eugene Lee Davids, Rhea Chase, Eve Puffer, Justin D. M. Rasmussen, Lauren Franz, and Petrus J. de Vries. “Bringing Parent-Child Interaction Therapy to South Africa: Barriers and Facilitators and Overall Feasibility-First Steps to Implementation.” Int J Environ Res Public Health 19, no. 8 (April 7, 2022). https://doi.org/10.3390/ijerph19084450.
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    • Franz, Lauren, Jill Howard, Marisa Viljoen, Linmarie Sikich, Tara Chandrasekhar, Scott H. Kollins, Lawrence Lee, et al. “Pragmatic adaptations of telehealth-delivered caregiver coaching for children with autism in the context of COVID-19: Perspectives from the United States and South Africa.” Autism 26, no. 1 (January 2022): 270–75. https://doi.org/10.1177/13623613211022585.
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    • Perochon, Sam, Matias Di Martino, Rachel Aiello, Jeffrey Baker, Kimberly Carpenter, Zhuoqing Chang, Scott Compton, et al. “A scalable computational approach to assessing response to name in toddlers with autism.” J Child Psychol Psychiatry 62, no. 9 (September 2021): 1120–31. https://doi.org/10.1111/jcpp.13381.
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    • Chang, Zhuoqing, J Matias Di Martino, Rachel Aiello, Jeffrey Baker, Kimberly Carpenter, Scott Compton, Naomi Davis, et al. “Computational Methods to Measure Patterns of Gaze in Toddlers With Autism Spectrum Disorder.” Jama Pediatr 175, no. 8 (August 1, 2021): 827–36. https://doi.org/10.1001/jamapediatrics.2021.0530.
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    • Kim, Eunsoo Timothy, Lauren Franz, Danai Kasambira Fannin, Jill Howard, and Gary Maslow. “Educational classifications of autism spectrum disorder and intellectual disability among school-aged children in North Carolina: Associations with race, rurality, and resource availability.” Autism Res 14, no. 5 (May 2021): 1046–60. https://doi.org/10.1002/aur.2492.
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    • Pham, Tony V., Bonnie N. Kaiser, Rishav Koirala, Sujen Man Maharjan, Nawaraj Upadhaya, Lauren Franz, and Brandon A. Kohrt. “Traditional Healers and Mental Health in Nepal: A Scoping Review.” Cult Med Psychiatry 45, no. 1 (March 2021): 97–140. https://doi.org/10.1007/s11013-020-09676-4.
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    • Chakraborty, Payal, Kimberly L. H. Carpenter, Samantha Major, Megan Deaver, Saritha Vermeer, Brianna Herold, Lauren Franz, Jill Howard, and Geraldine Dawson. “Gastrointestinal problems are associated with increased repetitive behaviors but not social communication difficulties in young children with autism spectrum disorders.” Autism 25, no. 2 (February 2021): 405–15. https://doi.org/10.1177/1362361320959503.
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    • Ivanov, I., I. Pacheva, E. Timova, R. Iordanova, F. Galabova, K. Gaberova, A. Petkova, et al. “The route to autism spectrum diagnosis in pediatric practice in Bulgaria.” Diagnostics 11, no. 1 (January 1, 2021). https://doi.org/10.3390/diagnostics11010106.
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    • Sun, Jessica M., Geraldine Dawson, Lauren Franz, Jill Howard, Colleen McLaughlin, Bethany Kistler, Barbara Waters-Pick, Norin Meadows, Jesse Troy, and Joanne Kurtzberg. “Infusion of human umbilical cord tissue mesenchymal stromal cells in children with autism spectrum disorder.” Stem Cells Transl Med 9, no. 10 (October 2020): 1137–46. https://doi.org/10.1002/sctm.19-0434.
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    • Dawson, Geraldine, Jessica M. Sun, Jennifer Baker, Kimberly Carpenter, Scott Compton, Megan Deaver, Lauren Franz, et al. “A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder.” J Pediatr 222 (July 2020): 164-173.e5. https://doi.org/10.1016/j.jpeds.2020.03.011.
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    • Franz, Lauren, and Geraldine Dawson. “Implementing early intervention for autism spectrum disorder: a global perspective.” Pediatr Med 2 (August 2019). https://doi.org/10.21037/pm.2019.07.09.
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    • Makombe, C. B. T., N. Shabalala, M. Viljoen, N. Seris, P. J. de Vries, and L. Franz. “Sustainable implementation of early intervention for autism spectrum disorder through caregiver coaching: South African perspectives on barriers and facilitators.” Pediatric Medicine 2 (August 1, 2019). https://doi.org/10.21037/pm.2019.07.08.
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    • Ramseur, Kevin, Petrus J. de Vries, Jessy Guler, Nokuthula Shabalala, Noleen Seris, and Lauren Franz. “Caregiver descriptions of joint activity routines with young children with autism spectrum disorder in South Africa.” Pediatr Med 2 (March 2019). https://doi.org/10.21037/pm.2019.03.04.
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    • Carpenter, Kimberly L. H., Samantha Major, Catherine Tallman, Lyon W. Chen, Lauren Franz, Jessica Sun, Joanne Kurtzberg, Allen Song, and Geraldine Dawson. “White Matter Tract Changes Associated with Clinical Improvement in an Open-Label Trial Assessing Autologous Umbilical Cord Blood for Treatment of Young Children with Autism.” Stem Cells Transl Med 8, no. 2 (February 2019): 138–47. https://doi.org/10.1002/sctm.18-0251.
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    • Franz, Lauren, Konyin Adewumi, Nola Chambers, Marisa Viljoen, Joy Noel Baumgartner, and Petrus J. de Vries. “Providing early detection and early intervention for autism spectrum disorder in South Africa: stakeholder perspectives from the Western Cape province.” J Child Adolesc Ment Health 30, no. 3 (November 2018): 149–65. https://doi.org/10.2989/17280583.2018.1525386.
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    • Guler, Jessy, Petrus J. de Vries, Noleen Seris, Nokuthula Shabalala, and Lauren Franz. “The importance of context in early autism intervention: A qualitative South African study.” Autism 22, no. 8 (November 2018): 1005–17. https://doi.org/10.1177/1362361317716604.
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    • Murias, Michael, Samantha Major, Katherine Davlantis, Lauren Franz, Adrianne Harris, Benjamin Rardin, Maura Sabatos-DeVito, and Geraldine Dawson. “Validation of eye-tracking measures of social attention as a potential biomarker for autism clinical trials.” Autism Res 11, no. 1 (January 2018): 166–74. https://doi.org/10.1002/aur.1894.
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    • Dawson, Geraldine, Jessica M. Sun, Katherine S. Davlantis, Michael Murias, Lauren Franz, Jesse Troy, Ryan Simmons, Maura Sabatos-DeVito, Rebecca Durham, and Joanne Kurtzberg. “Autologous Cord Blood Infusions Are Safe and Feasible in Young Children with Autism Spectrum Disorder: Results of a Single-Center Phase I Open-Label Trial.” Stem Cells Transl Med 6, no. 5 (May 2017): 1332–39. https://doi.org/10.1002/sctm.16-0474.
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    • Franz, Lauren, Nola Chambers, Megan von Isenburg, and Petrus J. de Vries. “Autism spectrum disorder in sub-saharan africa: A comprehensive scoping review.” Autism Res 10, no. 5 (May 2017): 723–49. https://doi.org/10.1002/aur.1766.
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    • Maselko, Joanna, Siham Sikander, Omer Bangash, Sonia Bhalotra, Lauren Franz, Nima Ganga, Divya Guru Rajan, Karen O’Donnell, and Atif Rahman. “Child mental health and maternal depression history in Pakistan.” Soc Psychiatry Psychiatr Epidemiol 51, no. 1 (January 2016): 49–62. https://doi.org/10.1007/s00127-015-1143-x.
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    • Zivony, Alon, and Dominique Lamy. “Dissociation between Attentional Capture and Attentional Engagement: an Attentional Blink study.” Journal of Vision 15, no. 12 (September 1, 2015): 1232–1232. https://doi.org/10.1167/15.12.1232.
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    • Zucker, Nancy, William Copeland, Lauren Franz, Kimberly Carpenter, Lori Keeling, Adrian Angold, and Helen Egger. “Psychological and Psychosocial Impairment in Preschoolers With Selective Eating.” Pediatrics 136, no. 3 (September 2015): e582–90. https://doi.org/10.1542/peds.2014-2386.
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    • Maselko, Joanna, Siham Sikander, Sonia Bhalotra, Omer Bangash, Nima Ganga, Satadru Mukherjee, Helen Egger, et al. “Effect of an early perinatal depression intervention on long-term child development outcomes: follow-up of the Thinking Healthy Programme randomised controlled trial.” Lancet Psychiatry 2, no. 7 (July 2015): 609–17. https://doi.org/10.1016/S2215-0366(15)00109-1.
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    • Towe-Goodman, Nissa R., Lauren Franz, William Copeland, Adrian Angold, and Helen Egger. “Perceived family impact of preschool anxiety disorders.” J Am Acad Child Adolesc Psychiatry 53, no. 4 (April 2014): 437–46. https://doi.org/10.1016/j.jaac.2013.12.017.
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    • Franz, Lauren, Adrian Angold, William Copeland, E Jane Costello, Nissa Towe-Goodman, and Helen Egger. “Preschool anxiety disorders in pediatric primary care: prevalence and comorbidity.” J Am Acad Child Adolesc Psychiatry 52, no. 12 (December 2013): 1294-1303.e1. https://doi.org/10.1016/j.jaac.2013.09.008.
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    • Deepmala, Deepmala, Lauren Franz, Carolina Aponte, Mayank Agrawal, and Wei Jiang. “Identification of provider characteristics influencing prescription of analgesics: a systematic literature review.” Pain Pract 13, no. 6 (July 2013): 504–13. https://doi.org/10.1111/papr.12007.
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    • Goulding, Sandra M., Lauren Franz, Erin Bergner, and Michael T. Compton. “Social functioning in urban, predominantly African American, socially disadvantaged patients with first-episode nonaffective psychosis.” Schizophr Res 119, no. 1–3 (June 2010): 95–100. https://doi.org/10.1016/j.schres.2009.12.018.
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    • Franz, Lauren, Tandrea Carter, Amy S. Leiner, Erin Bergner, Nancy J. Thompson, and Michael T. Compton. “Stigma and treatment delay in first-episode psychosis: a grounded theory study.” Early Interv Psychiatry 4, no. 1 (February 2010): 47–56. https://doi.org/10.1111/j.1751-7893.2009.00155.x.
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    • Lee, Jonathan, Lauren Franz, and Harold W. Goforth. “Serotonin syndrome in a chronic-pain patient receiving concurrent methadone, ciprofloxacin, and venlafaxine.” Psychosomatics 50, no. 6 (2009): 638–39. https://doi.org/10.1176/appi.psy.50.6.638.
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    • Compton, M. T., A. S. Leiner, E. Bergner, V. H. Chien, L. Franz, S. M. Goulding, and H. Trotman. “Prevalence, factorial structure, and clinical correlates of first rank symptoms in urban, African-American patients with first-episode nonaffective psychosis.” Clinical Schizophrenia and Related Psychoses 2, no. 1 (April 1, 2008): 59–69. https://doi.org/10.3371/CSRP.2.1.4.
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    • Bergner, Erin, Amy S. Leiner, Tandrea Carter, Lauren Franz, Nancy J. Thompson, and Michael T. Compton. “The period of untreated psychosis before treatment initiation: a qualitative study of family members' perspectives.” Compr Psychiatry 49, no. 6 (2008): 530–36. https://doi.org/10.1016/j.comppsych.2008.02.010.
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• Scholarly, Clinical, & Service Activities
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  Outreach & Engaged Scholarship

  • Pilot Study to Improve Access to Early Intervention for Autism in Africa. Pilot Study to Improve Access to Early Intervention for Autism in Africa. University of Cape Town . August 2015  2015

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