Overview
Dr. Klotman became Dean of the Duke School of Medicine in June 2017.
An accomplished clinician and scientist, Klotman’s research interests are focused on the molecular pathogenesis of Human Immunodeficiency Virus 1 (HIV-1) infection.
Among many important contributions to this field, Klotman and her team demonstrated that HIV resides in and evolves separately in kidney cells, a critical step in HIV-associated kidney disease. Her research group also has determined the role of soluble host factors involved in an innate immune response to HIV in an effort to improve prevention strategies, topical microbicides that could be used to block sexual transmission of HIV.
Most recently, her group has been defining the role of integrase-defective lentiviral vectors for the delivery of an HIV vaccine. (Read the announcement.)
An accomplished clinician and scientist, Klotman’s research interests are focused on the molecular pathogenesis of Human Immunodeficiency Virus 1 (HIV-1) infection.
Among many important contributions to this field, Klotman and her team demonstrated that HIV resides in and evolves separately in kidney cells, a critical step in HIV-associated kidney disease. Her research group also has determined the role of soluble host factors involved in an innate immune response to HIV in an effort to improve prevention strategies, topical microbicides that could be used to block sexual transmission of HIV.
Most recently, her group has been defining the role of integrase-defective lentiviral vectors for the delivery of an HIV vaccine. (Read the announcement.)
Current Appointments & Affiliations
R.J. Reynolds Distinguished Professor of Medicine
·
2011 - Present
Medicine, Infectious Diseases,
Medicine
Professor of Medicine
·
2010 - Present
Medicine, Infectious Diseases,
Medicine
Dean, School of Medicine
·
2017 - Present
School of Medicine
Executive Vice President of Health Affairs
·
2023 - Present
School of Medicine
Professor in Molecular Genetics and Microbiology
·
2011 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Professor of Pathology
·
2013 - Present
Pathology,
Clinical Science Departments
Member of the Duke Human Vaccine Institute
·
2010 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Education, Training & Certifications
Duke University ·
1980
M.D.