Overview
Pamela S Douglas MD is the Ursula Geller Professor of Research in Cardiovascular Diseases in the Department of Medicine at Duke University and Director of the Multimodality Imaging Program at Duke Clinical Research Institute. During her 30+ years of experience she has led several landmark multicenter government studies and pivotal industry clinical trials along with outcomes research studies. She is renowned for her scientific and policy work in improving the quality and appropriateness of imaging in clinical care, clinical trials and registries and through development and dissemination of national standards for imaging utilization, informatics and analysis. She has been among the pioneers in a number of areas including heart disease in women, sports cardiology, and cardio-oncology. Dr. Douglas’ wealth of experience includes authorship of over 400 peer reviewed manuscripts and 30 practice guidelines, and service as the President of the American College of Cardiology, President of the American Society of Echocardiography, and Chief of Cardiology at both the University of Wisconsin and Duke University. She has also previously served on the faculties of the University of Pennsylvania and Harvard University. She currently serves on the External Advisory Council of the National Heart, Lung and Blood Institute and the Scientific Advisory Board of the Patient Advocate Foundation.
Current Duke Appointments & Affiliations
Recent Scholarly Works
Opportunistic CT-Derived Periaortic Fat Attenuation as a Novel Marker of Mortality in Patients Undergoing TAVR.
Journal article JACC Cardiovasc Imaging · August 2026 Full text Link to item CiteDesign and Rationale of the pERSonalized cardIovascuLar dIsease prEvention, treatmeNt, and CarE (RESILIENCE) study.
Journal article Contemp Clin Trials · August 2026 BACKGROUND: Obesity is a growing epidemic associated with cardiovascular disease (CVD). The RESILIENCE study aimed to understand the factors underlying heterogeneity in CVD development among individuals with obesity as well as the variability in response t ... Full text Link to item CiteProteomic Signatures of High-Risk Coronary Plaque Features and Incident Events.
Journal article JACC Basic Transl Sci · July 22, 2026 Patients with and without obstructive coronary artery disease (oCAD) experience heterogeneous cardiovascular risk, and coronary computed tomography angiography (CCTA) high-risk plaque features are not universally available. This study evaluated whether cir ... Full text Link to item CiteRecent Grants
Molecular predictors of cardiovascular events and resilience in chronic coronary artery disease
ResearchCo Investigator · Awarded by NYU Langone Medical Center · 2023 - 20281/2 PREEMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2027Pericoronary adipose tissue density a novel CT-derived marker of local inflammation and coronary artery disease in patients living with HIV
ResearchPrincipal Investigator · Awarded by Massachusetts General Hospital · 2023 - 2027View All Grants