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The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches.

Publication ,  Journal Article
McVay, MA; Jeffreys, AS; King, HA; Olsen, MK; Voils, CI; Yancy, WS
Published in: J Hum Nutr Diet
February 2015

BACKGROUND: Identifying pretreatment dietary habits that are associated with weight-loss intervention outcomes could help guide individuals' selection of weight-loss approach among competing options. A pretreatment factor that may influence weight-loss outcomes is macronutrient intake. METHODS: Overweight and obese Durham Veterans Affairs outpatients were randomised to a weight-loss intervention with a low-carbohydrate diet (n = 71) or orlistat medication therapy plus a low-fat diet (n = 73). Percentage fat, carbohydrate and protein intake prior to treatment were measured using 4-day food records. Linear mixed-effects models were used to determine whether pretreatment percentage macronutrient intake influenced weight trajectories and weight loss in each weight-loss condition. RESULTS: Participant's mean age was 53 years, baseline body mass index was 39.3 kg m(-2) and 72% were male. A higher pretreatment percentage carbohydrate intake was associated with less rapid initial weight loss (P = 0.02) and less rapid weight regain (P = 0.03) in the low-carbohydrate diet condition but was not associated with weight trajectories in the orlistat plus low-fat diet condition. In both conditions, a higher pretreatment percentage fat intake was associated with more rapid weight regain (P < 0.01). Pretreatment percentage protein intake was not associated with weight trajectories. None of the pretreatment macronutrients were associated with weight loss on study completion in either condition. CONCLUSIONS: Selection of a weight-loss approach on the basis of pretreatment macronutrient intake is unlikely to improve weight outcomes at the end of a 1-year treatment. However, pretreatment macronutrient intake may have implications for tailoring of interventions to slow weight regain after weight loss.

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Published In

J Hum Nutr Diet

DOI

EISSN

1365-277X

Publication Date

February 2015

Volume

28 Suppl 2

Start / End Page

16 / 23

Location

England

Related Subject Headings

  • Weight Loss
  • Weight Gain
  • Orlistat
  • Obesity
  • Nutrition & Dietetics
  • Middle Aged
  • Male
  • Lactones
  • Humans
  • Female
 

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McVay, M. A., Jeffreys, A. S., King, H. A., Olsen, M. K., Voils, C. I., & Yancy, W. S. (2015). The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches. J Hum Nutr Diet, 28 Suppl 2, 16–23. https://doi.org/10.1111/jhn.12188
McVay, M. A., A. S. Jeffreys, H. A. King, M. K. Olsen, C. I. Voils, and W. S. Yancy. “The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches.J Hum Nutr Diet 28 Suppl 2 (February 2015): 16–23. https://doi.org/10.1111/jhn.12188.
McVay MA, Jeffreys AS, King HA, Olsen MK, Voils CI, Yancy WS. The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches. J Hum Nutr Diet. 2015 Feb;28 Suppl 2:16–23.
McVay, M. A., et al. “The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches.J Hum Nutr Diet, vol. 28 Suppl 2, Feb. 2015, pp. 16–23. Pubmed, doi:10.1111/jhn.12188.
McVay MA, Jeffreys AS, King HA, Olsen MK, Voils CI, Yancy WS. The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches. J Hum Nutr Diet. 2015 Feb;28 Suppl 2:16–23.
Journal cover image

Published In

J Hum Nutr Diet

DOI

EISSN

1365-277X

Publication Date

February 2015

Volume

28 Suppl 2

Start / End Page

16 / 23

Location

England

Related Subject Headings

  • Weight Loss
  • Weight Gain
  • Orlistat
  • Obesity
  • Nutrition & Dietetics
  • Middle Aged
  • Male
  • Lactones
  • Humans
  • Female