Percolation, morphogenesis, and burgers dynamics in blood vessels formation.

Journal Article (Journal Article)

Experiments of in vitro formation of blood vessels show that cells randomly spread on a gel matrix autonomously organize to form a connected vascular network. We propose a simple model which reproduces many features of the biological system. We show that both the model and the real system exhibit a fractal behavior at small scales, due to the process of migration and dynamical aggregation, followed at large scale by a random percolation behavior due to the coalescence of aggregates. The results are in good agreement with the analysis performed on the experimental data.

Full Text

Duke Authors

Cited Authors

  • Gamba, A; Ambrosi, D; Coniglio, A; de Candia, A; Di Talia, S; Giraudo, E; Serini, G; Preziosi, L; Bussolino, F

Published Date

  • March 21, 2003

Published In

Volume / Issue

  • 90 / 11

Start / End Page

  • 118101 -

PubMed ID

  • 12688968

International Standard Serial Number (ISSN)

  • 0031-9007

Digital Object Identifier (DOI)

  • 10.1103/PhysRevLett.90.118101

Language

  • eng

Conference Location

  • United States