Isolated limb infusion as a model to test new agents to treat metastatic melanoma.
Journal Article (Review)
The limb model of in-transit disease can expand our understanding of treating melanoma because of the ease of obtaining tissue biopsies for correlative studies and the availability of preclinical animal models that allow validation of novel therapeutic strategies. This review will focus on regional therapy for in-transit melanoma as a platform to investigate novel therapeutic approaches to improve regional disease control, and help us develop insights to more rationally design systemic therapy trials.
Full Text
Duke Authors
Cited Authors
- Lidsky, ME; Speicher, PJ; Jiang, B; Tsutsui, M; Tyler, DS
Published Date
- March 2014
Published In
Volume / Issue
- 109 / 4
Start / End Page
- 357 - 365
PubMed ID
- 24522940
Pubmed Central ID
- 24522940
Electronic International Standard Serial Number (EISSN)
- 1096-9098
Digital Object Identifier (DOI)
- 10.1002/jso.23502
Language
- eng
Conference Location
- United States