Bacteria Localization and Chorion Thinning among Preterm Premature Rupture of Membranes


Journal Article (Academic article)

Bacterial colonization of the fetal membranes and its role in pathogenesis of membrane rupture is poorly understood. Prior retrospective work revealed chorion layer thinning in preterm premature rupture of membranes (PPROM) subjects. Our objective was to prospectively examine fetal membrane chorion thinning and to correlate to bacterial presence in PPROM, preterm, and term subjects.

Full Text

Duke Authors

Cited Authors

  • Murtha, AP; Fortner, KB; Grotegut, CA; Ransom, CE; Bentley, RC; Feng, L; Lan, L; Heine, RP; Seed, PC

Published Date

  • January 8, 2014

Published In

  • Plos One

Published By

PubMed ID

  • 24421883

Pubmed Central ID

  • 24421883

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0083338


  • English