Rashes are among the most common manifestations of systemic lupus erythematosus (SLE), affecting up to 85% of individuals with SLE. Cutaneous lupus without systemic features is even more common than SLE. In many patients, cutaneous involvement can be widespread and debilitating, requiring systemic treatment. Here, two challenging cases of cutaneous lupus are described. © Springer Science+Business Media, LLC 2010.
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