The Influence of Comorbid Depression and Conduct Disorder on MET/CBT Treatment Outcome for Adolescent Substance Use Disorders.


Journal Article

Although depression and conduct disorder frequently co-occur with substance use disorders (SUDs), few studies have investigated the individual and interactive effects of these conditions on SUD treatment outcome. Data were collected from 90 adolescents aged 13-21 (M = 17.1, SD = 2.07) who received a brief evidence-based intervention for SUD. Hierarchical regressions assessed the relationship among demographic variables, depression, conduct disorder, and two substance use outcomes (frequency and problems) at two intervals (three months, six months). Results revealed that higher baseline substance use and lower socioeconomic status significantly predicted higher substance problems and frequency at three-months. At six months, higher three month substance problems and lower depressive symptoms predicted substance problems. In addition, an interaction indicated that the effect of conduct disorder on substance problems was greatest at lower levels of depression. Results are discussed in the context of previous research indicating mixed effects of depression on SUD treatment outcome.

Full Text

Duke Authors

Cited Authors

  • Hersh, J; Curry, JF; Becker, SJ

Published Date

  • December 1, 2013

Published In

Volume / Issue

  • 6 / 4

Start / End Page

  • 325 - 341

PubMed ID

  • 25197427

Pubmed Central ID

  • 25197427

International Standard Serial Number (ISSN)

  • 1937-1209

Digital Object Identifier (DOI)

  • 10.1521/ijct.2013.6.4.325


  • eng

Conference Location

  • Switzerland