Characterization of a photoswitching chelator with light-modulated geometric, electronic, and metal-binding properties.

Journal Article

Photoswitching molecules are utilized for a variety of applications where the rapid manipulation of the molecules' chemical properties and spatial orientations allows for new spatiotemporal control over molecular-scale interactions and processes. Here, we present a hydrazone-containing transition metal chelator, HAPI ((E)-N'-[1-(2-hydroxyphenyl)ethyliden]isonicotinoylhydrazide), that displays dual-wavelength photoswitching behavior. Several of its metal complexes, however, are inert to photoreaction and thereby add another layer of control over the photoswitch system. The light-induced twist in HAPI structure is accompanied by a dramatic change in electronic properties as well as chelator strength. This work introduces HAPI as the prototype for a class of molecules with properties that may be optimized for a variety of experimental applications that take advantage of phototriggered molecular changes.

Full Text

Duke Authors

Cited Authors

  • Franks, AT; Peng, D; Yang, W; Franz, KJ

Published Date

  • February 2014

Published In

Volume / Issue

  • 53 / 3

Start / End Page

  • 1397 - 1405

PubMed ID

  • 24428136

Electronic International Standard Serial Number (EISSN)

  • 1520-510X

International Standard Serial Number (ISSN)

  • 0020-1669

Digital Object Identifier (DOI)

  • 10.1021/ic402221x

Language

  • eng