Insulin continues to be the preferred method for the management of hyperglycemia in the inpatient setting. It can be titrated easily, does not have a ceiling dose, and can be administered intravenously and subcutaneously. Details of IV insulin, including the transition from IV to subcutaneous, are discussed in Chapter 3: IV Insulin. In this chapter, we focus on subcutaneous insulin regimens. © 2011 Springer Science+Business Media, LLC.