Optic nerve malformations


Book Section

Optic nerve hypoplasia is a morphological description of a small-appearing optic nerve due to a decreased number of axons traveling from the retinal ganglion cells through the optic nerve head to the optic chiasm and lateral geniculate nucleus (Fig. 5.1). This results from either a primary lack of retinal ganglion cell and axon development or a retrograde loss of axons from disturbances in the posterior visual pathways before birth. Optic nerve hypoplasia is often associated with a number of midline intracranial malformations (septo-optic dysplasia or de Morsier's syndrome) as well as structural brain abnormalities (schizencephaly, proencephaly). © 2011 Springer-Verlag Berlin Heidelberg.

Full Text

Duke Authors

Cited Authors

  • Buckley, EG; Gearinger, M; Jing, J; Mahmoud, T

Published Date

  • December 1, 2011

Book Title

  • Pediatric Retina

Start / End Page

  • 117 - 145

International Standard Book Number 13 (ISBN-13)

  • 9783642120404

Digital Object Identifier (DOI)

  • 10.1007/978-3-642-12041-1_5

Citation Source

  • Scopus