Central centrifugal cicatricial alopecia: what has been achieved, current clues for future research.

Journal Article (Journal Article;Review)

Central centrifugal cicatricial alopecia is an inflammatory type of central scalp hair loss seen primarily in women of African descent. The prevalence is unknown, but may vary from 2.7% to 5.7% and increases with age. This review outlines the history and current beliefs and identifies clues for future research for this enigmatic condition. Despite that the cause of central centrifugal cicatricial alopecia is unknown, research is ongoing. The role of cytokeratins, androgens, genetics, and various possible sources of chronic inflammation in disease pathogenesis remain to be elucidated.

Full Text

Duke Authors

Cited Authors

  • Ogunleye, TA; McMichael, A; Olsen, EA

Published Date

  • April 2014

Published In

Volume / Issue

  • 32 / 2

Start / End Page

  • 173 - 181

PubMed ID

  • 24680004

Electronic International Standard Serial Number (EISSN)

  • 1558-0520

Digital Object Identifier (DOI)

  • 10.1016/j.det.2013.12.005


  • eng

Conference Location

  • United States