Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions.

Journal Article (Journal Article)

We have previously shown that intracardiac acoustic radiation force impulse (ARFI) imaging visualizes tissue stiffness changes caused by radiofrequency ablation (RFA). The objectives of this in vivo study were to (1) quantify measured ARFI-induced displacements in RFA lesion and unablated myocardium and (2) calculate the lesion contrast (C) and contrast-to-noise ratio (CNR) in two-dimensional ARFI and conventional intracardiac echo images. In eight canine subjects, an ARFI imaging-electroanatomical mapping system was used to map right atrial ablation lesion sites and guide the acquisition of ARFI images at these sites before and after ablation. Readers of the ARFI images identified lesion sites with high sensitivity (90.2%) and specificity (94.3%) and the average measured ARFI-induced displacements were higher at unablated sites (11.23 ± 1.71 µm) than at ablated sites (6.06 ± 0.94 µm). The average lesion C (0.29 ± 0.33) and CNR (1.83 ± 1.75) were significantly higher for ARFI images than for spatially registered conventional B-mode images (C = -0.03 ± 0.28, CNR = 0.74 ± 0.68).

Full Text

Duke Authors

Cited Authors

  • Eyerly, SA; Bahnson, TD; Koontz, JI; Bradway, DP; Dumont, DM; Trahey, GE; Wolf, PD

Published Date

  • April 2014

Published In

Volume / Issue

  • 36 / 2

Start / End Page

  • 133 - 148

PubMed ID

  • 24554293

Pubmed Central ID

  • PMC4049337

Electronic International Standard Serial Number (EISSN)

  • 1096-0910

Digital Object Identifier (DOI)

  • 10.1177/0161734613519602


  • eng

Conference Location

  • England