Symptomatic Rathke's cleft cyst with a co-existing pituitary tumor; Brief review of the literature.

Journal Article

Pituitary adenomas and Rathke's cleft cysts (RCCs) share a common embryological origin. Occasionally, these two lesions can present within the same patient. We present a case of a 39-year-old male who was found to have a large sellar lesion after complaints of persistent headaches and horizontal nystagmus. Surgical resection revealed components of a RCC co-existing with a pituitary adenoma. A brief review of the literature was performed revealing 38 cases of co-existing Rathke's cleft cysts and pituitary adenomas. Among the cases, the most common symptoms included headache and visual changes. Rathke's cleft cysts and pituitary adenomas are rarely found to co-exist, despite having common embryological origins. We review the existing literature, discuss the common embryology to these two lesions and describe a unique case from our institution of a co-existing Rathke's cleft cyst and pituitary adenoma.

Full Text

Duke Authors

Cited Authors

  • Babu, R; Back, AG; Komisarow, JM; Owens, TR; Cummings, TJ; Britz, GW

Published Date

  • October 2013

Published In

Volume / Issue

  • 8 / 4

Start / End Page

  • 183 - 187

PubMed ID

  • 24551002

Pubmed Central ID

  • PMC3912769

International Standard Serial Number (ISSN)

  • 1793-5482

Digital Object Identifier (DOI)

  • 10.4103/1793-5482.125662


  • eng

Conference Location

  • India