ADHD, altered dopamine neurotransmission, and disrupted reinforcement processes: implications for smoking and nicotine dependence.

Journal Article (Journal Article;Review)

Attention deficit hyperactivity disorder (ADHD) is a common and impairing disorder affecting millions of children, adolescents, and adults. Individuals with ADHD smoke cigarettes at rates significantly higher than their non-diagnosed peers and the disorder also confers risk for a number of related adverse smoking outcomes including earlier age of initiation, faster progression to regular use, heavier smoking/greater dependence, and more difficulty quitting. Progress in our understanding of dopamine neurotransmission and basic behavioral reinforcement processes in ADHD may help increase our understanding of the ADHD-smoking comorbidity. This review will examine how these areas have been studied and how further work may aid in the development of better prevention and treatment for smoking in those with ADHD.

Full Text

Duke Authors

Cited Authors

  • Kollins, SH; Adcock, RA

Published Date

  • July 3, 2014

Published In

Volume / Issue

  • 52 /

Start / End Page

  • 70 - 78

PubMed ID

  • 24560930

Pubmed Central ID

  • PMC4004668

Electronic International Standard Serial Number (EISSN)

  • 1878-4216

Digital Object Identifier (DOI)

  • 10.1016/j.pnpbp.2014.02.002


  • eng

Conference Location

  • England