Viscosupplementation for knee osteoarthritis.

Journal Article (Journal Article)


To provide an overview of the diagnosis and pathophysiology of osteoarthritis (OA), and to describe appropriate treatments for knee OA, with a focus on the efficacy and safety of viscosupplementation. Because nurse practitioners (NPs) can inject viscosupplements, a section on injection technique is included.

Data sources

Manuscripts were identified using PubMed and EMBASE with a review of the reference lists from retrieved articles.


Viscosupplements are safe and effective at improving function and alleviating knee pain from OA for up to 26 weeks.

Implications for practice

As the number of patients with OA is increasing, NPs need to be prepared to prescribe various treatment options to alleviate osteoarthritic knee pain, including viscosupplementation.

Full Text

Duke Authors

Cited Authors

  • Zychowicz, ME

Published Date

  • March 2014

Published In

Volume / Issue

  • 26 / 3

Start / End Page

  • 163 - 175

PubMed ID

  • 24574068

Electronic International Standard Serial Number (EISSN)

  • 2327-6924

International Standard Serial Number (ISSN)

  • 2327-6886

Digital Object Identifier (DOI)

  • 10.1002/2327-6924.12103


  • eng